Score |
Strand | Gene name |
Blattner ID |
Description |
EcoCyc link |
SwissProt comment |
| 2.646965 | + | ybcW | b0559 | orf, hypothetical protein |
EG13639 |
 |
| 2.108659 | + | yicP | b3665 | probable adenine deaminase (synthesis xanthine) |
EG11692 |
CATALYTIC ACTIVITY: ADENINE + H(2)O = HYPOXANTHINE + NH(3).
SIMILARITY: BELONGS TO THE ADENINE AMINASE FAMILY.
|
| 1.659830 | + | mdoG | b1048 | periplasmic glucans biosynthesis protein |
EG11885 |
FUNCTION: INVOLVED IN THE BIOSYNTHESIS OF PERIPLASMIC MEMBRANE-
DERIVED OLIGOSACCHARIDES (MDO).
PATHWAY: OPG (OSMOREGULATED PERIPLASMIC GLUCANS) BIOSYNTHESIS.
SUBCELLULAR LOCATION: PERIPLASMIC.
SIMILARITY: TO P.SYRINGAE HYPOTHETICAL 40 KDA PROTEIN IN HRP LOCUS
(AC P20400) AND TO E.COLI YDCG.
|
| | mdoH | b1049 | membrane glycosyltransferase; synthesis of membrane-derived oligosaccharide (MDO) |
EG11886 |
FUNCTION: NECESSARY FOR NORMAL GLUCOSYLTRANSFERASE ACTIVITY. IT
COULD BE A GLUCOSYL TRANSFERASE OR SIMPLY A SUBUNIT OF THIS
ENZYME.
PATHWAY: OPG (OSMOREGULATED PERIPLASMIC GLUCANS) BIOSYNTHESIS.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE.
SIMILARITY: BELONGS TO THE GLYCOSYLTRANSFERASE FAMILY 2. STRONG,
TO P.SYRINGAE HRPM.
|
| 1.633529 | + | nhaA | b0019 | Na+/H antiporter, pH dependent |
EG10652 |
FUNCTION: THIS IS A NA+/H+ ANTIPORTER. IT CAN MEDIATE SODIUM
UPTAKE WHEN A TRANSMEMBRANE PH GRADIENT IS APPLIED. IT PROBABLY
ACTS IN THE REGULATION OF INTERNAL PH AT THE ALKALINE PH RANGE. IT
CATALYZES THE EXCHANGE OF 2H+ PER NA+. ITS ACTIVITY IS HIGHLY
DEPENDENT ON THE PH.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE.
INDUCTION: TRANSCRIPTION STIMULATED BY HIGH NA+ CONCENTRATIONS.
|
| | nhaR | b0020 | transcriptional activator of nhaA |
EG11078 |
FUNCTION: PLAYS A ROLE IN THE POSITIVE REGULATION OF NHAA.
SUBCELLULAR LOCATION: CYTOPLASMIC.
SIMILARITY: BELONGS TO THE LYSR FAMILY OF TRANSCRIPTIONAL
REGULATORS.
|
| 1.398888 | + | frwC | b3949 | PTS system, fructose-like enzyme II component |
EG11908 |
FUNCTION: THIS IS A COMPONENT OF THE PHOSPHOENOLPYRUVATE-DEPENDENT
SUGAR PHOSPHOTRANSFERASE SYSTEM (PTS), A MAJOR CARBOHYDRATE ACTIVE
-TRANSPORT SYSTEM. THE IICD DOMAINS CONTAIN THE SUGAR BINDING SITE
AND THE TRANSMEMBRANE CHANNEL; THE IIA DOMAIN CONTAINS THE PRIMARY
PHOSPHORYLATION SITE (THE DONOR IS PHOSPHO-HPR); IIA TRANSFERS ITS
PHOSPHORYL GROUP TO THE IIB DOMAIN WHICH FINALLY TRANSFERS IT TO
THE SUGAR.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
SIMILARITY: CONTAINS A PTS EIIC DOMAIN.
|
| | frwB | b3950 | PTS system fructose-like IIB component 1 |
EG11909 |
FUNCTION: THIS IS A COMPONENT OF THE PHOSPHOENOLPYRUVATE-DEPENDENT
SUGAR PHOSPHOTRANSFERASE SYSTEM (PTS), A MAJOR CARBOHYDRATE ACTIVE
-TRANSPORT SYSTEM. THE IICD DOMAINS CONTAIN THE SUGAR BINDING SITE
AND THE TRANSMEMBRANE CHANNEL; THE IIA DOMAIN CONTAINS THE PRIMARY
PHOSPHORYLATION SITE (THE DONOR IS PHOSPHO-HPR); IIA TRANSFERS ITS
PHOSPHORYL GROUP TO THE IIB DOMAIN WHICH FINALLY TRANSFERS IT TO
THE SUGAR.
