Score |
Strand | Gene name |
Blattner ID |
Description |
EcoCyc link |
SwissProt comment |
| 2.086927 | - | lipA | b0628 | lipoate synthesis, sulfur insertion? |
EG11306 |
FUNCTION: SYNTHESIS OF ALPHA-(+)-LIPOIC ACID. IT MAY BE INVOLVED
IN THE SULFUR INSERTION CHEMISTRY IN LIPOATE BIOSYNTHESIS.
PATHWAY: LIPOATE BIOSYNTHESIS.
SUBCELLULAR LOCATION: CYTOPLASMIC.
SIMILARITY: BELONGS TO THE BIOTIN AND LIPOIC ACID SYNTHETASES
FAMILY.
|
| 1.600041 | + | rbsK | b3752 | ribokinase |
EG10818 |
CATALYTIC ACTIVITY: ATP + D-RIBOSE = ADP + D-RIBOSE 5-PHOSPHATE.
PATHWAY: FIRST STEP IN RIBOSE METABOLISM.
SUBUNIT: HOMODIMER.
SUBCELLULAR LOCATION: CYTOPLASMIC.
SIMILARITY: BELONGS TO THE PFKB FAMILY OF CARBOHYDRATE KINASES.
|
 | | rbsR | b3753 | regulator for rbs operon |
EG10819 |
FUNCTION: TRANSCRIPTIONAL REPRESSOR FOR THE RIBOSE RBSDACBK
OPERON. RBSR BINDS TO A REGION OF PERFECT DYAD SYMMETRY SPANNING
THE RBS OPERON TRANSCRIPTIONAL START SITE. THE AFFINITY FOR THE
RBS OPERATOR IS REDUCED BY ADDITION OF RIBOSE, CONSISTENT WITH
RIBOSE BEING THE INDUCER OF THE OPERON.
SIMILARITY: BELONGS TO THE LACI FAMILY OF TRANSCRIPTIONAL
REGULATORS.
|
| 0.706628 | - | b1191 | b1191 | orf, hypothetical protein |
EG13896 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE
(POTENTIAL).
SIMILARITY: BELONGS TO THE NA(+)/H(+) EXCHANGER FAMILY.
|
| 0.684710 | - | ygiG | b3058 | putative kinase |
EG11673 |
FUNCTION: CATALYZES THE CONVERSION OF 7,8-DIHYDRONEOPTERIN TO 6-
HYDROXYMETHYL-7,8-DIHYDROPTERIN. CAN USE L-THREO-DIHYDRONEOPTERIN
AND D-ERYTHRO-DIHYDRONEOPTERIN AS SUBSTRATES FOR THE FORMATION OF
6-HYDROXYMETHYLDIHYDROPTERIN, BUT IT CAN ALSO CATALYZE THE
EPIMERIZATION OF CARBON 2' OF DIHYDRONEOPTERIN AND
DIHYDROMONAPTERIN AT APPRECIABLE VELOCITY.
CATALYTIC ACTIVITY: 2-AMINO-4-HYDROXY-6-(D-ERYTHRO-1,2,3-
TRIHYDROXYPROPYL)-7,8-DIHYDROPTERIDINE = 2-AMINO-4-HYDROXY-6-
HYDROXYMETHYL-7,8-DIHYDROPTERIDINE + GLYCOLALDEHYDE.
PATHWAY: FOLATE BIOSYNTHESIS.
SUBUNIT: HOMOOCTAMER.
SIMILARITY: BELONGS TO THE DHNA FAMILY.
|
| | bacA | b3057 | bacitracin resistance; possibly phosphorylates undecaprenol |
EG11665 |
FUNCTION: CONFERS RESISTANCE TO BACITRACIN, PROBABLY BY
PHOSPHORYLATION OF UNDECAPRENOL.
CATALYTIC ACTIVITY: ATP + UNDECAPRENOL = ADP + UNDECAPRENYL
PHOSPHATE.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (PROBABLE).
MISCELLANEOUS: BACITRACIN IS THOUGHT TO BE INVOLVED IN INHIBITION
OF PEPTIDOGLYCAN SYNTHESIS BY SEQUESTERING UNDECAPRENYL
DIPHOSPHATE REDUCING THE POOL OF LIPID CARRIER AVAILABLE.
