Score |
Strand | Gene name |
Blattner ID |
Description |
EcoCyc link |
SwissProt comment |
| 1.574692 | + | ybhJ | b0771 | putative enzyme |
EG13666 |
SIMILARITY: BELONGS TO THE ACONITASE/IPM ISOMERASE FAMILY.
|
| 1.197786 | - | yrdD | b3283 | putative DNA topoisomerase |
EG12841 |
SIMILARITY: STRONG, TO H.INFLUENZAE HI0656.1.
SIMILARITY: STRONG, TO THE C-TERMINUS OF SOME BACTERIAL
TOPOISOMERASE I.
SIMILARITY: SOME, TO M.JANNASCHII MJ0664.
|
 | | yrdC | b3282 | orf, hypothetical protein |
EG12840 |
SIMILARITY: BELONGS TO THE SUA5/YRDC/YCIO/YWLC FAMILY. STRONG, TO
H.INFLUENZAE HI0656.
|
| | aroE | b3281 | dehydroshikimate reductase |
EG10077 |
CATALYTIC ACTIVITY: SHIKIMATE + NADP(+) = 5-DEHYDROSHIKIMATE +
NADPH.
PATHWAY: FOURTH STEP IN THE BIOSYNTHESIS OF CHORISMATE WITHIN THE
BIOSYNTHESIS OF AROMATIC AMINO ACIDS (THE SHIKIMATE PATHWAY).
SUBUNIT: MONOMER.
SIMILARITY: BELONGS TO THE SHIKIMATE DEHYDROGENASE FAMILY.
|
| | yrdB | b3280 | orf, hypothetical protein |
EG12839 |
|
| 0.493908 | - | b1957 | b1957 | orf, hypothetical protein |
EG14307 |
|
| 0.401045 | - | ribE | b1662 | riboflavin synthase, alpha chain |
EG11406 |
FUNCTION: RIBOFLAVIN SYNTHASE IS A BIFUNCTIONAL ENZYME COMPLEX
CATALYZING THE FORMATION OF RIBOFLAVIN FROM 5-AMINO-6-(1'-D)-
RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE AND L-3,4-DIHYDROHY-2-
BUTANONE-4-PHOSPHATE VIA 6,7-DIMETHYL-8-LUMAZINE. THE ALPHA
SUBUNIT CATALYZES THE DISMUTATION OF 6,7-DIMETHYL-8-LUMAZINE TO
RIBOFLAVIN AND 5-AMINO-6-(1'-D)-RIBITYL-AMINO-2,4(1H,3H)-
PYRIMIDINEDIONE.
CATALYTIC ACTIVITY: 2 6,7-DIMETHYL-8-(1'-D-RIBITYL)LUMAZINE =
RIBOFLAVIN + 4-(1-D-RIBITYLAMINO)-5-AMINO-2,6-DIHYDROXYPYRIMIDINE.
COFACTOR: FLAVOPROTEIN.
PATHWAY: FINAL STEPS OF RIBOFLAVIN SYNTHESIS.
SUBUNIT: OLIGOMER THAT CONSIST OF 3 ALPHA SUBUNITS AND 60 BETA
SUBUNITS (BY SIMILARITY).
DOMAIN: COMPOSED OF TWO HOMOLOGOUS DOMAINS.
SIMILARITY: TO BIOLUMINESCENCE ANTENNA PROTEINS LUXY (YFP) AND
LUXL (LUMP).
|
| 0.376776 | + | caiF | b0034 | transcriptional regulator of cai operon |
EG13451 |
FUNCTION: POTENTIAL TRANSCRIPTIONAL ACTIVATOR OF CARNITINE
METABOLISM.
|
| 0.308574 | + | crcA | b0622 | orf, hypothetical protein |
EG12180 |
FUNCTION: NOT KNOWN; OVERPRODUCTION LEADS TO CAMPHOR RESISTANCE
AND CHROMOSOME CONDENSATION.
CAUTION: REF.3 SEQUENCE DIFFERS FROM THAT SHOWN DUE TO THREE
FRAMESHIFTS.
|
| 0.269781 | + | b3122 | b3122 | orf, hypothetical protein |
|
|
| 0.228800 | + | tdcR | b3119 | threonine dehydratase operon activator protein |
EG10992 |
FUNCTION: PROBABLE TRANS-ACTING POSITIVE ACTIVATOR FOR THE TDC
OPERON.
|
| 0.223123 | + | smpB | b2620 | small protein B |
EG11782 |
FUNCTION: BINDS SPECIFICALLY TO THE SSRA RNA (TMRNA) AND IS
REQUIRED FOR STABLE ASSOCIATION OF SSRA WITH RIBOSOMES.