CATALYTIC ACTIVITY: PROTEIN N-PHOSPHOHISTIDINE + SUGAR =
PROTEIN HISTIDINE + SUGAR PHOSPHATE.
SUBCELLULAR LOCATION: CYTOPLASMIC.
SIMILARITY: CONTAINS A PTS EIIB DOMAIN.
|
| | pflD | b3951 | formate acetyltransferase 2 |
EG11910 |
CATALYTIC ACTIVITY: ACETYL-COA + FORMATE = COA + PYRUVATE.
PATHWAY: GLUCOSE METABOLISM (NONOXIDATIVE CONVERSION).
SUBCELLULAR LOCATION: CYTOPLASMIC (BY SIMILARITY).
SIMILARITY: STRONG, TO OTHER PYRUVATE FORMATE-LYASES.
|
| | pflC | b3952 | probable pyruvate formate lyase activating enzyme 2 |
EG11911 |
FUNCTION: ACTIVATION OF PYRUVATE FORMATE-LYASE 2 UNDER ANAEROBIC
CONDITIONS BY GENERATION OF AN ORGANIC FREE RADICAL, USING
S-ADENOSYLMETHIONINE AND REDUCED FLAVODOXIN AS COSUBSTRATES TO
PRODUCE 5'-DEOXY-ADENOSINE (BY SIMILARITY).
CATALYTIC ACTIVITY: S-ADENOSYL-L-METHIONINE + DIHYDROFLAVODOXIN +
[PYRUVATE FORMATE-LYASE]- GLYCINE = 5'-DEOXYADENOSINE + METHIONINE
+ FLAVODOXIN + [PYRUVATE FORMATE-LYASE]-GLYCINE RADICAL.
COFACTOR: BINDS A 4FE-4S CLUSTER (BY SIMILARITY).
SUBCELLULAR LOCATION: CYTOPLASMIC (BY SIMILARITY).
SIMILARITY: BELONGS TO THE ORGANIC RADICAL ACTIVATING ENZYMES
FAMILY.
|
| | frwD | b3953 | PTS system fructose-like IIB component 2 |
EG11912 |
FUNCTION: THIS IS A COMPONENT OF THE PHOSPHOENOLPYRUVATE-DEPENDENT
SUGAR PHOSPHOTRANSFERASE SYSTEM (PTS), A MAJOR CARBOHYDRATE ACTIVE
-TRANSPORT SYSTEM. THE IICD DOMAINS CONTAIN THE SUGAR BINDING SITE
AND THE TRANSMEMBRANE CHANNEL; THE IIA DOMAIN CONTAINS THE PRIMARY
PHOSPHORYLATION SITE (THE DONOR IS PHOSPHO-HPR); IIA TRANSFERS ITS
PHOSPHORYL GROUP TO THE IIB DOMAIN WHICH FINALLY TRANSFERS IT TO
THE SUGAR.
CATALYTIC ACTIVITY: PROTEIN N-PHOSPHOHISTIDINE + SUGAR =
PROTEIN HISTIDINE + SUGAR PHOSPHATE.
SUBCELLULAR LOCATION: CYTOPLASMIC.
SIMILARITY: CONTAINS A PTS EIIB DOMAIN.
|
| 1.084616 | + | b2080 | b2080 | orf, hypothetical protein |
EG14059 |
SIMILARITY: STRONG, TO ORTHOLOG IN P.STUTZERI.
|
| | yegQ | b2081 | orf, hypothetical protein |
EG14060 |
SIMILARITY: BELONGS TO PEPTIDASE FAMILY U32.
