Score |
Strand | Gene name |
Blattner ID |
Description |
EcoCyc link |
SwissProt comment |
| 5.858078 | + | purM | b2499 | phosphoribosylaminoimidazole synthetase = AIR synthetase |
EG10798 |
CATALYTIC ACTIVITY: ATP + 5'-PHOSPHORIBOSYL-FORMYLGLYCINAMIDINE =
ADP + ORTHOPHOSPHATE + 5'-PHOSPHORIBOSYL-5-AMINOIMIDAZOLE.
PATHWAY: FIFTH STEP IN DE NOVO PURINE BIOSYNTHESIS.
SUBUNIT: HOMODIMER.
SUBCELLULAR LOCATION: CYTOPLASMIC.
SIMILARITY: TO OTHER BACTERIAL PURM.
|
 | | purN | b2500 | phosphoribosylglycinamide formyltransferase 1 |
EG10799 |
CATALYTIC ACTIVITY: 10-FORMYLTETRAHYDROFOLATE + 5'-PHOSPHO-
RIBOSYLGLYCINAMIDE = TETRAHYDROFOLATE + 5'-PHOSPHORIBOSYL-
N-FORMYLGLYCINAMIDE.
PATHWAY: THIRD STEP (FIRST OF TWO TRANSFORMYLATION REACTIONS)
IN DE NOVO PURINE BIOSYNTHESIS.
SUBUNIT: HOMODIMER.
SIMILARITY: TO OTHER GART FROM BACTERIA AND EUKARYOTES.
|
| 4.449966 | - | upp | b2498 | uracil phosphoribosyltransferase |
EG11332 |
CATALYTIC ACTIVITY: UMP + PYROPHOSPHATE = URACIL + 5-PHOSPHO-
ALPHA-D-RIBOSE 1-DIPHOSPHATE.
PATHWAY: PYRIMIDINE SALVAGE PATHWAY.
SUBUNIT: HOMOTRIMER.
INDUCTION: BY PYRIMIDINE STARVATION.
SIMILARITY: BELONGS TO THE UPRTASE FAMILY.
|
| | uraA | b2497 | uracil transport |
EG12129 |
FUNCTION: TRANSPORT OF URACIL IN THE CELL.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE.
SIMILARITY: BELONGS TO THE XANTHINE/URACIL PERMEASES FAMILY.
|
| | b2496 | b2496 | putative DNA replication factor |
EG14201 |
SIMILARITY: BELONGS TO THE DNAA FAMILY. STRONG, TO H.INFLUENZAE
HI1225.1.
|
| 2.852240 | - | yaiN | b0357 | putative alpha helix chain |
EG13296 |
SIMILARITY: TO E.COLI YOHL.
CAUTION: REF.1 SEQUENCE DIFFERS FROM THAT SHOWN DUE TO A
FRAMESHIFT IN POSITION 20.
|
| | adhC | b0356 | alcohol dehydrogenase class III; formaldehyde dehydrogenase, glutathione-dependent |
EG50010 |
FUNCTION: HAS HIGH FORMALDEHYDE DEHYDROGENASE ACTIVITY IN THE
PRESENCE OF GLUTATHIONE AND CATALYZES THE OXIDATION OF NORMAL
ALCOHOLS IN A REACTION THAT IS NOT GSH-DEPENDENT. IN ADDITION,
HEMITHIOLACETALS OTHER THAN THOSE FORMED FROM GSH, INCLUDING
OMEGA-THIOL FATTY ACIDS, ALSO ARE SUBSTRATES.
CATALYTIC ACTIVITY: ALCOHOL + NAD(+) = ALDEHYDE OR KETONE + NADH.
CATALYTIC ACTIVITY: FORMALDEHYDE + GLUTATHIONE + NAD(+) =
S-FORMYLGLUTATHIONE + NADH.
COFACTOR: REQUIRES ZINC FOR ITS ACTIVITY (4 IONS OF ZINC PER
DIMER).
SUBUNIT: HOMODIMER.
SUBCELLULAR LOCATION: CYTOPLASMIC.