SIMILARITY: TO A.BRASILENSE BACA.
CAUTION: REF.2 AND REF.3 SEQUENCES DIFFER FROM THAT SHOWN DUE TO
FRAMESHIFTS.
|
| 0.538353 | + | yhhN | b3468 | putative enzyme |
EG12214 |
|
| | zntA | b3469 | zinc-transporting ATPase |
EG12215 |
FUNCTION: INVOLVED IN EXPORT OF LEAD, CADMIUM, ZINC AND MERCURY.
CATALYTIC ACTIVITY: ATP + H(2)O + CD(2+)(IN) = ADP + PHOSPHATE +
CD(2+)(OUT).
CATALYTIC ACTIVITY: ATP + H(2)O + ZN(2+)(IN) = ADP + PHOSPHATE +
ZN(2+)(OUT).
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN.
SIMILARITY: BELONGS TO THE CATION TRANSPORT ATPASES FAMILY
(E1-E2 ATPASES). SUBFAMILY IB.
SIMILARITY: CONTAINS 1 HEAVY-METAL-ASSOCIATED (HMA) DOMAIN.
|
| 0.369995 | + | ygiH | b3059 | orf, hypothetical protein |
EG11674 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
SIMILARITY: BELONGS TO THE UPF0078 FAMILY. STRONG, TO H.INFLUENZAE
HI0266.
|
| 0.343034 | + | prfC | b4375 | peptide chain release factor RF-3 |
EG12114 |
FUNCTION: INCREASES THE FORMATION OF RIBOSOMAL TERMINATION
COMPLEXES AND STIMULATES ACTIVITIES OF RF-1 AND RF-2. IT BINDS
GUANINE NUCLEOTIDES AND HAS STRONG PREFERENCE FOR UGA STOP CODONS.
IT MAY INTERACT DIRECTLY WITH THE RIBOSOME. THE STIMULATION OF RF-
1 AND RF-2 IS SIGNIFICANTLY REDUCED BY GTP AND GDP, BUT NOT BY
GMP.
SUBCELLULAR LOCATION: CYTOPLASMIC.
SIMILARITY: BELONGS TO THE GTP-BINDING ELONGATION FACTOR FAMILY.
PRFC SUBFAMILY.
|
| 0.322340 | + | hyaA | b0972 | hydrogenase-1 small subunit |
EG10468 |
FUNCTION: THIS IS ONE OF THREE E.COLI HYDROGENASES SYNTHESIZED IN
RESPONSE TO DIFFERENT PHYSIOLOGICAL CONDITIONS. HYD1 IS BELIEVED
TO HAVE A ROLE IN HYDROGEN CYCLING DURING FERMENTATIVE GROWTH.
CATALYTIC ACTIVITY: 2 REDUCED FERREDOXIN + 2 H(+) = 2 OXIDIZED
FERREDOXIN + H(2).
COFACTOR: CONTAINS NICKEL AND IRON-SULFUR.
SUBUNIT: HETERODIMER OF A LARGE AND A SMALL SUBUNIT.
SUBCELLULAR LOCATION: MEMBRANE-BOUND; PERIPLASMIC SIDE.
SIMILARITY: TO OTHER UPTAKE HYDROGENASES SMALL SUBUNIT.
|
| | hyaB | b0973 | hydrogenase-1 large subunit |
EG10469 |
FUNCTION: THIS IS ONE OF THREE E.COLI HYDROGENASES SYNTHESIZED IN
RESPONSE TO DIFFERENT PHYSIOLOGICAL CONDITIONS. HYD1 IS BELIEVED
TO HAVE A ROLE IN HYDROGEN CYCLING DURING FERMENTATIVE GROWTH.
CATALYTIC ACTIVITY: 2 REDUCED FERREDOXIN + 2 H(+) = 2 OXIDIZED
FERREDOXIN + H(2).
COFACTOR: CONTAINS NICKEL AND IRON-SULFUR.
SUBUNIT: HETERODIMER OF A LARGE AND A SMALL SUBUNIT.