SUBCELLULAR LOCATION: CYTOPLASMIC (POTENTIAL).
SIMILARITY: BELONGS TO THE SSRP FAMILY.
|
| 0.221639 | + | apt | b0469 | adenine phosphoribosyltransferase |
EG10051 |
FUNCTION: CATALYSES A SALVAGE REACTION RESULTING IN THE FORMATION
OF AMP, THAT IS ENERGICALLY LESS COSTLY THAN DE NOVO SYNTHESIS.
CATALYTIC ACTIVITY: AMP + PYROPHOSPHATE = ADENINE + 5-PHOSPHO-
ALPHA-D-RIBOSE 1-DIPHOSPHATE.
PATHWAY: PURINE SALVAGE.
SUBUNIT: HOMODIMER.
SUBCELLULAR LOCATION: CYTOPLASMIC.
SIMILARITY: BELONGS TO THE PURINE/PYRIMIDINE
PHOSPHORIBOSYLTRANSFERASE FAMILY.
|
| | dnaX | b0470 | DNA polymerase III, tau and gamma subunits; DNA elongation factor III |
EG10245 |
FUNCTION: DNA POLYMERASE III IS A COMPLEX, MULTICHAIN ENZYME
RESPONSIBLE FOR MOST OF THE REPLICATIVE SYNTHESIS IN BACTERIA.
THIS DNA POLYMERASE ALSO EXHIBITS 3' TO 5' EXONUCLEASE ACTIVITY.
FUNCTION: THE TAU CHAIN SERVES AS A SCAFFOLD TO HELP IN THE
DIMERIZATON OF THE CORE COMPLEX.
FUNCTION: THE GAMMA CHAIN SEEMS TO INTERACT WITH THE DELTA
SUBUNIT TO TRANSFER THE BETA SUBUNIT ON THE DNA.
CATALYTIC ACTIVITY: N DEOXYNUCLEOSIDE TRIPHOSPHATE =
N PYROPHOSPHATE + DNA(N).
SUBUNIT: CONTAINS A CORE (COMPOSED OF ALPHA, EPSILON, AND THETA
CHAINS) THAT ASSOCIATES WITH A TAU SUBUNIT WHICH ALLOW THE CORE
DIMERIZATION TO FORM THE POLIII' COMPLEX. POLIII' ASSOCIATES WITH
THE GAMMA COMPLEX (COMPOSED OF CHAINS GAMMA, DELTA, DELTA', PSI,
AND CHI) AND WITH THE BETA CHAIN. THE FINAL COMPOSITION OF THE
COMPLEX IS: (ALPHA,EPSILON,THETA)[2]-TAU[2]-(GAMMA,DELTA,DELTA',
PSI,CHI)[2]-BETA[4].
ALTERNATIVE PRODUCTS: THE PRODUCTION OF THE TWO PROTEIN PRODUCTS
FROM THIS REGION IS DUE TO PROGRAMMED RIBOSOMAL FRAMESHIFTING.
SIMILARITY: PARTIAL TO PHAGE T4 DNA POLYMERASE ACCESSORY PROTEIN
44 AND TO HUMAN ACTIVATOR 1, 37 AND 40 KDA SUBUNITS.
|
| | ybaB | b0471 | orf, hypothetical protein |
EG11100 |
SIMILARITY: BELONGS TO THE UPF0133 FAMILY.
|
| | recR | b0472 | recombination and repair |
EG10834 |
FUNCTION: MAY PLAY A ROLE IN DNA REPAIR. IT SEEMS TO BE INVOLVED
IN AN RECBC-INDEPENDENT RECOMBINATIONAL PROCESS OF DNA REPAIR. IT
MAY ACT WITH RECF AND RECO.
SIMILARITY: BELONGS TO THE RECR FAMILY.
|
| | htpG | b0473 | chaperone Hsp90, heat shock protein C 62.5 |
EG10461 |
FUNCTION: MOLECULAR CHAPERONE. HAS ATPASE ACTIVITY.