SIMILARITY: BELONGS TO THE ZINC-CONTAINING ALCOHOL DEHYDROGENASE
FAMILY. CLASS-III SUBFAMILY.
CAUTION: REF.1 AND REF.4 SEQUENCE DIFFERS FROM THAT SHOWN DUE TO A
FRAMESHIFT IN POSITION 26.
|
| | yaiM | b0355 | putative esterase (EC 3.1.1.1) |
EG13295 |
SIMILARITY: STRONG, TO E.COLI YEIG AND H.INFLUENZAE HI0184.
SIMILARITY: STRONG, TO HUMAN ESTERASE D.
CAUTION: REF.1 SEQUENCE DIFFERS FROM THAT SHOWN DUE TO A
FRAMESHIFT IN POSITION 137.
|
| 2.714733 | - | sfhB | b2594 | suppressor of ftsH mutation |
EG12098 |
FUNCTION: RESPONSIBLE FOR SYNTHESIS OF PSEUDOURIDINE FROM URACIL
AT TWO POSITIONS IN 23S RIBOSOMAL RNA.
CATALYTIC ACTIVITY: URACIL + D-RIBOSE 5-PHOSPHATE = PSEUDOURIDINE
5'-PHOSPHATE + H(2)O.
SIMILARITY: BELONGS TO THE RLU FAMILY OF PSEUDOURIDINE SYNTHASES.
CAUTION: REF.4 SEQUENCE DIFFERS FROM THAT SHOWN DUE TO A
FRAMESHIFT.
|
| | yfiH | b2593 | orf, hypothetical protein |
EG12097 |
SIMILARITY: BELONGS TO THE UPF0124 FAMILY.
|
| | clpB | b2592 | heat shock protein |
EG10157 |
SUBUNIT: THOUGHT TO BE AN ATPASE SUBUNIT OF AN INTRACELLULAR
ATP-DEPENDENT PROTEASE.
INDUCTION: BY HEAT-SHOCK.
SIMILARITY: BELONGS TO THE CLPA/CLPB FAMILY.
|
| 2.594797 | + | yicP | b3665 | probable adenine deaminase (synthesis xanthine) |
EG11692 |
CATALYTIC ACTIVITY: ADENINE + H(2)O = HYPOXANTHINE + NH(3).
SIMILARITY: BELONGS TO THE ADENINE AMINASE FAMILY.
|
| 2.529681 | + | b2595 | b2595 | orf, hypothetical protein |
EG14222 |
SUBCELLULAR LOCATION: ATTACHED TO THE MEMBRANE BY A LIPID
ANCHOR (BY SIMILARITY).
SIMILARITY: BELONGS TO THE COML FAMILY OF LIPOPROTEINS. STRONG,
TO H.INFLUENZAE HI0177.
|
| | b2596 | b2596 | orf, hypothetical protein |
|
|
| | yfiA | b2597 | putative yhbH sigma 54 modulator |
EG11151 |
SIMILARITY: BELONGS TO THE SIGMA(54) MODULATION PROTEIN FAMILY.
STRONG, TO H.INFLUENZAE HI0257.
|
| | pheL | b2598 | leader peptide of chorismate mutase-P-prephenate dehydratase |
EG11271 |
FUNCTION: THIS PROTEIN IS INVOLVED IN CONTROL OF THE BIOSYNTHESIS
OF PHENYLALANINE.
|
| | pheA | b2599 | chorismate mutase-P and prephenate dehydratase |
EG10707 |
CATALYTIC ACTIVITY: CHORISMATE = PREPHENATE.
CATALYTIC ACTIVITY: PREPHENATE = PHENYLPYRUVATE + H(2)O + CO(2).
PATHWAY: L-PHENYLALANINE BIOSYNTHESIS.
SUBCELLULAR LOCATION: CYTOPLASMIC.
SIMILARITY: TO OTHER PDT ENZYMES OR DOMAINS.
|
| 2.337307 | - | lysP | b2156 | lysine-specific permease |
EG11337 |
FUNCTION: PERMEASE THAT IS INVOLVED IN THE TRANSPORT ACROSS THE
CYTOPLASMIC MEMBRANE OF LYSINE.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE.