SUBCELLULAR LOCATION: MEMBRANE-BOUND.
SIMILARITY: BELONGS TO THE [NIFE]/[NIFESE] HYDROGENASE LARGE
SUBUNIT FAMILY.
|
| | hyaC | b0974 | probable Ni/Fe-hydrogenase 1 b-type cytochrome subunit |
EG10470 |
FUNCTION: PROBABLE B-TYPE CYTOCHROME.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE
(POTENTIAL).
SIMILARITY: BELONGS TO THE HUPC/HYAC/HYDC FAMILY.
|
| | hyaD | b0975 | processing of HyaA and HyaB proteins |
EG10471 |
FUNCTION: PROTEASE INVOLVED IN THE C-TERMINAL PROCESSING OF HYAB,
THE LARGE SUBUNIT OF HYDROGENASE 1 (POTENTIAL).
SIMILARITY: BELONGS TO PEPTIDASE FAMILY M52. ALSO KNOWN AS THE
HUPD/HYAD FAMILY.
|
| | hyaE | b0976 | processing of HyaA and HyaB proteins |
EG10472 |
FUNCTION: NOT KNOWN. COULD FORM, ALONG WITH HYAD, A COMPLEX
INVOLVED IN THE PROCESSING OF THE HYDROGENASE 1 STRUCTURAL OPERON.
SIMILARITY: BELONGS TO THE HUPG/HYAE FAMILY.
|
| | hyaF | b0977 | nickel incorporation into hydrogenase-1 proteins |
EG10473 |
FUNCTION: NOT KNOWN. COULD ENHANCE THE INCORPORATION OF NICKEL
TO THE HYDROGENASE.
SIMILARITY: BELONGS TO THE HUPH/HYAF FAMILY.
|
| | appC | b0978 | probable third cytochrome oxidase, subunit I |
EG11380 |
FUNCTION: CYTOCHROME OXIDASE SUBUNIT.
PATHWAY: TERMINAL STEP IN THE RESPIRATORY CHAIN.
SUBUNIT: HETERODIMER OF SUBUNITS I AND II (PROBABLE).
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE
(PROBABLE).
INDUCTION: IS INDUCED WHEN BACTERIAL CULTURES REACH STATIONARY
PHASE; ITS SYNTHESIS IS TRIGGERED BY PHOSPHATE STARVATION OR A
SHIFT FROM AEROBIC TO ANAEROBIC CONDITIONS.
PTM: THE N-TERMINUS IS BLOCKED.
SIMILARITY: STRONG, TO E.COLI CYDA.
|
| | appB | b0979 | probable third cytochrome oxidase, subunit II |
EG11114 |
SIMILARITY: TO E.COLI YBGT.
|
| 0.293908 | + | hemN | b3867 | O2-independent coproporphyrinogen III oxidase |
EG11836 |
FUNCTION: ANAEROBIC TRANSFORMATION OF COPROPORPHYRINOGEN-III INTO
PROTOPORPHYRINOGEN-IX.
COFACTOR: REQUIRES MAGNESIUM, ATP AND NAD (OR NADP) FOR ACTIVITY.
PATHWAY: PORPHYRIN BIOSYNTHESIS.
SUBCELLULAR LOCATION: CYTOPLASMIC.
SIMILARITY: BELONGS TO THE ANAEROBIC COPROPORPHYRINOGEN III
OXIDASE FAMILY.
|
| 0.194841 | + | yjcD | b4064 | orf, hypothetical protein |
EG11939 |
SIMILARITY: STRONG, TO H.INFLUENZAE HI0125.
SIMILARITY: BELONGS TO THE YICO/YIEG/YJCD FAMILY.
|
| 0.187455 | + | ubiG | b2232 | 3-demethylubiquinone-9 3-methyltransferase and 2-octaprenyl-6-hydroxy phenol methylase |
EG11143 |
CATALYTIC ACTIVITY: S-ADENOSYL-L-METHIONINE +
3-DEMETHYLUBIQUINONE-9 = S-ADENOSYL-L-HOMOCYSTEINE +
UBIQUINONE-9.