SIMILARITY: BELONGS TO THE HEAT SHOCK PROTEIN 90 FAMILY.
|
| 0.208744 | + | yaiU | b0374 | putative flagellin structural protein |
EG13606 |
|
| | yaiV | b0375 | orf, hypothetical protein |
EG13607 |
|
| 0.201941 | + | fabH | b1091 | 3-oxoacyl-[acyl-carrier-protein] synthase III; acetylCoA ACP transacylase |
EG10277 |
FUNCTION: CATALYZES THE CONDENSATION REACTION OF FATTY ACID
SYNTHESIS BY THE ADDITION TO AN ACYL ACCEPTOR OF TWO CARBONS
FROM MALONYL-ACP. KAS III CATALYZES THE FIRST CONDENSATION
REACTION WHICH INITIATES FATTY ACID SYNTHESIS AND MAY THEREFORE
PLAY A ROLE IN GOVERNING THE TOTAL RATE OF FATTY ACID PRODUCTION.
POSSESSES BOTH ACETOACETYL-ACP SYNTHASE AND ACETYL TRANSACYLASE
ACTIVITIES.
CATALYTIC ACTIVITY: ACYL-[ACYL-CARRIER PROTEIN] + MALONYL-[ACYL-
CARRIER PROTEIN] = 3-OXOACYL-[ACYL-CARRIER PROTEIN] + CO(2) +
[ACYL-CARRIER PROTEIN].
PATHWAY: FATTY ACID BIOSYNTHESIS.
SUBUNIT: MONOMER.
SIMILARITY: BELONGS TO THE FABH FAMILY.
|
| | fabD | b1092 | malonyl-CoA-[acyl-carrier-protein] transacylase |
EG11317 |
CATALYTIC ACTIVITY: MALONYL-COA + [ACYL-CARRIER PROTEIN] = COA
+ MALONYL-[ACYL-CARRIER PROTEIN].
PATHWAY: FATTY ACID BIOSYNTHESIS.
SIMILARITY: SIGNIFICANT, TO SEVERAL OTHER PROTEINS WITH
TRANSACYLASE ACTIVITY.
|
| | fabG | b1093 | 3-oxoacyl-[acyl-carrier-protein] reductase |
EG11318 |
CATALYTIC ACTIVITY: (3R)-3-HYDROXYACYL-[ACYL-CARRIER PROTEIN] +
NADP(+) = 3-OXOACYL-[ACYL-CARRIER PROTEIN] + NADPH.
PATHWAY: FIRST REDUCTION STEP IN THE FATTY ACID BIOSYNTHESIS
PATHWAY.
SIMILARITY: BELONGS TO THE SHORT-CHAIN DEHYDROGENASES/REDUCTASES
(SDR) FAMILY.
|
| 0.198397 | + | yaeD | b0200 | putative phosphatase |
EG11736 |
SIMILARITY: STRONG, TO H.INFLUENZAE HI0621.1.
SIMILARITY: TO M.JANNASCHII MJ0015.
SIMILARITY: TO THE N-TERMINAL PART OF E.COLI HISB, THE HISTIDINOL
PHOSPHATE PHOSPHATASE DOMAIN.
|
| 0.195618 | + | ybaO | b0447 | putative LRP-like transcriptional regulator |
EG13218 |
SIMILARITY: BELONGS TO THE ASNC FAMILY OF TRANSCRIPTIONAL
REGULATORS.
|
| | mdlA | b0448 | ATP-binding component of a transport system |
EG11622 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE
(POTENTIAL).
SIMILARITY: BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY
(ABC TRANSPORTERS). MDR SUBFAMILY.
CAUTION: REF.1 SEQUENCE DIFFERS FROM THAT SHOWN DUE TO A
FRAMESHIFT THAT FUSES MDLA AND MDLB.
|
| | mdlB | b0449 | putative ATP-binding component of a transport system |
EG14374 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE
(POTENTIAL).
SIMILARITY: BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY
(ABC TRANSPORTERS). MDR SUBFAMILY.
CAUTION: REF.1 SEQUENCE DIFFERS FROM THAT SHOWN DUE TO A
FRAMESHIFT THAT FUSES MDLA AND MDLB.
|
| 0.181151 | + | pyrF | b1281 | orotidine-5'-phosphate decarboxylase |
EG10809 |
CATALYTIC ACTIVITY: OROTIDINE-5'-PHOSPHATE = UMP + CO(2).