INDUCTION: HIGH, IN ANAEROBIC MEDIA OF LOW PH, CONTAINING LYSINE.
SIMILARITY: BELONGS TO THE AMINO ACID PERMEASE FAMILY.
|
| 2.329805 | - | dacA | b0632 | D-alanyl-D-alanine carboxypeptidase, fraction A; penicillin-binding protein 5 |
EG10201 |
FUNCTION: REMOVES C-TERMINAL D-ALANYL RESIDUES FROM SUGAR-PEPTIDE
CELL WALL PRECURSORS.
CATALYTIC ACTIVITY: D-ALANYL-D-ALANINE + H(2)O = 2 D-ALANINE.
PATHWAY: FINAL STAGES IN PEPTIDOGLYCAN SYNTHESIS.
SUBCELLULAR LOCATION: INNER MEMBRANE-ASSOCIATED. N-TERMINAL
LIES IN THE PERIPLASMIC SPACE.
MISCELLANEOUS: THE MUTANT DACA1191 IS STILL BINDING PENICILLIN,
BUT IS BLOCKED IN THE RELEASE OF THE BOUND PENICILLOYL MOIETY; THE
MUTANT ALSO FAILS TO CATALYSE THE D-ALANINE CARBOXYPEPTIDASE
REACTION AS THE HYDROLYSIS OF THE ACYL-ENZYME FORMED WITH
SUBSTRATE IS ALSO BLOCKED AND THE ACYL-ENZYME ACCUMULATES.
SIMILARITY: BELONGS TO PEPTIDASE FAMILY S11; ALSO KNOWN AS THE
D-ALANYL-D-ALANINE CARBOXYPEPTIDASE 1 FAMILY.
|
| | ybeD | b0631 | orf, hypothetical protein |
EG11592 |
SIMILARITY: STRONG, TO H.INFLUENZAE HI0028.
|
| 1.921946 | + | tolC | b3035 | outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes |
EG11009 |
FUNCTION: REQUIRED FOR PROPER EXPRESSION OF OUTER MEMBRANE PROTEIN
GENES SUCH AS OMPF, NMPC, PROTEIN 2, HEMOLYSIN, COLICIN V, OR
COLICIN E1. MAY BE SPECIALIZED FOR SIGNAL SEQUENCE INDEPENDENT,
EXTRACELLULAR SECRETION IN GRAM-NEGATIVE BACTERIA.
SUBCELLULAR LOCATION: OUTER MEMBRANE.
SIMILARITY: BELONGS TO THE PRTF FAMILY OF SECRETION PROTEINS.
CAUTION: REF.2 SEQUENCE WAS EXTENSIVELY CORRECTED BY REF.1.
|
| | ygiA | b3036 | orf, hypothetical protein |
|
|
| | ygiB | b3037 | orf, hypothetical protein |
EG11164 |
|
| | ygiC | b3038 | putative synthetase/amidase |
EG11165 |
SIMILARITY: STRONG, TO H.INFLUENZAE HI0929.
SIMILARITY: STRONG, TO THE N-TERMINAL OF E.COLI GSP AND TO E.COLI
YJFC.
|
| 1.698022 | + | yjfK | b4183 | orf, hypothetical protein |
EG12486 |
|
| | yjfL | b4184 | orf, hypothetical protein |
EG12487 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
|
| | yjfM | b4185 | orf, hypothetical protein |
EG12488 |
|
| | yjfC | b4186 | putative synthetase/amidase |
EG11812 |
SIMILARITY: STRONG, TO THE N-TERMINAL OF E.COLI GSP AND TO E.COLI
YGIC.
|
| | aidB | b4187 | putative acyl coenzyme A dehydrogenase |
EG11811 |
INDUCTION: BY ALKYLATING AGENTS.
SIMILARITY: BELONGS TO THE ACYL-COA DEHYDROGENASES FAMILY.
|
| 1.647999 | + | ompG | b1319 | outer membrane protein |
EG13428 |
FUNCTION: FORMS CHANNELS FUNCTIONALLY LARGER THAN THOSE OF
CLASSICAL PORINS.
