Score |
Strand | Gene name |
Blattner ID |
Description |
EcoCyc link |
SwissProt comment |
| 3.291530 | + | ydgA | b1614 | orf, hypothetical protein |
EG12457 |
SIMILARITY: TO E.COLI YIHF AND H.INFLUENZAE HI1236.
CAUTION: REF.1 SEQUENCE DIFFERS FROM THAT SHOWN FROM POSITION 422
ONWARD AND IS SHORTER (449 AA) DUE TO A FRAMESHIFT.
|
| 2.046479 | + | ydfK | b1544 | orf, hypothetical protein |
 |
|
| 1.663904 | + | ydiE | b1705 | orf, hypothetical protein |
EG12391 |
SIMILARITY: TO Y.ENTEROCOLITICA HEMP.
|
| 1.343365 | + | b2854 | b2854 | orf, hypothetical protein |
|
|
| 1.270352 | + | yrhB | b3446 | orf, hypothetical protein |
EG12948 |
|
| 1.202028 | + | yjfH | b4180 | orf, hypothetical protein |
EG12483 |
SIMILARITY: BELONGS TO THE RNA METHYLTRANSFERASE TRMH FAMILY.
STRONG, TO H.INFLUENZAE HI0860.
|
| | yjfI | b4181 | orf, hypothetical protein |
EG12484 |
|
| | yjfJ | b4182 | putative alpha helical protein |
EG12485 |
|
| | yjfK | b4183 | orf, hypothetical protein |
EG12486 |
|
| | yjfL | b4184 | orf, hypothetical protein |
EG12487 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
|
| | yjfM | b4185 | orf, hypothetical protein |
EG12488 |
|
| | yjfC | b4186 | putative synthetase/amidase |
EG11812 |
SIMILARITY: STRONG, TO THE N-TERMINAL OF E.COLI GSP AND TO E.COLI
YGIC.
|
| | aidB | b4187 | putative acyl coenzyme A dehydrogenase |
EG11811 |
INDUCTION: BY ALKYLATING AGENTS.
SIMILARITY: BELONGS TO THE ACYL-COA DEHYDROGENASES FAMILY.
|
| 1.137110 | - | yheD | b3323 | putative export protein A for general secretion pathway (GSP) |
EG12888 |
FUNCTION: INVOLVED IN A GENERAL SECRETION PATHWAY (GSP) FOR THE
EXPORT OF PROTEINS (BY SIMILARITY).
SIMILARITY: BELONGS TO THE EXEA FAMILY.
|
| | pinO | b3322 | calcium-binding protein required for initiation of chromosome replication |
EG11263 |
FUNCTION: CALCIUM-BINDING PROTEIN THAT MAY BE REQUIRED FOR THE
INITIATION OF CHROMOSOME REPLICATION.
|
| 1.088168 | + | yjdI | b4126 | orf, hypothetical protein |
EG12466 |
|
| | yjdJ | b4127 | orf, hypothetical protein |
EG12467 |
|
| 1.086049 | + | b1820 | b1820 | orf, hypothetical protein |
EG13948 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
|
| 1.073184 | - | fepB | b0592 | ferric enterobactin (enterochelin) binding protein; periplasmic component |
EG10294 |
FUNCTION: BINDS FERRIENTEROBACTIN; PART OF THE BINDING-PROTEIN-
DEPENDENT TRANSPORT SYSTEM FOR UPTAKE OF FERRIENTEROBACTIN.
SUBCELLULAR LOCATION: PERIPLASMIC.
INDUCTION: CONTROLLED IN PART BY THE AMOUNT OF AVAILABLE IRON.
SIMILARITY: BELONGS TO THE BACTERIAL EXTRACELLULAR SOLUTE-BINDING
PROTEIN FAMILY 8.
|
| 0.912832 | + | ygeY | b2872 | putative deacetylase |
EG13055 |
SIMILARITY: BELONGS TO PEPTIDASE FAMILY M20A; ALSO KNOWN AS THE
ARGE/DAPE/ACY1/CPG2/YSCS FAMILY.
|
| | b2873 | b2873 | orf, hypothetical protein |
EG13056 |
SIMILARITY: BELONGS TO THE DEHYDROPYRIMIDINASE FAMILY.
|
| | yqeA | b2874 | putative kinase |
EG13057 |
SIMILARITY: BELONGS TO THE CARBAMATE KINASE FAMILY.