PATHWAY: SIXTH AND LAST STEP IN THE BIOSYNTHESIS OF PYRIMIDINES.
SUBUNIT: HOMODIMER.
SIMILARITY: BELONGS TO THE OMP DECARBOXYLASE FAMILY.
|
| | yciH | b1282 | orf, hypothetical protein |
EG11128 |
SIMILARITY: BELONGS TO THE SUI1 FAMILY.
|
| 0.177453 | + | yijE | b3943 | orf, hypothetical protein |
EG11902 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (PROBABLE).
SIMILARITY: BELONGS TO THE EAMA TRANSPORTER FAMILY.
|
| 0.175581 | + | wecD | b3790 | orf, hypothetical protein |
EG11455 |
FUNCTION: TRANSAMINASE CONVERTING THYMIDINE DIPHOSPHATE(TDP)-4-
KETO-6-DEOXY-D-GLUCOSE TO TDP-4-AMINO-4,6-DIDEOXY-D-GALACTOSE, THE
IMMEDIATE PRECURSOR OF THE ECA SUGAR TDP-FUC4NAC.
PATHWAY: INVOLVED IN THE SYNTHESIS OF ENTEROBACTERIAL COMMON
ANTIGEN (ECA) AND REQUIRED FOR SYNTHESIS OF LIPOPOLYSACCHARIDE
O-SIDE CHAINS.
|
| | wecE | b3791 | putative regulator |
EG11456 |
FUNCTION: INVOLVED IN ECA ELONGATION.
PATHWAY: INVOLVED IN THE SYNTHESIS OF ENTEROBACTERIAL COMMON
ANTIGEN (ECA) AND REQUIRED FOR SYNTHESIS OF LIPOPOLYSACCHARIDE
O-SIDE CHAINS.
SIMILARITY: BELONGS TO THE DEGT/DNRJ/ERYC1 FAMILY.
|
| | wzxE | b3792 | putative cytochrome |
EG11486 |
FUNCTION: COULD BE RFFA OR RFFC.
PATHWAY: INVOLVED IN THE SYNTHESIS OF ENTEROBACTERIAL COMMON
ANTIGEN (ECA) AND REQUIRED FOR SYNTHESIS OF LIPOPOLYSACCHARIDE
O-SIDE CHAINS.
|
| | yifM_1 | b4404 | orf, conceptual translation in SwissProt is fused with b4405 |
EG14320 |
CAUTION: THIS IS A CONCEPTUAL TRANSLATION; A FRAMESHIFT WAS
INTRODUCED IN POSITION 60 TO PRODUCE THIS ORF.
|
| 0.166577 | - | yeaR | b1797 | orf, hypothetical protein |
EG13504 |
|
| | yoaG | b1796 | orf, hypothetical protein |
EG14305 |
|
| | yeaQ | b1795 | orf, hypothetical protein |
EG13503 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
SIMILARITY: STRONG, TO E.COLI YMGE.
|
| 0.164219 | + | nupG | b2964 | transport of nucleosides, permease protein |
EG10664 |
FUNCTION: TRANSPORTS NUCLEOSIDES WITH A HIGH AFFINITY. DRIVEN BY A
PROTON MOTIVE FORCE.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE.
SIMILARITY: HIGH, TO E.COLI XAPB AND YEGT.
|
| 0.163860 | + | tolC | b3035 | outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes |
EG11009 |
FUNCTION: REQUIRED FOR PROPER EXPRESSION OF OUTER MEMBRANE PROTEIN
GENES SUCH AS OMPF, NMPC, PROTEIN 2, HEMOLYSIN, COLICIN V, OR
COLICIN E1. MAY BE SPECIALIZED FOR SIGNAL SEQUENCE INDEPENDENT,
EXTRACELLULAR SECRETION IN GRAM-NEGATIVE BACTERIA.
SUBCELLULAR LOCATION: OUTER MEMBRANE.
SIMILARITY: BELONGS TO THE PRTF FAMILY OF SECRETION PROTEINS.