SIMILARITY: STRONG, TO H.INFLUENZAE HI0419.
|
| 1.059430 | + | fadL | b2344 | transport of long-chain fatty acids; sensitivity to phage T2 |
EG10280 |
FUNCTION: INVOLVED IN TRANSLOCATION OF LONG-CHAIN FATTY ACIDS
ACROSS THE OUTER MEMBRANE. IT IS A RECEPTOR FOR THE BACTERIOPHAGE
T2. FADL MAY FORM A SPECIFIC CHANNEL.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. OUTER MEMBRANE.
CONTAINS SEVERAL POTENTIAL TRANSMEMBRANE DOMAINS.
INDUCTION: BY LONG-CHAIN FATTY ACIDS. EXPRESSION OF FADL IS UNDER
THE CONTROL OF THE FADR REPRESSOR.
SIMILARITY: STRONG, TO H.INFLUENZAE OUTER MEMBRANE PROTEIN P1.
|
| 1.049664 | + | hmpA | b2552 | dihydropteridine reductase, ferrisiderophore reductase activity |
EG10456 |
FUNCTION: POSSESSES DIHYDROPTERIDINE REDUCTASE ACTIVITY. ALSO HAS
NITRIC OXIDE DIOXYGENASE ACTIVITY.
FUNCTION: SEEMS TO REDUCES THE COMPLEXED FE+3 IRON OF SIDEROPHORES
TO FE+2, THUS RELEASING IT FROM THE CHELATOR.
CATALYTIC ACTIVITY: NAD(P)H + 6,7-DIHYDROPTERIDINE = NAD(P)(+) +
5,6,7,8-TETRAHYDROPTERIDINE.
SUBUNIT: MONOMER.
DOMAIN: CONSISTS OF TWO DISTINCT DOMAINS; ONE IS A HEME-CONTAINING
OXYGEN BINDING DOMAIN IN THE N-TERMINAL REGION AND THE OTHER IS AN
FAD-CONTAINING REDUCTASE DOMAIN FOUND IN THE C-TERMINAL REGION.
SIMILARITY: BELONGS TO THE GLOBIN FAMILY. TWO DOMAINS
FLAVOHEMOPROTEINS SUBFAMILY.
SIMILARITY: TO A NUMBER OF FAD/NAD(P) FLAVOPROTEIN
OXIDOREDUCTASES.
|
| 0.994763 | + | b2880 | b2880 | orf, hypothetical protein |
EG13063 |
|
| | b2881 | b2881 | putative dehydrogenase |
|
|
| | ygfO | b2882 | putative transport protein |
EG13065 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (PROBABLE).
SIMILARITY: BELONGS TO THE XANTHINE/URACIL PERMEASES FAMILY.
|
| | ygfP | b2883 | orf, hypothetical protein |
EG13066 |
FUNCTION: CATALYZES THE HYDROLYTIC DEAMINATION OF GUANINE,
PRODUCING XANTHINE AND AMMONIA.
CATALYTIC ACTIVITY: GUANINE + H(2)O = XANTHINE + NH(3).
COFACTOR: CONTAINS 1 MOLE OF ZINC PER SUBUNIT.
PATHWAY: PURINE NUCLEOTIDE CATABOLISM.
SIMILARITY: BELONGS TO THE ATZ/TRZ FAMILY.
|
| | ygfQ | b2884 | orf, hypothetical protein |
EG13067 |
SIMILARITY: BELONGS TO THE YICO/YIEG/YJCD FAMILY. CORRESPONDS TO
THE N-TERMINAL PART; THE C-TERMINAL PART IS YGFR.
|
| | ygfR | b2885 | putative oxidoreductase |
EG13068 |
SIMILARITY: BELONGS TO THE YICO/YIEG/YJCD FAMILY. CORRESPONDS TO
THE C-TERMINAL PART; THE N-TERMINAL PART IS YGFQ.
|
| 0.927440 | - | purC | b2476 | phosphoribosylaminoimidazole-succinocarboxamide synthetase = SAICAR synthetase |
EG10791 |
CATALYTIC ACTIVITY: ATP + 1-(5-PHOSPHORIBOSYL)-4-CARBOXY-5-
AMINOIMIDAZOLE + L-ASPARTATE = ADP + ORTHOPHOSPHATE + 1-(5-
PHOSPHORIBOSYL)-4-(N-SUCCINO-CARBOXAMIDE)-5-AMINOIMIDAZOLE.
