Gene name	Blattner ID	Description	EcoCyc link	SwissProt comment
ompR	b3405	response regulator (sensor, EnvZ) affecting transcription of ompC and ompF: outer membrane protein synthesis	EG10672	FUNCTION: THE N-TERMINUS OF THIS PROTEIN IS REQUIRED FOR THE TRANSCRIPTIONAL EXPRESSION OF BOTH MAJOR OUTER MEMBRANE PROTEIN GENES OMPF AND OMPC; ITS CARBOXYL-TERMINAL MOIETY MEDIATES THE MULTIMERIZATION OF THE OMPR PROTEIN. AS A MULTIMER, IT TURNS ON THE EXPRESSION OF THE OMPC GENE; AS A MONOMER, IT TURNS ON THE EXPRESSION OF THE OMPF GENE. SUBUNIT: MONOMER AND MULTIMER. SUBCELLULAR LOCATION: CYTOPLASMIC. SIMILARITY: THE N-TERMINAL REGION IS SIMILAR TO THAT OF OTHER REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEMS. CAUTION: REF.1 SEQUENCE DIFFERS FROM THAT SHOWN IN THE C-TERMINUS AND IS LONGER (284 AA) DUE TO A FRAMESHIFT.
envZ	b3404	protein histidine kinase/phosphatase sensor for OmpR, modulates expression of ompF and ompC	EG10269	FUNCTION: MEMBER OF THE TWO-COMPONENT REGULATORY SYSTEM ENVZ/OMPR INVOLVED IN THE REGULATION OF OSMOREGULATION (GENES OMPF & OMPC). ENVZ FUNCTIONS AS A MEMBRANE-ASSOCIATED PROTEIN KINASE THAT PHOSPHORYLATES OMPR IN RESPONSE TO ENVIRONMENTAL SIGNALS. SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE. SIMILARITY: TO OTHER PROKARYOTIC SENSORY TRANSDUCTION HISTIDINE KINASES.