CAUTION: REF.2 SEQUENCE WAS EXTENSIVELY CORRECTED BY REF.1.
|
| | ygiA | b3036 | orf, hypothetical protein |
|
|
| | ygiB | b3037 | orf, hypothetical protein |
EG11164 |
|
| | ygiC | b3038 | putative synthetase/amidase |
EG11165 |
SIMILARITY: STRONG, TO H.INFLUENZAE HI0929.
SIMILARITY: STRONG, TO THE N-TERMINAL OF E.COLI GSP AND TO E.COLI
YJFC.
|
| 0.161995 | + | gltB | b3212 | glutamate synthase, large subunit |
EG10403 |
CATALYTIC ACTIVITY: 2 L-GLUTAMATE + NADP(+) = L-GLUTAMINE +
2-OXOGLUTARATE + NADPH.
COFACTOR: BINDS A 3FE-4S CLUSTER; FAD AND FMN.
PATHWAY: NITROGEN METABOLISM, GLUTAMATE BIOSYNTHESIS.
THE CATALYZED REACTION BRINGS TOGETHER THE NITROGEN AND
CARBON METABOLISM.
SUBUNIT: AGGREGATE OF 4 CATALYTICAL ACTIVE HETERODIMERS,
CONSISTING OF A LARGE AND A SMALL SUBUNIT.
MISCELLANEOUS: GLUTAMINE BINDS TO THE LARGE SUBUNIT AND TRANSFERS
THE AMIDO GROUP TO 2-OXO-GLUTAMATE THAT APPARENTLY BINDS TO THE
SMALL SUBUNIT.
SIMILARITY: TO OTHER GLUTAMATE SYNTHASES.
|
| | gltD | b3213 | glutamate synthase, small subunit |
EG10404 |
CATALYTIC ACTIVITY: 2 L-GLUTAMATE + NADP(+) = L-GLUTAMINE +
2-OXOGLUTARATE + NADPH.
COFACTOR: BINDS A 4FE-4S CLUSTER.
PATHWAY: NITROGEN METABOLISM, GLUTAMATE BIOSYNTHESIS.
THE CATALYZED REACTION BRINGS TOGETHER THE NITROGEN AND
CARBON METABOLISM.
SUBUNIT: AGGREGATE OF 4 CATALYTICAL ACTIVE HETERODIMERS,
CONSISTING OF A LARGE AND A SMALL SUBUNIT.
MISCELLANEOUS: GLUTAMINE BINDS TO THE LARGE SUBUNIT AND TRANSFERS
THE AMIDO GROUP TO 2-OXO-GLUTAMATE THAT APPARENTLY BINDS TO THE
SMALL SUBUNIT.
SIMILARITY: THE IRON-SULFUR CENTERS ARE SIMILAR TO THOSE OF
'BACTERIAL-TYPE' 4FE-4S FERREDOXINS.
SIMILARITY: STRONG, TO E.COLI AEGA AND YGFT.
|
| 0.155954 | + | mltC | b2963 | membrane-bound lytic murein transglycosylase C |
EG12986 |
FUNCTION: MUREIN-DEGRADING ENZYME. MAY PLAY A ROLE IN RECYCLING OF
MUROPEPTIDES DURING CELL ELONGATION AND/OR CELL DIVISION (BY
SIMILARITY).
CATALYTIC ACTIVITY: CLEAVAGE OF THE BETA-1,4-GLYCOSIDIC BOND
BETWEEN N-ACETYLMURAMIC ACID AND N-ACETYLGLUCOSAMINE RESIDUES,
THEREBY CONSERVING THE ENERGY IN A NEWLY SYNTHESIZED
1,6-ANHYDROBOND IN THE MURAMIC ACID RESIDUE.
SUBCELLULAR LOCATION: ATTACHED TO THE MEMBRANE BY A LIPID
ANCHOR (PROBABLE).
SIMILARITY: STRONG, TO H.INFLUENZAE MLTC.
|
| 0.155807 | + | rfaD | b3619 | ADP-L-glycero-D-mannoheptose-6-epimerase |
EG10838 |
FUNCTION: BIOSYNTHESIS OF THE LIPOPOLYSACCHARIDE PRECURSOR ADP-L-
GLYCEROL-D-MANNOHEPTOSE.
CATALYTIC ACTIVITY: ADP-D-GLYCERO-D-MANNO-HEPTOSE = ADP-L-GLYCERO-
D-MANNO-HEPTOSE.