PATHWAY: SEVENTH STEP IN DE NOVO PURINE BIOSYNTHESIS.
SUBUNIT: HOMOTRIMER.
SIMILARITY: BELONGS TO THE SAICAR SYNTHETASE FAMILY.
|
| 0.910701 | + | yjgK | b4252 | orf, hypothetical protein |
EG12530 |
SIMILARITY: BELONGS TO THE YHCH/YIAL/YJGK FAMILY.
|
| | yjgL | b4253 | orf, hypothetical protein |
EG12531 |
|
| 0.879328 | + | yigL | b3826 | orf, hypothetical protein |
EG11470 |
SIMILARITY: BELONGS TO THE COF/YBHA/YIDA/YIGL (E.COLI) / YCSE/YXEH
(B.SUBTILIS) FAMILY. STRONG, TO H.INFLUENZAE HI0597.
CAUTION: THIS IS A CONCEPTUAL TRANSLATION; REF.1 SEQUENCE DIFFERS
FROM THAT SHOWN DUE TO FRAMESHIFTS.
|
| 0.873052 | + | yqhG | b3013 | orf, hypothetical protein |
EG13017 |
|
| | yqhH | b3014 | orf, hypothetical protein |
EG13018 |
SUBCELLULAR LOCATION: ATTACHED TO THE OUTER MEMBRANE BY A LIPID
ANCHOR (BY SIMILARITY).
SIMILARITY: TO MAJOR OUTER MEMBRANE LIPOPROTEIN (LPP).
|
| 0.694288 | + | b1458 | b1458 | orf, hypothetical protein |
|
|
| | b1459 | b1459 | orf, hypothetical protein |
|
|
| 0.662596 | + | yejA | b2177 | orf, hypothetical protein |
EG12037 |
SIMILARITY: SOME, TO H.INFLUENZAE HBPA.
|
| | yejB | b2178 | putative transport system permease protein |
EG12038 |
FUNCTION: PROBABLY PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT
SYSTEM. PROBABLY RESPONSIBLE FOR THE TRANSLOCATION OF THE
SUBSTRATE ACROSS THE MEMBRANE.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE
(POTENTIAL).
SIMILARITY: WITH INTEGRAL MEMBRANE COMPONENTS OF OTHER BINDING-
PROTEIN-DEPENDENT TRANSPORT SYSTEMS. BELONGS TO THE OPPBC
SUBFAMILY.
CAUTION: REF.1 SEQUENCE DIFFERS FROM THAT SHOWN DUE TO A
FRAMESHIFT IN POSITION 126.
|
| | yejE | b2179 | putative transport system permease protein |
EG12040 |
FUNCTION: PROBABLY PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT
SYSTEM. PROBABLY RESPONSIBLE FOR THE TRANSLOCATION OF THE
SUBSTRATE ACROSS THE MEMBRANE.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE
(POTENTIAL).
SIMILARITY: WITH INTEGRAL MEMBRANE COMPONENTS OF OTHER BINDING-
PROTEIN-DEPENDENT TRANSPORT SYSTEMS. BELONGS TO THE OPPBC
SUBFAMILY.
|
| | yejF | b2180 | putative ATP-binding component of a transport system |
EG12041 |
SIMILARITY: BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY
(ABC TRANSPORTERS).
|
| 0.618915 | + | gapA | b1779 | glyceraldehyde-3-phosphate dehydrogenase A |
EG10367 |
CATALYTIC ACTIVITY: D-GLYCERALDEHYDE 3-PHOSPHATE + ORTHOPHOSPHATE
+ NAD(+) = 1,3-DIPHOSPHATEGLYCERATE + NADH.
PATHWAY: FIRST STEP IN THE SECOND PHASE OF GLYCOLYSIS.
SUBUNIT: HOMOTETRAMER.
SUBCELLULAR LOCATION: CYTOPLASMIC.