|
| 0.815501 | + | yhaB | b3120 | orf, hypothetical protein |
EG11173 |
|
| | yhaC | b3121 | orf, hypothetical protein |
EG11174 |
|
| | b3122 | b3122 | orf, hypothetical protein |
|
|
| 0.803165 | + | csiE | b2535 | orf, hypothetical protein |
EG13418 |
|
| 0.781713 | + | ygcG | b2778 | orf, hypothetical protein |
EG13035 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
|
| 0.772039 | + | tdcR | b3119 | threonine dehydratase operon activator protein |
EG10992 |
FUNCTION: PROBABLE TRANS-ACTING POSITIVE ACTIVATOR FOR THE TDC
OPERON.
|
| 0.755344 | - | yfbN | b2273 | orf, hypothetical protein |
EG14098 |
|
| 0.674519 | + | csgC | b1043 | putative curli production protein |
EG13414 |
SIMILARITY: STRONG, TO SALMONELLA CSGC.
|
| | b1044 | b1044 | orf, hypothetical protein |
EG13873 |
SIMILARITY: SOME, TO THE N-TERMINAL OF THE FIMA/PAPA FAMILY OF
FIMBRIA PROTEINS.
|
| | b1045 | b1045 | putative polyprotein |
|
|
| | ymdC | b1046 | putative synthase |
EG13875 |
SIMILARITY: BELONGS TO THE PHOSPHOLIPDASE D FAMILY. CARDIOLIPIN
SYNTHASE SUBFAMILY. STRONG, TO H.PYLORI HP0190.
|
| 0.667041 | + | b2505 | b2505 | putative outer membrane lipoprotein |
|
|
| | b2506 | b2506 | putative membrane protein |
EG14205 |
|
| 0.623629 | - | pepA | b4260 | aminopeptidase A/I |
EG10694 |
FUNCTION: REQUIRED FOR PLASMID COLE1 SITE-SPECIFIC RECOMBINATION
BUT NOT IN ITS AMINOPEPTIDASE ACTIVITY. COULD ACT AS A STRUCTURAL
COMPONENT OF THE PUTATIVE NUCLEOPROTEIN COMPLEX IN WHICH THE XER
RECOMBINATION REACTION TAKES PLACE.
CATALYTIC ACTIVITY: AMINOACYL-PEPTIDE + H(2)O = AMINO ACID +
PEPTIDE.
COFACTOR: ACTIVATED BY MANGANESE AND INHIBITED BY ZINC AND EDTA.
SUBUNIT: HOMOHEXAMER.
SIMILARITY: BELONGS TO PEPTIDASE FAMILY M17; ALSO KNOWN AS THE
CYTOSOL AMINOPEPTIDASE FAMILY.
|
| 0.603988 | + | b0609 | b0609 | orf, hypothetical protein |
|
|
| 0.591144 | + | holE | b1842 | DNA polymerase III, theta subunit |
EG11505 |
FUNCTION: DNA POLYMERASE III IS A COMPLEX, MULTICHAIN ENZYME
RESPONSIBLE FOR MOST OF THE REPLICATIVE SYNTHESIS IN BACTERIA.
THIS DNA POLYMERASE ALSO EXHIBITS 3' TO 5' EXONUCLEASE ACTIVITY.
FUNCTION: THE EXACT FUNCTION OF THE THETA SUBUNIT IS UNKNOWN.
CATALYTIC ACTIVITY: N DEOXYNUCLEOSIDE TRIPHOSPHATE =
N PYROPHOSPHATE + DNA(N).
SUBUNIT: CONTAINS A CORE (COMPOSED OF ALPHA, EPSILON, AND THETA
CHAINS) THAT ASSOCIATES WITH A TAU SUBUNIT WHICH ALLOW THE CORE
DIMERIZATION TO FORM THE POLIII' COMPLEX. POLIII' ASSOCIATES WITH
THE GAMMA COMPLEX (COMPOSED OF CHAINS GAMMA, DELTA, DELTA', PSI,
AND CHI) AND WITH THE BETA CHAIN. THE FINAL COMPOSITION OF THE
COMPLEX IS: (ALPHA,EPSILON,THETA)[2]-TAU[2]-(GAMMA,DELTA,DELTA',
PSI,CHI)[2]-BETA[4].
|
| | b1843 | b1843 | orf, hypothetical protein |
EG14030 |
|
| | b1844 | b1844 | orf, hypothetical protein |
EG14031 |
FUNCTION: CAPABLE OF DEGRADING BOTH SINGLE-STRAND AND DOUBLE-
STRAND DNA WITH 3' TO 5' POLARITY. HAS HIGHER AFFINITY FOR SSDNA
ENDS THAN FOR DSDNA. MAY FACILITATE RECOMBINATIONAL REPAIR BY PRE-
SYNAPTIC AND/OR POST-SYNAPTIC DNA DEGRADATION.