PATHWAY: UBIQUINONE BIOSYNTHESIS.
SUBUNIT: HOMODIMER (PROBABLE).
SIMILARITY: BELONGS TO THE UBIG/COQ3 FAMILY.
|
| 0.163040 | - | yhhM | b3467 | putative receptor |
EG12213 |
|
| 0.160053 | + | marR | b1530 | multiple antibiotic resistance protein; repressor of mar operon |
EG11435 |
FUNCTION: REPRESSOR OF THE MARRAB OPERON WHICH IS INVOLVED IN THE
ACTIVATION OF BOTH ANTIBIOTIC RESISTANCE AND OXIDATIVE STRESS
GENES. BINDS TO THE MARO OPERATOR/PROMOTER SITE.
SIMILARITY: BELONGS TO THE MARR FAMILY OF TRANSCRIPTIONAL
REGULATORS.
|
| | marA | b1531 | multiple antibiotic resistance; transcriptional activator of defense systems |
EG11434 |
FUNCTION: MAY BE A TRANSCRIPTIONAL ACTIVATOR OF GENES INVOLVED IN
THE MULTIPLE ANTIBIOTIC RESISTANCE (MAR) PHENOTYPE. IT CAN ALSO
ACTIVATE GENES SUCH AS SODA, ZWF AND MICF.
SUBUNIT: MONOMER.
INDUCTION: BY VARIOUS ANTIBIOTICS OR BY SODIUM SALICYLATE.
SIMILARITY: BELONGS TO THE ARAC/XYLS FAMILY OF TRANSCRIPTIONAL
REGULATORS.
CAUTION: IT IS UNCERTAIN WHETHER MET-1 OR MET-3 IS THE INITIATOR.
|
| | marB | b1532 | multiple antibiotic resistance protein |
EG11599 |
|
| 0.157725 | + | div | b2321 | cell division protein |
EG10229 |
|
| 0.156089 | + | yjfG | b4233 | putative ligase |
EG12440 |
FUNCTION: REUTILIZES THE INTACT TRIPEPTIDE L-ALANYL-GAMMA-D-
GLUTAMYL-MESO-DIAMINOPIMELATE BY LINKING IT TO UDP-N-ACETYLMURAMIC
ACID.
PATHWAY: CELL WALL SYNTHESIS; MUREIN TRIPEPTIDE RECYCLING PATHWAY;
LAST STEP.
SIMILARITY: BELONGS TO THE MURCDEF FAMILY.
|
| 0.154683 | + | yfjW | b2642 | orf, hypothetical protein |
EG13209 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
|
| 0.154596 | + | pldA | b3821 | outer membrane phospholipase A |
EG10738 |
FUNCTION: HYDROLYSIS OF PHOSPHATIDYLCHOLINE WITH PHOSPHOLIPASE
A2 (EC 3.1.1.4) AND PHOSPHOLIPASE A1 (EC 3.1.1.32) ACTIVITIES.
REQUIRED FOR EFFICIENT SECRETION OF BACTERIOCINS, SEEMS TO BE
DORMANT IN NORMAL GROWING CELLS.
CATALYTIC ACTIVITY: PHOSPHATIDYLCHOLINE + H(2)O = 1-ACYLGLYCERO-
PHOSPHOCHOLINE + A FATTY ACID ANION.
CATALYTIC ACTIVITY: PHOSPHATIDYLCHOLINE + H(2)O = 2-ACYLGLYCERO-
PHOSPHOCHOLINE + A FATTY ACID ANION.
COFACTOR: REQUIRES CALCIUM IONS FOR ACTIVITY.
SUBCELLULAR LOCATION: OUTER MEMBRANE; ONE OF THE VERY FEW ENZYMES
LOCATED THERE.
INDUCTION: BY MEMBRANE DAMAGING, FOR EXAMPLE, BY PHAGE-INDUCED
LYSIS OR TEMPERATURE SHOCK.
|
| | recQ | b3822 | ATP-dependent DNA helicase |
EG10833 |
FUNCTION: INVOLVED IN THE RECF RECOMBINATION PATHWAY; ITS GENE
EXPRESSION IS UNDER THE REGULATION OF THE SOS SYSTEM. IT IS A DNA
HELICASE.