SUBUNIT: MONOMER.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. OUTER MEMBRANE.
|
| 1.625030 | + | yaiC | b0385 | orf, hypothetical protein |
EG11257 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
SIMILARITY: BELONGS TO THE YAIC / YFIN (E.COLI), YHCK (B.SUBTILIS)
FAMILY.
|
| 1.512307 | - | yijP | b3955 | orf, hypothetical protein |
EG11914 |
FUNCTION: PLAYS A ROLE IN THE PATHOGENESIS OF E.COLI MENINGITIS.
REQUIRED FOR INVASION OF E.COLI K1 INTO BRAIN MICROVASCULAR
ENDOTHELIAL CELLS (BMEC). CONTRIBUTES TO E.COLI TRAVERSAL ACROSS
THE BLOOD-BRAIN BARRIER.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (PROBABLE).
SIMILARITY: BELONGS TO THE UPF0141 FAMILY.
|
| 1.457196 | - | gltX | b2400 | glutamate tRNA synthetase, catalytic subunit |
EG10407 |
CATALYTIC ACTIVITY: ATP + L-GLUTAMATE + TRNA(GLU) = AMP +
PYROPHOSPHATE + L-GLUTAMYL-TRNA(GLU).
SUBUNIT: MONOMER.
SUBCELLULAR LOCATION: CYTOPLASMIC.
MISCELLANEOUS: THIS IS THE SMALLEST AMINOACYL-TRNA SYNTHETASE OF
E.COLI; IT DOES NOT BIND GLUTAMATE IN THE ABSENCE OF COGNATE TRNA,
WHICH IS THEREFORE REQUIRED FOR ACTIVATION OF THE AMINO ACID
SUBSTRATE.
SIMILARITY: BELONGS TO CLASS-I AMINOACYL-TRNA SYNTHETASE FAMILY.
|
| 1.431696 | + | add | b1623 | adenosine deaminase |
EG10030 |
CATALYTIC ACTIVITY: ADENOSINE + H(2)O = INOSINE + NH(3) (ALSO ACTS
ON DEOXYADENOSINE).
SIMILARITY: BELONGS TO THE ADENOSINE AND AMP DEAMINASES FAMILY.
|
| 1.416113 | + | yhhF | b3465 | orf, hypothetical protein |
EG10343 |
SIMILARITY: STRONG, TO H.INFLUENZAE HI0767.
|
| | yhhL | b3466 | orf, hypothetical protein |
EG12212 |
|
| 1.402064 | + | dnaB | b4052 | replicative DNA helicase; part of primosome |
EG10236 |
FUNCTION: PARTICIPATES IN INITIATION AND ELONGATION DURING
CHROMOSOME REPLICATION; IT EXHIBITS DNA-DEPENDENT ATPASE ACTIVITY
AND CONTAINS DISTINCT ACTIVE SITES FOR ATP BINDING, DNA BINDING,
AND INTERACTION WITH DNAC PROTEIN, PRIMASE, AND OTHER PREPRIMING
PROTEINS.
SUBUNIT: HOMOHEXAMER.
SIMILARITY: BELONGS TO THE DNAB SUBFAMILY OF HELICASES.
|
| | alr | b4053 | alanine racemase 1 |
EG10001 |
FUNCTION: CELL WALL FORMATION.
CATALYTIC ACTIVITY: L-ALANINE = D-ALANINE.
COFACTOR: PYRIDOXAL PHOSPHATE.
PATHWAY: ALONG WITH D-ALANINE-D-ALANINE LIGASE, IT MAKES UP THE
D-ALANINE BRANCH OF THE PEPTIDOGLYCAN BIOSYNTHETIC ROUTE.
SUBUNIT: MONOMER.
SIMILARITY: BELONGS TO THE ALANINE RACEMASE FAMILY.
|
| 1.364593 | - | ftsY | b3464 | cell division membrane protein |
EG10346 |
FUNCTION: FUNCTIONAL HOMOLOG OF SRP RECEPTOR. PROBABLY INVOLVED IN
THE RECEPTION AND INSERTION OF A SUBSET OF PROTEINS AT THE
CYTOPLASMIC MEMBRANE.