COFACTOR: NAD.
PATHWAY: LIPOPOLYSACCHARIDE CORE BIOSYNTHESIS.
INDUCTION: BY HEAT SHOCK.
MISCELLANEOUS: ESSENTIAL FOR ESCHERICHIA COLI VIABILITY AT
ELEVATED TEMPERATURES. INSERTIONAL INACTIVATION OF THE GENE BY THE
TN5 TRANSPOSON RESULTS IN E.COLI BEING UNABLE TO FORM COLONIES AT
TEMPERATURES ABOVE 43 DEGREES CELSIUS.
|
| | rfaF | b3620 | ADP-heptose--lps heptosyltransferase II; lipopolysaccharide core biosynthesis |
EG12210 |
PATHWAY: LIPOPOLYSACCHARIDE CORE BIOSYNTHESIS.
|
| | rfaC | b3621 | heptosyl transferase I; lipopolysaccharide core biosynthesis |
EG11189 |
FUNCTION: HEPTOSE TRANSFER TO THE LIPOPOLYSACCHARIDE CORE. IT
TRANSFERS THE INNNERMOST HEPTOSE TO [4'-P](3-DEOXY-D-MANNO-
OCTULOSONIC ACID)2-IVA.
PATHWAY: LIPOPOLYSACCHARIDE CORE BIOSYNTHESIS.
SIMILARITY: RFAQ, RFAC, AND RFAF MAY BELONG TO A COMMON FAMILY OF
TRANSFERASES INVOLVED IN SYNTHESIS OF THE INNER CORE REGION.
|
| | rfaL | b3622 | O-antigen ligase; lipopolysaccharide core biosynthesis |
EG11424 |
FUNCTION: ADDS THE O-ANTIGEN ON THE GLUCOSE GROUP OF LPS.
PATHWAY: LIPOPOLYSACCHARIDE CORE BIOSYNTHESIS.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN.
SIMILARITY: SHOWS ALMOST NO SIMILARITY TO S.TYPHIMURIUM RFAL.
|
| 0.155484 | - | udhA | b3962 | putative oxidoreductase |
EG11428 |
FUNCTION: CONVERSION OF NADPH, GENERATED BY PERIPHERAL CATABOLIC
PATHWAYS, TO NADH, WHICH CAN ENTER THE RESPIRATORY CHAIN FOR
ENERGY GENERATION.
CATALYTIC ACTIVITY: NADPH + NAD(+) = NADP(+) + NADH.
COFACTOR: FAD.
SUBUNIT: HOMOOLIGOMER; PROBABLE HOMOOCTAMER.
SUBCELLULAR LOCATION: CYTOPLASMIC.
SIMILARITY: BELONGS TO THE PYRIDINE NUCLEOTIDE-DISULFIDE
OXIDOREDUCTASES CLASS-I.
CAUTION: REF.4 SEQUENCE DIFFERS FROM THAT SHOWN DUE TO A
FRAMESHIFT IN POSITION 14.
|
| 0.144409 | + | ydhE | b1663 | putative transport protein |
EG12400 |
FUNCTION: FUNCTIONS AS A NA(+)/DRUG ANTIPORTER (BY SIMILARITY).
CONFERS RESISTANCE TO SEVERAL DRUGS, SUCH AS NORFLOXACIN,
CIPROFLOXACIN, ACRIFLAVINE AND THE TETRAPHENYLPHOSPHONIUM ION.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE
(POTENTIAL).
SIMILARITY: BELONGS TO THE MULTI ANTIMICROBIAL EXTRUSION (MATE)
FAMILY. NORM (TC 2.A.66.1.1) SUBFAMILY.
|
| 0.137742 | + | dnaB | b4052 | replicative DNA helicase; part of primosome |
EG10236 |
FUNCTION: PARTICIPATES IN INITIATION AND ELONGATION DURING
CHROMOSOME REPLICATION; IT EXHIBITS DNA-DEPENDENT ATPASE ACTIVITY
AND CONTAINS DISTINCT ACTIVE SITES FOR ATP BINDING, DNA BINDING,
AND INTERACTION WITH DNAC PROTEIN, PRIMASE, AND OTHER PREPRIMING
PROTEINS.
SUBUNIT: HOMOHEXAMER.