SIMILARITY: BELONGS TO THE RECQ SUBFAMILY OF HELICASES.
|
| 0.145698 | - | cpdB | b4213 | 2':3'-cyclic-nucleotide 2'-phosphodiesterase |
EG10160 |
FUNCTION: THIS BIFUNCTIONAL ENZYME CATALYZES TWO CONSECUTIVE
REACTIONS CONVERTING 2',3'-CYCLIC-NUCLEOTIDE TO 3'-NUCLEOTIDE
AND THEN 3'-NUCLEOTIDE TO NUCLEIC ACID AND PHOSPHATE.
CATALYTIC ACTIVITY: NUCLEOSIDE 2',3'-CYCLIC PHOSPHATE + H(2)O =
NUCLEOSIDE 3'-PHOSPHATE.
SUBCELLULAR LOCATION: PERIPLASMIC.
MISCELLANEOUS: TWO KINETICALLY DISTINGUISHABLE ACTIVE SITES FOR
TWO CORRESPONDING SUBSTRATES CAN BE IDENTIFIED.
SIMILARITY: BELONGS TO THE 5'-NUCLEOTIDASE FAMILY.
|
| 0.138433 | + | yhcB | b3233 | orf, hypothetical protein |
EG12614 |
SIMILARITY: STRONG, TO H.INFLUENZAE HI1628.
|
| 0.134947 | + | sdaB | b2797 | L-serine dehydratase (deaminase), L-SD2 |
EG11623 |
FUNCTION: DEAMINATES ALSO THREONINE, PARTICULARLY WHEN IT IS
PRESENT IN HIGH CONCENTRATION.
CATALYTIC ACTIVITY: L-SERINE + H(2)O = PYRUVATE + NH(3) + H(2)O.
COFACTOR: IRON-SULFUR (4FE-4S) (PROBABLE).
PATHWAY: GLUCONEOGENESIS FROM SERINE.
INDUCTION: TRANSCRIBED IN RICH MEDIUM, PARTICULARLY IN THE
ABSENCE OF GLUCOSE, AND IS UNDER THE CONTROL OF CATABOLITE
ACTIVATOR PROTEIN. IT IS MADE AEROBICALLY AND ANAEROBICALLY.
PTM: IT IS MADE BY THE CELL IN AN INACTIVE FORM, SUBJECT TO POST-
TRANSLATIONAL ACTIVATION BY A SYSTEM INVOLVING AT LEAST THREE GENE
PRODUCTS. THIS UNKNOWN IN VIVO SYSTEM IS MIMICKED IN VITRO BY IRON
AND DITHIOTHREITOL. THERE IS CONSIDERABLE EVIDENCE FOR A FREE-
RADICAL ACTIVATION MECHANISM.
SIMILARITY: BELONGS TO THE IRON-SULFUR DEPENDENT L-SERINE
DEHYDRATASE FAMILY.
|
| | exo | b2798 | 5'-3' exonuclease |
EG12372 |
FUNCTION: 3'-5' EXONUCLEASE ACTING PREFERENTIALLY ON SINGLE-
STRANDED DNA. ALSO HAS A 3'-PHOSPHODIESTERASE ACTIVITY THAT CAN
REMOVE THE 3'-UNSATURATED SUGAR-PHOSPHATE PRODUCT AT A 3'-INCISED
AP SITE. MAY PLAY AN IMPORTANT ROLE IN BASE EXCISION REPAIR AND
OTHER REPLICATIVE REPAIR AND RECOMBINATION PATHWAYS.
SIMILARITY: HIGH, TO THE EXONUCLEASE DOMAIN OF SOME BACTERIAL
DNA POLYMERASES OF FAMILY A.
|
| 0.133810 | + | chpS | b4224 | suppressor of inhibitory function of ChpB, PemI-like, autoregulated |
EG11250 |
FUNCTION: MAY BE INVOLVED IN THE REGULATION OF CELL GROWTH. IT ACT
AS A SUPPRESSOR OF THE INHIBITORY FUNCTION OF CHPB PROTEIN. BOTH
CHPS AND CHPB BIND TO THE PROMOTER REGION OF THE CHPSB OPERON TO
AUTOREGULATE THEIR SYNTHESIS.