SUBCELLULAR LOCATION: INNER MEMBRANE-ASSOCIATED.
SIMILARITY: BELONGS TO THE SRP FAMILY OF GTP-BINDING PROTEINS.
|
| | ftsE | b3463 | ATP-binding component of a membrane-associated complex involved in cell division |
EG10340 |
FUNCTION: NOT KNOWN. IS CODED IN AN OPERON ESSENTIAL FOR
CELL DIVISION.
SIMILARITY: BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY
(ABC TRANSPORTERS).
|
| | ftsX | b3462 | cell division membrane protein |
EG10345 |
FUNCTION: NOT KNOWN. IS CODED IN AN OPERON ESSENTIAL FOR
CELL DIVISION.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
SIMILARITY: BELONGS TO THE FTSX FAMILY.
|
| 1.295510 | - | b2760 | b2760 | orf, hypothetical protein |
EG13119 |
|
| | ygcK | b2759 | orf, hypothetical protein |
EG13118 |
|
| | b2758 | b2758 | orf, hypothetical protein |
EG13117 |
|
| | b2757 | b2757 | orf, hypothetical protein |
EG13116 |
|
| | b2756 | b2756 | orf, hypothetical protein |
EG13115 |
|
| | b2755 | b2755 | orf, hypothetical protein |
EG13114 |
|
| | ygbF | b2754 | orf, hypothetical protein |
EG12845 |
|
| 1.190128 | - | b0868 | b0868 | putative nucleotide di-P-sugar epimerase or dehydratase |
|
|
| 1.165458 | - | celB | b1737 | PEP-dependent phosphotransferase enzyme II for cellobiose, arbutin, and salicin |
EG10141 |
FUNCTION: THIS IS A COMPONENT OF THE PHOSPHOENOLPYRUVATE-DEPENDENT
SUGAR PHOSPHOTRANSFERASE SYSTEM (PTS), A MAJOR CARBOHYDRATE ACTIVE
-TRANSPORT SYSTEM. THE IICD DOMAINS CONTAIN THE SUGAR BINDING SITE
AND THE TRANSMEMBRANE CHANNEL; THE IIA DOMAIN CONTAINS THE PRIMARY
PHOSPHORYLATION SITE (THE DONOR IS PHOSPHO-HPR); IIA TRANSFERS ITS
PHOSPHORYL GROUP TO THE IIB DOMAIN WHICH FINALLY TRANSFERS IT TO
THE SUGAR.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE.
SIMILARITY: CONTAINS A PTS EIIC DOMAIN.
|
| | celC | b1736 | PEP-dependent phosphotransferase enzyme III for cellobiose, arbutin, and salicin |
EG10142 |
FUNCTION: THIS IS A COMPONENT OF THE PHOSPHOENOLPYRUVATE-DEPENDENT
SUGAR PHOSPHOTRANSFERASE SYSTEM (PTS), A MAJOR CARBOHYDRATE ACTIVE
-TRANSPORT SYSTEM. THE IICD DOMAINS CONTAIN THE SUGAR BINDING SITE
AND THE TRANSMEMBRANE CHANNEL; THE IIA DOMAIN CONTAINS THE PRIMARY
PHOSPHORYLATION SITE (THE DONOR IS PHOSPHO-HPR); IIA TRANSFERS ITS
PHOSPHORYL GROUP TO THE IIB DOMAIN WHICH FINALLY TRANSFERS IT TO
THE SUGAR.
CATALYTIC ACTIVITY: PROTEIN N-PHOSPHOHISTIDINE + SUGAR =
PROTEIN HISTIDINE + SUGAR PHOSPHATE.
SUBCELLULAR LOCATION: CYTOPLASMIC.
SIMILARITY: CONTAINS A PTS EIIA DOMAIN.
|
| | celD | b1735 | negative transcriptional regulator of cel operon |
EG10143 |
FUNCTION: REPRESSOR FOR THE CELABCF OPERON.