SIMILARITY: BELONGS TO THE DNAB SUBFAMILY OF HELICASES.
|
| | alr | b4053 | alanine racemase 1 |
EG10001 |
FUNCTION: CELL WALL FORMATION.
CATALYTIC ACTIVITY: L-ALANINE = D-ALANINE.
COFACTOR: PYRIDOXAL PHOSPHATE.
PATHWAY: ALONG WITH D-ALANINE-D-ALANINE LIGASE, IT MAKES UP THE
D-ALANINE BRANCH OF THE PEPTIDOGLYCAN BIOSYNTHETIC ROUTE.
SUBUNIT: MONOMER.
SIMILARITY: BELONGS TO THE ALANINE RACEMASE FAMILY.
|
| 0.137190 | + | dld | b2133 | D-lactate dehydrogenase, FAD protein, NADH independent |
EG10231 |
FUNCTION: FIRST COMPONENT OF THE MEMBRANE-BOUND D-LACTATE OXIDASE,
WHICH IS BELIEVED TO PLAY AN IMPORTANT ROLE IN THE ENERGIZATION OF
THE ACTIVE TRANSPORT OF A VARIETY OF SUGARS AND AMINO ACIDS.
CATALYTIC ACTIVITY: D-LACTATE + NAD(+) = PYRUVATE + NADH.
COFACTOR: FAD.
ENZYME REGULATION: REQUIRES PHOSPHOLIPID FOR MAXIMAL ACTIVITY.
SUBCELLULAR LOCATION: MEMBRANE BOUND LOCATED AT THE INNER FACE OF
THE CYTOPLASMIC MEMBRANE.
|
| 0.136376 | - | yhfG | b3362 | orf, hypothetical protein |
EG12374 |
|
| | fic | b3361 | induced in stationary phase, recognized by rpoS, affects cell division |
EG10307 |
FUNCTION: INVOLVED IN CELL FILAMENTATION INDUCED BY CYCLIC AMP.
MAY HAVE SOME ROLE IN CELL DIVISION.
|
| | pabA | b3360 | p-aminobenzoate synthetase, component II |
EG10682 |
FUNCTION: CATALYZES THE BIOSYNTHESIS OF 4-AMINO-4-DEOXYCHORISMATE
(ADC) FROM CHORISMATE AND GLUTAMINE.
PATHWAY: FOLATE BIOSYNTHESIS PATHWAY. FIRST STEP IN THE
BIOSYNTHESIS OF P-AMINOBENZOATE (PABA).
SUBUNIT: CONSISTS OF TWO NONIDENTICAL CHAINS: COMPONENT I
CATALYZES THE FORMATION OF ADC BY BINDING CHORISMATE AND AMMONIA;
COMPONENT II PROVIDES THE GLUTAMINE AMIDOTRANSFERASE ACTIVITY.
SIMILARITY: TO OTHER TYPE-1 GLUTAMINE AMIDOTRANSFERASE DOMAINS.
|
| | argD | b3359 | acetylornithine delta-aminotransferase |
EG10066 |
CATALYTIC ACTIVITY: N2-ACETYL-L-ORNITHINE + 2-OXOGLUTARATE =
N-ACETYL-L-GLUTAMATE 5-SEMIALDEHYDE + L-GLUTAMATE.
COFACTOR: PYRIDOXAL PHOSPHATE.
PATHWAY: FOURTH STEP IN ARGININE BIOSYNTHESIS.
MISCELLANEOUS: THE REACTION CATALYZED BY ACOAT IS HIGHLY
REVERSIBLE. MOREOVER THIS ENZYME MAY TRANSAMINATE ORNITHINE.
SIMILARITY: BELONGS TO CLASS-III OF PYRIDOXAL-PHOSPHATE-DEPENDENT
AMINOTRANSFERASES.
|
| 0.133874 | + | cof | b0446 | orf, hypothetical protein |
EG13216 |
SIMILARITY: BELONGS TO THE COF/YBHA/YIDA/YIGL (E.COLI) / YCSE/YXEH
(B.SUBTILIS) FAMILY.
|
| | ybaO | b0447 | putative LRP-like transcriptional regulator |
EG13218 |
SIMILARITY: BELONGS TO THE ASNC FAMILY OF TRANSCRIPTIONAL
REGULATORS.
|
| | mdlA | b0448 | ATP-binding component of a transport system |
EG11622 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE
(POTENTIAL).