SIMILARITY: BELONGS TO THE GLYCERALDEHYDE 3-PHOSPHATE
DEHYDROGENASE FAMILY.
|
| | yeaD | b1780 | orf, hypothetical protein |
EG12679 |
SIMILARITY: BELONGS TO THE UPF0010 FAMILY. SIGNIFICANTLY RELATED
TO MUTAROTASE.
|
| 0.607524 | + | pepN | b0932 | aminopeptidase N |
EG10696 |
FUNCTION: AMINOPEPTIDASE N IS INVOLVED IN THE DEGRADATION OF
INTRACELLULAR PEPTIDES GENERATED BY PROTEIN BREAKDOWN DURING
NORMAL GROWTH AS WELL AS IN RESPONSE TO NUTRIENT STARVATION.
COFACTOR: BINDS ONE ZINC ION.
SUBCELLULAR LOCATION: CYTOPLASMIC, BOUND TO THE INNER FACE OF
THE CYTOPLASMIC MEMBRANE.
SIMILARITY: BELONGS TO PEPTIDASE FAMILY M1 (ZINC METALLOPROTEASE);
ALSO KNOWN AS THE PEPN SUBFAMILY.
|
| 0.570401 | - | b2817 | b2817 | putative amidase |
EG13086 |
FUNCTION: CELL-WALL HYDROLASE PROBABLY INVOLVED IN CELL-WALL
HYDROLYSIS, SEPTATION OR RECYCLING (BY SIMILARITY).
CATALYTIC ACTIVITY: HYDROLYZES THE LINK BETWEEN N-ACETYLMURAMOYL
RESIDUES AND L-AMINO ACID RESIDUES IN CERTAIN BACTERIAL CELL-WALL
GLYCOPEPTIDES.
SIMILARITY: BELONGS TO THE N-ACETYLMURAMOYL-L-ALANINE AMIDASE
FAMILY 3.
|
| 0.554028 | - | nlpD | b2742 | lipoprotein |
EG12111 |
FUNCTION: MAY BE INVOLVED IN STATIONARY-PHASE SURVIVAL.
SUBCELLULAR LOCATION: ATTACHED TO THE INNER MEMBRANE BY A LIPID
ANCHOR (POTENTIAL).
SIMILARITY: BELONGS TO THE E.COLI NLPD / HAEMOPHILUS LPPB FAMILY.
|
| | rpoS | b2741 | RNA polymerase, sigma S (sigma38) factor; synthesis of many growth phase related proteins |
EG10510 |
FUNCTION: SIGMA TRANSCRIPTION FACTOR CONTROLLING A REGULON OF
GENES REQUIRED FOR PROTECTION AGAINST EXTERNAL STRESSES. POSSIBLY,
IT AFFECTS THE EXPRESSION OF KATE (CATALASE HPII), XTHA
(ENDONUCLEASE III), THE APPABC OPERON AND OTHER GENES BY MODIFYING
THE AFFINITY OF RNA POLYMERASE FOR THE PROMOTERS.
SIMILARITY: BELONGS TO THE SIGMA-70 FACTOR FAMILY.
|
| 0.494930 | - | yecK | b1873 | putative cytochrome C-type protein |
EG13277 |
FUNCTION: PART OF THE RESPIRATORY CHAIN OF BISZ (PROBABLE).
SUBCELLULAR LOCATION: TYPE II MEMBRANE PROTEIN. INNER MEMBRANE
(POTENTIAL).
PTM: BINDS FIVE HEME GROUPS PER MOLECULE (BY SIMILARITY).
SIMILARITY: STRONG, TO E.COLI TORC.
|
| | bisZ | b1872 | biotin sulfoxide reductase 2 |
EG13276 |
FUNCTION: THIS ENZYME MAY SERVE AS A SCAVENGER, ALLOWING THE CELL
TO UTILIZE BIOTIN SULFOXIDE AS A BIOTIN SOURCE (BY SIMILARITY).
CATALYTIC ACTIVITY: REDUCES A SPONTANEOUS OXIDATION PRODUCT OF
BIOTIN, D-BIOTIN D-SULFOXIDE (BSO OR BDS), BACK TO BIOTIN.
COFACTOR: MOLYBDENUM (MOLYBDOPTERIN) (BY SIMILARITY).