SIMILARITY: BELONGS TO THE ARAC/XYLS FAMILY OF TRANSCRIPTIONAL
REGULATORS.
|
| | celF | b1734 | phospho-beta-glucosidase; cryptic |
EG10144 |
FUNCTION: HYDOLYZES A WIDE VARIETY OF P-BETA-GLUCOSIDES INCLUDING
CELLUBIOSE-6P, SALICIN-6P, ARBUTIN-6P, GENTIOBIOSE-6P, METHYL-
BETA-GLUCOSIDE-6P AND P-NITROPHENYL-BETA-D-GLUCOPYRANOSIDE-6P.
CATALYTIC ACTIVITY: 6-PHOSPHO-BETA-D-GLUCOSIDE-(1,4)-D-GLUCOSE +
H(2)O = D-GLUCOSE 6-PHOSPHATE + GLUCOSE.
COFACTOR: NAD AND A DIVALENT METAL ION. MANGANESE, COBALT AND
NICKEL IONS ENHANCE ACTIVITY WHEREAS MAGNESIUM, CALCIUM,
STRONTIUM AND ZINC IONS DO NOT.
PATHWAY: FERMENTATION OF THE BETA-GLUCOSIDES CELLOBIOSE,
ARBUTIN, AND SALICIN.
SIMILARITY: BELONGS TO FAMILY 4 OF GLYCOSYL HYDROLASES.
CAUTION: REF.1 AND REF.4 SEQUENCES DIFFER FROM THAT SHOWN IN
POSITIONS 371 ONWARD DUE TO NUMBER OF FRAMESHIFTS AS WELL AS OTHER
SEQUENCE ERRORS.
|
| | ydjC | b1733 | orf, hypothetical protein |
EG12198 |
INDUCTION: BY NICKEL.
|
| 1.091644 | + | ygiL | b3043 | putative fimbrial-like protein |
EG12363 |
SIMILARITY: BELONGS TO THE FIMA/PAPA FAMILY OF FIMBRIA PROTEINS.
|
| 1.086183 | - | yqiE | b3034 | orf, hypothetical protein |
EG12184 |
CATALYTIC ACTIVITY: ADP-RIBOSE + H(2)O = AMP + D-RIBOSE 5-
PHOSPHATE.
COFACTOR: REQUIRES DIVALENT IONS: MAGNESIUM, MANGANESE OR ZINC.
SIMILARITY: BELONGS TO THE NUDIX HYDROLASE FAMILY. NUDF SUBFAMILY.
|
| | yqiB | b3033 | putative enzyme |
EG12185 |
|
| | icc | b3032 | regulator of lacZ |
EG12187 |
FUNCTION: AFFECTS THE EXPRESSION OF THE LACZ GENE.
SIMILARITY: TO SYNECHOCOCCUS PCC 6301 HYPOTHETICAL 16.8 KDA
PROTEIN IN 16S RRNA GENE REGION (AC P05675).
|
| | yqiA | b3031 | orf, hypothetical protein |
EG12186 |
|
| | parE | b3030 | DNA topoisomerase IV subunit B |
EG10687 |
FUNCTION: TOPOISOMERASE IV IS ESSENTIAL FOR CHROMOSOME
SEGREGATION. IT HAS RELAXATION OF SUPERCOILED DNA ACTIVITY.
PERFORMS THE DECATENATION EVENTS REQUIRED DURING THE REPLICATION
OF A CIRCULAR DNA MOLECULE.
SUBUNIT: COMPOSED OF TWO SUBUNITS: PARC AND PARE.
SIMILARITY: BELONGS TO THE TYPE II TOPOISOMERASE FAMILY.
|
| 1.073453 | + | metE | b3829 | tetrahydropteroyltriglutamate methyltransferase |
EG10584 |
FUNCTION: CATALYZES THE TRANSFER OF A METHYL GROUP FROM 5-
METHYLTETRAHYDROFOLATE TO HOMOCYSTEINE RESULTING IN METHIONINE
FORMATION.
CATALYTIC ACTIVITY: 5-METHYLTETRAHYDROPTEROYLTRI-L-GLUTAMATE +
L-HOMOCYSTEINE = TETRAHYDROPTEROYLTRI-L-GLUTAMATE + L-METHIONINE.