SIMILARITY: BELONGS TO THE PEMI FAMILY.
|
| | chpB | b4225 | probable growth inhibitor, PemK-like, autoregulated |
EG12096 |
FUNCTION: MAY BE INVOLVED IN THE REGULATION OF CELL GROWTH. IT ACT
AS A GROWTH INHIBITOR. BOTH CHPS AND CHPB BIND TO THE PROMOTER
REGION OF THE CHPSB OPERON TO AUTOREGULATE THEIR SYNTHESIS.
SIMILARITY: BELONGS TO THE PEMK FAMILY.
|
| 0.127207 | + | b2444 | b2444 | orf, hypothetical protein |
EG14174 |
|
| | b2445 | b2445 | orf, hypothetical protein |
EG14175 |
|
| | b2446 | b2446 | orf, hypothetical protein |
EG14176 |
|
| | b2447 | b2447 | orf, hypothetical protein |
EG14177 |
|
| 0.121132 | + | ydiS | b1699 | flavoprotein; probably electron transport |
EG13978 |
FUNCTION: PROBABLY ACCEPTS ELECTRONS FROM YDIQ/YDIR AND REDUCES
A QUINONE.
COFACTOR: FAD (POTENTIAL).
SIMILARITY: BELONGS TO THE ETF-QO / FIXC FAMILY.
|
| | ydiT | b1700 | orf, hypothetical protein |
EG13979 |
FUNCTION: COULD BE A 3FE-4S CLUSTER-CONTAINING PROTEIN. PROBABLY
PARTICIPATES IN A REDOX PROCESS WITH YDIQ, YDIR AND YDIS.
SIMILARITY: TO VARIOUS BACTERIAL FERREDOXINS, STRONGEST TO FIXX
FROM NITROGEN FIXING BACTERIA.
|
| | ydiD | b1701 | putative ligase/synthetase |
EG12357 |
SIMILARITY: BELONGS TO THE ATP-DEPENDENT AMP-BINDING ENZYME
FAMILY. STRONG, TO 2,3-DIHYDROXYBENZOATE-AMP LIGASE.
CAUTION: REF.3 SEQUENCE DIFFERS FROM THAT SHOWN DUE TO
FRAMESHIFTS.
|
| 0.119017 | + | appC | b0978 | probable third cytochrome oxidase, subunit I |
EG11380 |
FUNCTION: CYTOCHROME OXIDASE SUBUNIT.
PATHWAY: TERMINAL STEP IN THE RESPIRATORY CHAIN.
SUBUNIT: HETERODIMER OF SUBUNITS I AND II (PROBABLE).
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE
(PROBABLE).
INDUCTION: IS INDUCED WHEN BACTERIAL CULTURES REACH STATIONARY
PHASE; ITS SYNTHESIS IS TRIGGERED BY PHOSPHATE STARVATION OR A
SHIFT FROM AEROBIC TO ANAEROBIC CONDITIONS.
PTM: THE N-TERMINUS IS BLOCKED.
SIMILARITY: STRONG, TO E.COLI CYDA.
|
| | appB | b0979 | probable third cytochrome oxidase, subunit II |
EG11114 |
SIMILARITY: TO E.COLI YBGT.
|
| 0.115871 | - | yjhI | b4299 | putative regulator |
EG12551 |
SIMILARITY: BELONGS TO THE ICLR FAMILY OF TRANSCRIPTIONAL
REGULATORS.
|
| | yjhH | b4298 | putative lyase/synthase |
EG12550 |
SIMILARITY: BELONGS TO THE DHDPS FAMILY. STRONG, TO E.COLI YAGE.
|
| | yjhG | b4297 | putative dehydratase |
EG12549 |
SIMILARITY: BELONGS TO THE ILVD / EDD FAMILY. STRONG, TO E.COLI
YAGF.
|
| | yjhF | b4296 | putative transport system permease |
EG12548 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE
(POTENTIAL).