SIMILARITY: BELONGS TO THE PROKARYOTIC MOLYBDOPTERIN-CONTAINING
OXIDOREDUCTASE FAMILY.
|
| 0.494047 | + | greB | b3406 | transcription elongation factor and transcript cleavage |
EG11578 |
FUNCTION: NECESSARY FOR EFFICIENT RNA POLYMERASE TRANSCRIPTION
ELONGATION PAST TEMPLATE-ENCODED ARRESTING SITES. THE ARRESTING
SITES IN DNA HAVE THE PROPERTY OF TRAPPING A CERTAIN FRACTION
OF ELONGATING RNA POLYMERASES THAT PASS THROUGH, RESULTING IN
LOCKED TERNARY COMPLEXES. CLEAVAGE OF THE NASCENT TRANSCRIPT BY
CLEAVAGE FACTORS SUCH AS GREA OR GREB ALLOWS THE RESUMPTION OF
ELONGATION FROM THE NEW 3'TERMINUS. GREB RELEASES SEQUENCES OF
UP TO 9 NUCLEOTIDES IN LENGTH.
SIMILARITY: BELONGS TO THE GREA/GREB FAMILY.
|
| 0.475838 | + | yehL | b2119 | orf, hypothetical protein |
EG11998 |
|
| | yehM | b2120 | orf, hypothetical protein |
EG11999 |
CAUTION: REF.1 SEQUENCE DIFFERS FROM THAT SHOWN DUE TO FRAMESHIFTS
IN POSITIONS 283 AND 403 THAT PRODUCE THREE SEPARATE ORFS.
|
| | yehP | b2121 | orf, hypothetical protein |
EG12002 |
|
| | yehQ | b2122 | orf, hypothetical protein |
EG12003 |
|
| 0.453717 | - | argT | b2310 | lysine-, arginine-, ornithine-binding periplasmic protein |
EG10072 |
FUNCTION: THIS PERIPLASMIC BINDING PROTEIN IS INVOLVED IN AN
ARGININE TRANSPORT SYSTEM. ARGT AND HISTIDINE-BINDING PROTEIN J
(HISJ) INTERACT WITH A COMMON MEMBRANE-BOUND RECEPTOR, HISP.
SUBCELLULAR LOCATION: PERIPLASMIC.
PTM: PHOSHORYLATED BY ARGK.
SIMILARITY: BELONGS TO THE BACTERIAL EXTRACELLULAR SOLUTE-BINDING
PROTEIN FAMILY 3.
|
| 0.439354 | + | ubiC | b4039 | chorismate lyase |
EG11369 |
CATALYTIC ACTIVITY: CHORISMATE = 4-HYDROXYBENZOATE + PYRUVATE.
PATHWAY: FIRST STEP IN UBIQUINONE BIOSYNTHESIS.
SUBUNIT: MONOMER.
SUBCELLULAR LOCATION: CYTOPLASMIC.
|
| | ubiA | b4040 | 4-hydroxybenzoate-octaprenyltransferase |
EG11370 |
FUNCTION: SYNTHESIS OF 3-OCTAPRENYL-4-HYDROXYBENZOATE.
CATALYTIC ACTIVITY: 4-HYDROXYBENZOATE + FARNESYLFARNESYLGERANIOL
= 3-OCTAPRENYL-4-HYDROXYBENZOATE.
COFACTOR: REQUIRES MAGNESIUM.
PATHWAY: SECOND STEP IN UBIQUINONE BIOSYNTHESIS.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE.
SIMILARITY: BELONGS TO THE UBIA PRENYLTRANSFERASE FAMILY.
|
| 0.423082 | + | b1627 | b1627 | orf, hypothetical protein |
|
|
| | b1628 | b1628 | orf, hypothetical protein |
EG13934 |
SIMILARITY: BELONGS TO THE 4FE4S BACTERIAL-TYPE FERREDOXIN FAMILY.
STRONG, TO H.INFLUENZAE HI1684.
|
| | b1629 | b1629 | putative membrane protein |
|
|
| | ydgO | b1630 | orf, hypothetical protein |
EG13936 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
SIMILARITY: BELONGS TO THE RNFD FAMILY. STRONG, TO H.INFLUENZAE
HI1686.
|
| | b1631 | b1631 | orf, hypothetical protein |
EG13937 |
SIMILARITY: BELONGS TO THE RNFG FAMILY. STRONG, TO H.INFLUENZAE
HI1687.
|
| | ydgQ | b1632 | orf, hypothetical protein |
EG13938 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
SIMILARITY: STRONG, TO H.INFLUENZAE HI1688.