COFACTOR: ZINC; BINDS ONE MOLE PER SUBUNIT.
PATHWAY: TERMINAL STEP IN THE DE NOVO BIOSYNTHESIS OF METHIONINE.
SUBUNIT: MONOMER.
MISCELLANEOUS: HAS AN ABSOLUTE REQUIREMENT FOR A POLYGLUTAMYLATED
FOLATE AS SUBSTRATE. ITS ACTIVITY DEPENDS ON PHOSPHATE ANIONS AND
DIVALENT CATIONS.
SIMILARITY: BELONGS TO THE VITAMIN-B12 INDEPENDENT METHIONINE
SYNTHASE FAMILY.
|
| 1.050364 | - | qor | b4051 | quinone oxidoreductase |
EG11492 |
CATALYTIC ACTIVITY: NADPH + QUINONE = NADP(+) + SEMIQUINONE.
SIMILARITY: BELONGS TO THE ZINC-CONTAINING ALCOHOL DEHYDROGENASE
FAMILY. QUINONE OXIDOREDUCTASE SUBFAMILY.
|
| 1.041504 | + | yihK | b3871 | putative GTP-binding factor |
EG11837 |
FUNCTION: NOT KNOWN; PROBABLY INTERACTS WITH THE RIBOSOMES IN A
GTP DEPENDENT MANNER. GTPASE THAT MEDIATES INTERACTIONS BETWEEN
ENTEROPATHOGENIC ESCHERICHIA COLI (EPEC) AND EPITHELIAL CELLS.
PTM: PHOSPHORYLATED ON TYROSINE.
SIMILARITY: BELONGS TO THE GTP-BINDING ELONGATION FACTOR FAMILY.
TYPA SUBFAMILY.
|
| 1.007750 | + | b2651 | b2651 | orf, hypothetical protein |
|
|
| 0.901004 | - | yohI | b2140 | putative regulator protein |
EG12022 |
SIMILARITY: BELONGS TO THE UPF0034 (NIFR3/SMM1) FAMILY. STRONG, TO
H.INFLUENZAE HI0270.
|
| 0.868338 | - | b2462 | b2462 | orf, hypothetical protein |
EG14192 |
FUNCTION: MAY BE INVOLVED IN THE FORMATION OF A SPECIFIC
MICROCOMPARTIMENT IN THE CELL IN WHICH THE METABOLISM OF
POTENTIALLY TOXIC BY-PRODUCTS TAKES PLACE.
PATHWAY: ETHANOLAMINE UTILIZATION.
SIMILARITY: DISTANTLY RELATED TO THE CCHA/CCMK/CSOS1/PDUA FAMILY.
|
| | b2461 | b2461 | orf, hypothetical protein |
EG14191 |
PATHWAY: ETHANOLAMINE UTILIZATION.
SIMILARITY: BELONGS TO THE EUTP/PDUV FAMILY.
|
| | b2460 | b2460 | orf, hypothetical protein |
EG14190 |
PATHWAY: ETHANOLAMINE UTILIZATION.
|
| | b2459 | b2459 | orf, hypothetical protein |
EG14189 |
FUNCTION: CONVERTS CNB12 TO ADOB12 (BY SIMILARITY).
CATALYTIC ACTIVITY: ATP + COB(I)ALAMIN + H(2)O = ORTHOPHOSPHATE +
PYROPHOSPHATE + ADENOSYLCOBALAMIN.
PATHWAY: ETHANOLAMINE UTILIZATION.
|
| | eutI | b2458 | ethanolamine utilization; homolog of Salmonella acetyl/butyryl P transferase |
EG14188 |
PATHWAY: ETHANOLAMINE UTILIZATION.
SIMILARITY: BELONGS TO THE PHOSPHATE ACETYLTRANSFERASE AND
BUTYRYLTRANSFERASE FAMILY.
|
| | cchA | b2457 | detox protein |
EG14187 |
FUNCTION: MAY BE INVOLVED IN THE FORMATION OF A SPECIFIC
MICROCOMPARTIMENT IN THE CELL IN WHICH THE METABOLISM OF
POTENTIALLY TOXIC BY-PRODUCTS TAKES PLACE.