SIMILARITY: BELONGS TO THE GNTP FAMILY OF PERMEASES.
|
| 0.115840 | - | psd | b4160 | phosphatidylserine decarboxylase; phospholipid synthesis |
EG10775 |
CATALYTIC ACTIVITY: PHOSPHATIDYL-L-SERINE =
PHOSPHATIDYLETHANOLAMINE + CO(2).
COFACTOR: REQUIRES A PYRUVOYL GROUP FOR ITS ACTIVITY.
SUBUNIT: MULTIMER OF THE HETERODIMER.
SUBCELLULAR LOCATION: MEMBRANE-ASSOCIATED.
|
| | yjeP | b4159 | putative periplasmic binding protein |
EG12478 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
SIMILARITY: BELONGS TO THE UPF0003 FAMILY. STRONG, TO H.INFLUENZAE
HI0195.1.
|
| 0.115542 | + | yahD | b0318 | putative transcription factor |
EG13588 |
SIMILARITY: CONTAINS 6 ANK REPEATS.
|
| | yahE | b0319 | orf, hypothetical protein |
EG13589 |
|
| | yahF | b0320 | putative oxidoreductase subunit |
EG13590 |
SIMILARITY: TO E.COLI FDRA AND SOME, TO BACTERIAL SUCD.
|
| | yahG | b0321 | orf, hypothetical protein |
EG13591 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
SIMILARITY: TO E.COLI YLBE.
|
| | yahH | b0322 | orf, hypothetical protein |
EG13592 |
|
| | yahI | b0323 | putative kinase (EC 2.7.2.2). |
EG13593 |
SIMILARITY: BELONGS TO THE CARBAMATE KINASE FAMILY.
|
| | yahJ | b0324 | putative deaminase |
EG13594 |
|
| 0.107876 | + | ybiK | b0828 | putative asparaginase |
EG12407 |
CATALYTIC ACTIVITY: L-ASPARAGINE + H(2)O = L-ASPARTATE + NH(3).
SIMILARITY: BELONGS TO THE ASPARAGINASE 2 FAMILY.
|
| | b0829 | b0829 | putative ATP-binding component of a transport system |
EG13472 |
FUNCTION: PROBABLY PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT
SYSTEM YLIABCD. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE
TRANSPORT SYSTEM.
SIMILARITY: BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY
(ABC TRANSPORTERS).
|
| | b0830 | b0830 | putative transport protein |
EG13473 |
FUNCTION: PROBABLY PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT
SYSTEM YLIABCD.
SUBCELLULAR LOCATION: ATTACHED TO THE MEMBRANE BY A LIPID ANCHOR
(PROBABLE).
SIMILARITY: BELONGS TO THE BACTERIAL EXTRACELLULAR SOLUTE-BINDING
PROTEIN FAMILY 5.
|
| | b0831 | b0831 | putative transport system permease protein |
EG13474 |
FUNCTION: PROBABLY PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT
SYSTEM YLIABCD; PROBABLY RESPONSIBLE FOR THE TRANSLOCATION OF
THE SUBSTRATE ACROSS THE MEMBRANE.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE
(BY SIMILARITY).
SIMILARITY: WITH INTEGRAL MEMBRANE COMPONENTS OF OTHER BINDING-
PROTEIN-DEPENDENT TRANSPORT SYSTEMS. BELONGS TO THE OPPBC
SUBFAMILY.
|
| | b0832 | b0832 | putative transport system permease protein |
EG13475 |
FUNCTION: PROBABLY PART OF A BINDING-PROTEIN-DEPENDENT TRANSPORT
SYSTEM YLIABCD; PROBABLY RESPONSIBLE FOR THE TRANSLOCATION OF
THE SUBSTRATE ACROSS THE MEMBRANE.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE
(BY SIMILARITY).
SIMILARITY: WITH INTEGRAL MEMBRANE COMPONENTS OF OTHER BINDING-
PROTEIN-DEPENDENT TRANSPORT SYSTEMS. BELONGS TO THE OPPBC
SUBFAMILY.
|
| 0.107183 | + | smpB | b2620 | small protein B |
EG11782 |
FUNCTION: BINDS SPECIFICALLY TO THE SSRA RNA (TMRNA) AND IS
REQUIRED FOR STABLE ASSOCIATION OF SSRA WITH RIBOSOMES.