SIMILARITY: TO H.INFLUENZAE HI0168.
|
| | nth | b1633 | endonuclease III; specific for apurinic and/or apyrimidinic sites |
EG10662 |
FUNCTION: HAS BOTH AN APURINIC AND/OR APYRIMIDINIC ENDONUCLEASE
ACTIVITY AND A DNA N-GLYCOSYLASE ACTIVITY. INCISES DAMAGED DNA AT
CYTOSINES, THYMINES AND GUANINES. ACTS ON A DAMAGED STRAND, 5'
FROM THE DAMAGED SITE. REQUIRED FOR THE REPAIR OF BOTH OXIDATIVE
DNA DAMAGE AND SPONTANEOUS MUTAGENIC LESIONS.
CATALYTIC ACTIVITY: ENDONUCLEOLYTIC CLEAVAGE NEAR APURINIC OR
APYRIMIDINIC SITES TO PRODUCTS WITH 5'-PHOSPHATE.
COFACTOR: BINDS A 4FE-4S CLUSTER WHICH IS NOT IMPORTANT FOR THE
CATALYTIC ACTIVITY, BUT WHICH IS PROBABLY INVOLVED IN THE PROPER
POSITIONING OF THE ENZYME ALONG THE DNA STRAND.
SUBUNIT: MONOMER.
SIMILARITY: BELONGS TO THE NTH/MUTY FAMILY.
|
| 0.412339 | + | mdaB | b3028 | modulator of drug activity B |
EG12656 |
SIMILARITY: TO H.INFLUENZAE HI0648 AND S.POMBE SPAC5H10.05C.
|
| | ygiN | b3029 | orf, hypothetical protein |
EG12657 |
|
| 0.410804 | + | ynfM | b1596 | putative transport protein |
EG12951 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE
(POTENTIAL).
SIMILARITY: BELONGS TO THE MAJOR FACILITATOR FAMILY (ALSO KNOWN
AS THE DRUG RESISTANCE TRANSLOCASE FAMILY).
|
| 0.401731 | + | b2446 | b2446 | orf, hypothetical protein |
EG14176 |
|
| | b2447 | b2447 | orf, hypothetical protein |
EG14177 |
|
| 0.396472 | + | mcrA | b1159 | restriction of DNA at 5-methylcytosine residues; at locus of e14 element |
EG10573 |
FUNCTION: RESTRICTION OF 5-METHYL AND 5-HYDROXYMETHYLCYTOSINES AT
THE SPECIFIC DNA SEQUENCE C(ME)CGG.
|
| 0.384081 | + | glpA | b2241 | sn-glycerol-3-phosphate dehydrogenase (anaerobic), large subunit |
EG10391 |
FUNCTION: CONVERSION OF GLYCEROL 3-PHOSPHATE TO DIHYDROXYACETONE.
USES FUMARATE OR NITRATE AS ELECTRON ACCEPTOR.
CATALYTIC ACTIVITY: SN-GLYCEROL 3-PHOSPHATE + ACCEPTOR =
GLYCERONEPHOSPHATE + REDUCED ACCEPTOR.
COFACTOR: FAD AND FMN. FAD IS SAID TO BE ASSOCIATED WITH GLPA.
PATHWAY: FIRST STEP IN THE TRANSFER OF REDUCING EQUIVALENTS
FROM G-3-P TO A SHORT ELECTRON TRANSFER CHAIN TERMINATING WITH
FUMARATE AS THE ULTIMATE ELECTRON ACCEPTOR.
SUBUNIT: COMPOSED OF A CATALYTIC GLPA/B DIMER AND OF MEMBRANE
BOUND GLPC.
SUBCELLULAR LOCATION: LOOSELY BOUND TO THE CYTOPLASMIC MEMBRANE
OFTEN OCCURRING IN VESICLES ASSOCIATED WITH FUMARATE REDUCTASE.