SIMILARITY: BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY
(ABC TRANSPORTERS). MDR SUBFAMILY.
CAUTION: REF.1 SEQUENCE DIFFERS FROM THAT SHOWN DUE TO A
FRAMESHIFT THAT FUSES MDLA AND MDLB.
|
| | mdlB | b0449 | putative ATP-binding component of a transport system |
EG14374 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE
(POTENTIAL).
SIMILARITY: BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY
(ABC TRANSPORTERS). MDR SUBFAMILY.
CAUTION: REF.1 SEQUENCE DIFFERS FROM THAT SHOWN DUE TO A
FRAMESHIFT THAT FUSES MDLA AND MDLB.
|
| 0.124644 | + | fliO | b1947 | flagellar biosynthesis |
EG11224 |
SUBCELLULAR LOCATION: MEMBRANE-ASSOCIATED (POTENTIAL).
SIMILARITY: BELONGS TO THE FLIO/MOPB FAMILY.
|
| | fliP | b1948 | flagellar biosynthesis |
EG11975 |
FUNCTION: PLAYS A ROLE IN THE FLAGELLUM-SPECIFIC TRANSPORT SYSTEM.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN.
SIMILARITY: BELONGS TO THE FLIP/MOPC/SPAP FAMILY.
|
| | fliQ | b1949 | flagellar biosynthesis |
EG11976 |
FUNCTION: REQUIRED FOR THE ASSEMBLY OF THE RIVET AT THE EARLIEST
STAGE OF FLAGELLAR BIOSYNTHESIS.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN.
SIMILARITY: BELONGS TO THE FLIQ/MOPD/SPAQ FAMILY.
|
| | fliR | b1950 | flagellar biosynthesis |
EG11977 |
FUNCTION: ROLE IN FLAGELLAR BIOSYNTHESIS.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN.
SIMILARITY: BELONGS TO THE FLIR/MOPE/SPAR FAMILY.
|
| 0.118497 | + | yjeR | b4162 | orf, hypothetical protein |
EG12480 |
FUNCTION: 3'-TO-5' EXORIBONUCLEASE SPECIFIC FOR SMALL
OLIGORIBONUCLEOTIDES.
SUBUNIT: HOMODIMER.
SUBCELLULAR LOCATION: CYTOPLASMIC (POTENTIAL).
SIMILARITY: BELONGS TO THE OLIGORIBONUCLEASE FAMILY.
|
| 0.117267 | - | tpiA | b3919 | triosephosphate isomerase |
EG11015 |
CATALYTIC ACTIVITY: D-GLYCERALDEHYDE 3-PHOSPHATE = DIHYDROXY-
ACETONE PHOSPHATE.
PATHWAY: PLAYS AN IMPORTANT ROLE IN SEVERAL METABOLIC PATHWAYS.
SUBUNIT: HOMODIMER.
SIMILARITY: BELONGS TO THE TRIOSEPHOSPHATE ISOMERASE FAMILY.
|
| 0.115883 | + | yieE | b3712 | orf, hypothetical protein |
EG11722 |
|
| | yieF | b3713 | orf, hypothetical protein |
EG11723 |
SIMILARITY: BELONGS TO THE SSUE FAMILY.
|
| 0.115550 | + | yhiR | b3499 | orf, hypothetical protein |
EG12234 |
SIMILARITY: STRONG, TO H.INFLUENZAE HI0441.
|
| | gor | b3500 | glutathione oxidoreductase |
EG10412 |
FUNCTION: MAINTAIN HIGH LEVELS OF REDUCED GLUTATHIONE IN THE
CYTOSOL.
CATALYTIC ACTIVITY: NADPH + OXIDIZED GLUTATHIONE = NADP(+) +
2 GLUTATHIONE.
COFACTOR: FAD.
SUBUNIT: HOMODIMER.
SUBCELLULAR LOCATION: CYTOPLASMIC.
MISCELLANEOUS: THE ACTIVE SITE IS A REDOX-ACTIVE DISULFIDE BOND.
SIMILARITY: BELONGS TO THE PYRIDINE NUCLEOTIDE-DISULFIDE
OXIDOREDUCTASES CLASS-I.
|
| 0.115506 | - | yhhM | b3467 | putative receptor |
EG12213 |
|