SUBCELLULAR LOCATION: CYTOPLASMIC (POTENTIAL).
SIMILARITY: BELONGS TO THE SSRP FAMILY.
|
| 0.106346 | + | sanA | b2144 | vancomycin sensitivity |
EG12025 |
FUNCTION: PARTICIPATES IN THE BARRIER FUNCTION OF THE CELL
ENVELOPE.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE.
SIMILARITY: STRONG, TO H.INFLUENZAE HI1262.
SIMILARITY: TO E.COLI YGJQ.
|
| | b2145 | b2145 | orf, hypothetical protein |
EG14073 |
|
| 0.103518 | + | yeiR | b2173 | orf, hypothetical protein |
EG12104 |
SIMILARITY: SOME, TO THE 47 KDA PROTEIN (P47K) FROM
P.CHLORORAPHIS.
|
| | b2174 | b2174 | orf, hypothetical protein |
EG14075 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
SIMILARITY: BELONGS TO THE BCRC/YBJG/YWOA FAMILY.
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| 0.103412 | - | yhaQ | b3112 | putative L-serine dehydratase |
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| | yhaP | b3111 | putative L-serine dehydratase |
EG12756 |
CATALYTIC ACTIVITY: L-SERINE + H(2)O = PYRUVATE + NH(3) + H(2)O.
COFACTOR: IRON-SULFUR (4FE-4S) (PROBABLE).
PATHWAY: ANAEROBIC PATHWAY THAT DEGRADES L-THREONINE TO
PROPIONATE.
SIMILARITY: BELONGS TO THE IRON-SULFUR DEPENDENT L-SERINE
DEHYDRATASE FAMILY.
CAUTION: REF.1 SEQUENCE DIFFERS FROM THAT SHOWN DUE TO A
FRAMESHIFT IN POSITION 132 THAT PRODUCES TWO SEPARATE ORFS.
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| 0.102783 | + | intA | b2622 | prophage CP4-57 integrase |
EG11783 |
FUNCTION: INTEGRASE IS NECESSARY FOR INTEGRATION OF THE PHAGE INTO
THE HOST GENOME BY SITE-SPECIFIC RECOMBINATION. IN CONJUNCTION
WITH EXCISIONASE, INTEGRASE IS ALSO NECESSARY FOR EXCISION OF THE
PROPHAGE FROM THE HOST GENOME.
SIMILARITY: BELONGS TO THE "PHAGE" INTEGRASE FAMILY.
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| 0.102220 | + | yqcE | b2775 | putative transport protein |
EG13174 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
SIMILARITY: TO E.COLI YIHN.
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| | ygcE | b2776 | putative kinase |
EG13033 |
SIMILARITY: BELONGS TO THE FUCOKINASE / GLUCONOKINASE /
GLYCEROKINASE / XYLULOKINASE FAMILY.
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| 0.099997 | + | secE | b3981 | preprotein translocase |
EG10939 |
FUNCTION: ESSENTIAL FOR PROTEIN EXPORT.
SUBUNIT: PART OF THE PROKARYOTIC PROTEIN TRANSLOCATION APPARATUS
WHICH COMPRISE SECA, SECB, SECD, SECE, SECF, SECG AND SECY. THE
TRANSLOCATION CHANNEL SEEMS TO BE COMPSOED OF A SECA HOMODIMER AND
FOUR COPIES OF A SECYEG COMPLEX.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE.
SIMILARITY: BELONGS TO THE SECE/SEC61-GAMMA FAMILY.
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| | nusG | b3982 | component in transcription antitermination |
EG10667 |
FUNCTION: INFLUENCES TRANSCRIPTION TERMINATION AND
ANTITERMINATION. ACTS AS A COMPONENT OF THE TRANSCRIPTION COMPLEX,
AND INTERACTS WITH THE TERMINATION FACTOR RHO AND RNA POLYMERASE.
SIMILARITY: BELONGS TO THE NUSG FAMILY.
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