COFACTOR: MAGNESIUM-DEPENDENT.
|
| 0.588907 | + | gltF | b3214 | regulator of gltBDF operon, induction of Ntr enzymes |
EG11514 |
FUNCTION: INVOLVED IN INDUCTION OF THE SO-CALLED NTR ENZYMES IN
RESPONSE TO NITROGEN DEPRIVATION, AS WELL AS IN GLUTAMATE
BIOSYNTHESIS. MAY MEDIATE THE GLUTAMATE-DEPENDENT REPRESSION OF
THE GLT OPERON.
SIMILARITY: TO E.COLI YHCF.
|
| 0.587005 | + | sdhC | b0721 | succinate dehydrogenase, cytochrome b556 |
EG10933 |
FUNCTION: MONO-HEME CYTOCHROME OF THE SUCCINATE DEHYDROGENASE
COMPLEX.
PATHWAY: TRICARBOXYLIC ACID CYCLE.
SUBUNIT: PART OF AN ENZYME COMPLEX CONTAINING FOUR SUBUNITS: A
FLAVOPROTEIN, AN IRON-SULFUR, CYTOCHROME B-556, AND AN HYDROPHOBIC
ANCHOR PROTEIN.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE.
SIMILARITY: BELONGS TO THE CYTOCHROME B560 FAMILY.
|
| | sdhD | b0722 | succinate dehydrogenase, hydrophobic subunit |
EG10934 |
FUNCTION: THIS IS THE HYDROPHOBIC COMPONENT OF THE SUCCINATE
DEHYDROGENASE COMPLEX. IT IS SUGGESTED THAT IT IS REQUIRED TO
ANCHOR THE CATALYTIC COMPONENTS TO THE CYTOPLASMIC MEMBRANE.
PATHWAY: TRICARBOXYLIC ACID CYCLE.
SUBUNIT: PART OF AN ENZYME COMPLEX CONTAINING FOUR SUBUNITS: A
FLAVOPROTEIN, AN IRON-SULFUR, CYTOCHROME B-556, AND AN HYDROPHOBIC
ANCHOR PROTEIN.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE.
|
| | sdhA | b0723 | succinate dehydrogenase, flavoprotein subunit |
EG10931 |
FUNCTION: TWO DISTINCT, MEMBRANE-BOUND, FAD-CONTAINING ENZYMES ARE
RESPONSIBLE FOR THE CATALYSIS OF FUMARATE AND SUCCINATE
INTERCONVERSION; THE FUMARATE REDUCTASE IS USED IN ANAEROBIC
GROWTH, AND THE SUCCINATE DEHYDROGENASE IS USED IN AEROBIC GROWTH.
CATALYTIC ACTIVITY: SUCCINATE + ACCEPTOR = FUMARATE + REDUCED
ACCEPTOR.
PATHWAY: TRICARBOXYLIC ACID CYCLE.
SUBUNIT: PART OF AN ENZYME COMPLEX CONTAINING FOUR SUBUNITS: A
FLAVOPROTEIN, AN IRON-SULFUR, CYTOCHROME B-556, AND AN HYDROPHOBIC
ANCHOR PROTEIN.
SIMILARITY: TO THE FLAVOPROTEIN SUBUNITS OF OTHER SPECIES
SUCCINATE DEHYDROGENASE AND OF FUMARATE REDUCTASE.
|
| | sdhB | b0724 | succinate dehydrogenase, iron sulfur protein |
EG10932 |
FUNCTION: TWO DISTINCT, MEMBRANE-BOUND, FAD-CONTAINING ENZYMES ARE
RESPONSIBLE FOR THE CATALYSIS OF FUMARATE AND SUCCINATE
INTERCONVERSION; THE FUMARATE REDUCTASE IS USED IN ANAEROBIC
GROWTH, AND THE SUCCINATE DEHYDROGENASE IS USED IN AEROBIC GROWTH.
CATALYTIC ACTIVITY: SUCCINATE + ACCEPTOR = FUMARATE + REDUCED
ACCEPTOR.
COFACTOR: BINDS THREE DIFFERENT IRON-SULFUR CLUSTERS: A 2FE-2S,
A 3FE-4S AND A 4FE-4S.
PATHWAY: TRICARBOXYLIC ACID CYCLE.
SUBUNIT: PART OF AN ENZYME COMPLEX CONTAINING FOUR SUBUNITS: A
FLAVOPROTEIN, AN IRON-SULFUR, CYTOCHROME B-556, AND AN HYDROPHOBIC
ANCHOR PROTEIN.