SIMILARITY: BELONGS TO THE FAD-DEPENDENT GLYCEROL-3-PHOSPHATE
DEHYDROGENASE FAMILY.
|
| | glpB | b2242 | sn-glycerol-3-phosphate dehydrogenase (anaerobic), membrane anchor subunit |
EG10392 |
FUNCTION: CONVERSION OF GLYCEROL 3-PHOSPHATE TO DIHYDROXYACETONE.
USES FUMARATE OR NITRATE AS ELECTRON ACCEPTOR.
CATALYTIC ACTIVITY: SN-GLYCEROL 3-PHOSPHATE + ACCEPTOR =
GLYCERONEPHOSPHATE + REDUCED ACCEPTOR.
COFACTOR: FMN IS SAID TO BE ASSOCIATED WITH GLPB.
PATHWAY: FIRST STEP IN THE TRANSFER OF REDUCING EQUIVALENTS
FROM G-3-P TO A SHORT ELECTRON TRANSFER CHAIN TERMINATING WITH
FUMARATE AS THE ULTIMATE ELECTRON ACCEPTOR.
SUBUNIT: COMPOSED OF A CATALYTIC GLPA/B DIMER AND OF MEMBRANE
BOUND GLPC.
SUBCELLULAR LOCATION: LOOSELY BOUND TO THE CYTOPLASMIC MEMBRANE
OFTEN OCCURRING IN VESICLES ASSOCIATED WITH FUMARATE REDUCTASE.
SIMILARITY: TO H.INFLUENZAE GLPB.
|
| | glpC | b2243 | sn-glycerol-3-phosphate dehydrogenase (anaerobic), K-small subunit |
EG10393 |
FUNCTION: ELECTRON TRANSFER PROTEIN; MAY ALSO FUNCTION AS THE
MEMBRANE ANCHOR FOR THE GLPAB DIMER.
PATHWAY: FIRST STEP IN THE TRANSFER OF REDUCING EQUIVALENTS
FROM G-3-P TO A SHORT ELECTRON TRANSFER CHAIN TERMINATING WITH
FUMARATE AS THE ULTIMATE ELECTRON ACCEPTOR.
SUBUNIT: COMPOSED OF A CATALYTIC GLPA/B DIMER AND OF GLPC.
SUBCELLULAR LOCATION: LOOSELY BOUND TO THE CYTOPLASMIC MEMBRANE
OFTEN OCCURRING IN VESICLES ASSOCIATED WITH FUMARATE REDUCTASE.
SIMILARITY: THE IRON-SULFUR CENTERS ARE SIMILAR TO THOSE OF
'BACTERIAL-TYPE' 4FE-4S FERREDOXINS.
|
| 0.379062 | - | fur | b0683 | negative regulator |
EG12716 |
CAUTION: REF.1 SEQUENCE DIFFERS FROM THAT SHOWN DUE TO A
FRAMESHIFT IN POSITION 34.
|
| 0.375699 | + | yhiE | b3512 | orf, hypothetical protein |
EG11544 |
|
| 0.373014 | + | csgC | b1043 | putative curli production protein |
EG13414 |
SIMILARITY: STRONG, TO SALMONELLA CSGC.
|
| | b1044 | b1044 | orf, hypothetical protein |
EG13873 |
SIMILARITY: SOME, TO THE N-TERMINAL OF THE FIMA/PAPA FAMILY OF
FIMBRIA PROTEINS.
|
| | b1045 | b1045 | putative polyprotein |
|
|
| | ymdC | b1046 | putative synthase |
EG13875 |
SIMILARITY: BELONGS TO THE PHOSPHOLIPDASE D FAMILY. CARDIOLIPIN
SYNTHASE SUBFAMILY. STRONG, TO H.PYLORI HP0190.
|
| 0.368099 | + | cspF | b1558 | cold shock protein |
EG12205 |
SUBCELLULAR LOCATION: CYTOPLASMIC (BY SIMILARITY).
SIMILARITY: BELONGS TO THE COLD-SHOCK DOMAIN (CSD) FAMILY.
|
| 0.348982 | + | ygaM | b2672 | orf, hypothetical protein |
EG13285 |
SIMILARITY: STRONG, TO E.COLI ELAB AND YQJD.
CAUTION: REF.1 SEQUENCE DIFFERS FROM THAT SHOWN DUE TO A
FRAMESHIFT IN POSITION 80.
|