PATHWAY: ETHANOLAMINE UTILIZATION.
SIMILARITY: BELONGS TO THE CCHA/CCMK/CSOS1/PDUA FAMILY.
|
| | cchB | b2456 | detox protein |
EG14186 |
FUNCTION: MAY BE INVOLVED IN THE FORMATION OF A SPECIFIC
MICROCOMPARTIMENT IN THE CELL IN WHICH THE METABOLISM OF
POTENTIALLY TOXIC BY-PRODUCTS TAKES PLACE.
PATHWAY: ETHANOLAMINE UTILIZATION.
SIMILARITY: TO CYANOBACTERIAL CARBON DIOXIDE CONCENTRATING
MECHANISM PROTEIN CCML.
|
| | eutE | b2455 | ethanolamine utilization; similar to acetaldehyde dehydrogenase |
EG14185 |
FUNCTION: MAY ACT AS AN ACETALDEHYDE DEHYDROGENASE THAT CONVERTS
ACETALDEHYDE INTO ACETYL-COA.
PATHWAY: ETHANOLAMINE UTILIZATION.
SIMILARITY: TO THE N-TERMINAL OF E.COLI AND C.ACETOBUTYLICUM ADHE.
|
| | eutJ | b2454 | ethanolamine utilization; homolog of Salmonella gene |
EG14184 |
PATHWAY: ETHANOLAMINE UTILIZATION.
|
| | eutG | b2453 | ethanolamine utilization; homolog of Salmonella enzyme, similar to iron-containing alcohol dehydrogenase |
EG14183 |
FUNCTION: MAY ACT ON THE ACETALDEHYDE PRODUCED FROM THE
DEGRADATION OF ETHANOLAMINE.
PATHWAY: ETHANOLAMINE UTILIZATION.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
SIMILARITY: BELONGS TO THE IRON-CONTAINING ALCOHOL DEHYDROGENASE
FAMILY.
|
| 0.864947 | - | yeeF | b2014 | putative amino acid/amine transport protein |
EG11896 |
FUNCTION: PROBABLE AMINO-ACID OR METABOLITE TRANSPORT PROTEIN.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE
(POTENTIAL).
SIMILARITY: BELONGS TO THE AMINO ACID PERMEASE FAMILY.
|
| 0.851042 | - | yddG | b1473 | orf, hypothetical protein |
EG12713 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
|
| 0.839303 | + | ybhH | b0769 | orf, hypothetical protein |
EG13664 |
SIMILARITY: TO B.SUBTILIS YRAM.
|
| | ybhI | b0770 | putative membrane pump protein |
EG13665 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE
(PROBABLE).
SIMILARITY: BELONGS TO THE NADC/P/PHO87 FAMILY OF TRANSPORTERS.
SODIT1 SUBFAMILY. STRONG, TO H.INFLUENZAE HI0020.
|
| 0.838413 | - | yjgA | b4234 | putative alpha helix protein |
EG11410 |
SIMILARITY: STRONG, TO H.INFLUENZAE HI1151.
|
| 0.811745 | + | b1964 | b1964 | putative outer membrane protein |
EG14042 |
SUBUNIT: HOMOTRIMER (BY SIMILARITY).
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. OUTER MEMBRANE
(BY SIMILARITY).
SIMILARITY: BELONGS TO THE OMPC/PHOE FAMILY OF PORINS.
CAUTION: THIS IS A CONCEPTUAL TRANSLATION, AN IN-FRAME STOP CODON
WAS READ OVER IN POSITION 162 AND TWO POTENTIAL FRAMESHIFTS WERE
CORRECTED.
|
| | b1965 | b1965 | orf, hypothetical protein |
|
|
| | b1966 | b1966 | putative outer membrane protein |
|
|
| 0.811275 | + | b2360 | b2360 | orf, hypothetical protein |
EG14139 |
|
| | b2361 | b2361 | orf, hypothetical protein |
EG14140 |
|
| | b2362 | b2362 | orf, hypothetical protein |
|
|
| | b2363 | b2363 | orf, hypothetical protein |
|
|