SIMILARITY: THE IRON-SULFUR CENTERS ARE SIMILAR TO THOSE OF
'PLANT-TYPE' 2FE-2S AND 'BACTERIAL-TYPE' 4FE-4S FERREDOXINS.
|
| | b0725 | b0725 | orf, hypothetical protein |
|
|
| | sucA | b0726 | 2-oxoglutarate dehydrogenase (decarboxylase component) |
EG10979 |
FUNCTION: THE 2-OXOGLUTARATE DEHYDROGENASE COMPLEX CATALYZES THE
OVERALL CONVERSION OF 2-OXOGLUTARATE TO SUCCINYL-COA & CO(2). IT
CONTAINS MULTIPLE COPIES OF 3 ENZYMATIC COMPONENTS: 2-OXOGLUTARATE
DEHYDROGENASE (E1), DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE (E2) AND
LIPOAMIDE DEHYDROGENASE (E3).
CATALYTIC ACTIVITY: 2-OXOGLUTARATE + LIPOAMIDE = S-SUCCINYL-
DIHYDROLIPOAMIDE + CO(2).
COFACTOR: THIAMINE PYROPHOSPHATE.
SUBUNIT: HOMODIMER.
|
| | sucB | b0727 | 2-oxoglutarate dehydrogenase (dihydrolipoyltranssuccinase E2 component) |
EG10980 |
FUNCTION: THE 2-OXOGLUTARATE DEHYDROGENASE COMPLEX CATALYZES THE
OVERALL CONVERSION OF 2-OXOGLUTARATE TO SUCCINYL-COA & CO(2). IT
CONTAINS MULTIPLE COPIES OF 3 ENZYMATIC COMPONENTS: 2-OXOGLUTARATE
DEHYDROGENASE (E1), DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE (E2) AND
LIPOAMIDE DEHYDROGENASE (E3).
CATALYTIC ACTIVITY: SUCCINYL-COA + DIHYDROLIPOAMIDE = COA +
S-SUCCINYLDIHYDROLIPOAMIDE.
COFACTOR: THE E2 COMPONENT CONTAINS ONE COVALENTLY-BOUND LIPOYL
COFACTOR.
SUBUNIT: FORMS A 24-POLYPEPTIDE STRUCTURAL CORE WITH OCTAHEDRAL
SYMMETRY.
SIMILARITY: BELONGS TO THE 2-OXOACID DEHYDROGENASE FAMILY.
SIMILARITY: CONTAINS 1 LIPOYL-BINDING DOMAIN.
|
| 0.583202 | + | b1966 | b1966 | putative outer membrane protein |
|
|
| 0.566649 | + | yiiG | b3896 | orf, hypothetical protein |
EG11860 |
|
| 0.565024 | + | b1964 | b1964 | putative outer membrane protein |
EG14042 |
SUBUNIT: HOMOTRIMER (BY SIMILARITY).
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. OUTER MEMBRANE
(BY SIMILARITY).
SIMILARITY: BELONGS TO THE OMPC/PHOE FAMILY OF PORINS.
CAUTION: THIS IS A CONCEPTUAL TRANSLATION, AN IN-FRAME STOP CODON
WAS READ OVER IN POSITION 162 AND TWO POTENTIAL FRAMESHIFTS WERE
CORRECTED.
|
| | b1965 | b1965 | orf, hypothetical protein |
|
|
| | b1966 | b1966 | putative outer membrane protein |
|
|
| 0.527193 | - | yicO | b3664 | orf, hypothetical protein |
EG11691 |
SIMILARITY: BELONGS TO THE YICO/YIEG/YJCD FAMILY.
|
| | yicN | b3663 | orf, hypothetical protein |
EG11690 |
|
| | yicM | b3662 | putative transport protein |
EG11689 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE
(POTENTIAL).
|
| 0.515397 | + | yffB | b2471 | orf, hypothetical protein |
EG11147 |
SIMILARITY: STRONG, TO H.INFLUENZAE HI0103.
|
| | dapE | b2472 | N-succinyl-diaminopimelate deacylase |
EG10208 |
CATALYTIC ACTIVITY: N-SUCCINYL-LL-2,6-DIAMINOHEPTANEDIOATE + H(2)O
= SUCCINATE + LL-2,6-DIAMINOHEPTANEDIOATE.
COFACTOR: COBALT OR ZINC.
PATHWAY: FIFTH STEP IN THE BIOSYNTHESIS OF DIAMINOPIMELATE AND
LYSINE FROM ASPARTATE SEMIALDEHYDE.
MISCELLANEOUS: DAPE/MSGB IS A MULTICOPY SUPPRESSOR OF A
TEMPERATURE-SENSITIVE ALLELE OF THE HEAT SHOCK GENE GRPE.
SIMILARITY: BELONGS TO PEPTIDASE FAMILY M20B; ALSO KNOWN AS THE
ARGE/DAPE/ACY1/CPG2/YSCS FAMILY.
|
| 0.515310 | + | ynaJ | b1332 | orf, hypothetical protein |
EG14294 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
|
| 0.513474 | + | sbcB | b2011 | exonuclease I, 3' --> 5' specific; deoxyribophosphodiesterase |
EG10926 |
FUNCTION: ALSO FUNCTIONS AS A DNA DEOXYRIBOPHOSPHODIESTERASE THAT
RELEASE DEOXYRIBOSE-PHOSPHATE MOIETIES FOLLOWING THE CLEAVAGE DNA
AT AN APURINIC/APYRIMIDINIC (AP) SITE BY EITHER AN AP ENDONUCLEASE
AP LYASE.
CATALYTIC ACTIVITY: DEGRADATION OF SINGLE-STRANDED DNA.
IT ACTS PROGRESSIVELY IN A 3' TO 5' DIRECTION, RELEASING
5'-PHOSPHOMONONUCLEOTIDES.
|
| 0.502225 | + | marR | b1530 | multiple antibiotic resistance protein; repressor of mar operon |
EG11435 |
FUNCTION: REPRESSOR OF THE MARRAB OPERON WHICH IS INVOLVED IN THE
ACTIVATION OF BOTH ANTIBIOTIC RESISTANCE AND OXIDATIVE STRESS
GENES. BINDS TO THE MARO OPERATOR/PROMOTER SITE.
SIMILARITY: BELONGS TO THE MARR FAMILY OF TRANSCRIPTIONAL
REGULATORS.
|
| | marA | b1531 | multiple antibiotic resistance; transcriptional activator of defense systems |
EG11434 |
FUNCTION: MAY BE A TRANSCRIPTIONAL ACTIVATOR OF GENES INVOLVED IN
THE MULTIPLE ANTIBIOTIC RESISTANCE (MAR) PHENOTYPE. IT CAN ALSO
ACTIVATE GENES SUCH AS SODA, ZWF AND MICF.
SUBUNIT: MONOMER.
INDUCTION: BY VARIOUS ANTIBIOTICS OR BY SODIUM SALICYLATE.
SIMILARITY: BELONGS TO THE ARAC/XYLS FAMILY OF TRANSCRIPTIONAL
REGULATORS.
CAUTION: IT IS UNCERTAIN WHETHER MET-1 OR MET-3 IS THE INITIATOR.
|
| | marB | b1532 | multiple antibiotic resistance protein |
EG11599 |
|
| 0.490322 | + | yicP | b3665 | probable adenine deaminase (synthesis xanthine) |
EG11692 |
CATALYTIC ACTIVITY: ADENINE + H(2)O = HYPOXANTHINE + NH(3).
SIMILARITY: BELONGS TO THE ADENINE AMINASE FAMILY.
|
| 0.488215 | + | rplL | b3986 | 50S ribosomal subunit protein L7/L12 |
EG10873 |
FUNCTION: SEEMS TO BE THE BINDING SITE FOR SEVERAL OF THE FACTORS
INVOLVED IN PROTEIN SYNTHESIS AND APPEARS TO BE ESSENTIAL FOR
ACCURATE TRANSLATION.
SUBUNIT: L7/L12 FORM DIMERS WITH AN ELONGATED SHAPE. TWO DIMERS
ASSOCIATE WITH A COPY OF L10 TO FORM A VERY STRONG COMPLEX (CALLED
L8).
PTM: THE ONLY DIFFERENCE BETWEEN L7 AND L12, IS THAT IN L7 THE
AMINO END IS ACETYLATED.
MASS SPECTROMETRY: MW=12206.7; METHOD=MALDI.
SIMILARITY: BELONGS TO THE L12P FAMILY OF RIBOSOMAL PROTEINS.
|
| 0.462460 | + | fes | b0585 | enterochelin esterase |
EG14353 |
FUNCTION: COULD BE INVOLVED IN ENTEROBACTIN SYNTHESIS.
SIMILARITY: TO M.TUBERCULOSIS MBTH.
|
| 0.451380 | + | cspE | b0623 | cold shock protein |
EG12179 |
SUBCELLULAR LOCATION: CYTOPLASMIC (BY SIMILARITY).
MASS SPECTROMETRY: MW=7333.8; METHOD=MALDI.
SIMILARITY: BELONGS TO THE COLD-SHOCK DOMAIN (CSD) FAMILY.
|