Score |
Strand | Gene name |
Blattner ID |
Description |
EcoCyc link |
SwissProt comment |
| 10.590830 | - | gntK | b3437 | gluconokinase 2, thermoresistant |
EG12629 |
CATALYTIC ACTIVITY: ATP + D-GLUCONATE = ADP + 6-PHOSPHO-D-
GLUCONATE.
PATHWAY: PART OF THE GLUCONATE UTILIZATION SYSTEM GNT-I.
CAUTION: REF.2 SEQUENCE DIFFERS FROM THAT SHOWN DUE TO A
FRAMESHIFT.
|
 | | gntU_1 | b3436 | low-affinity gluconate transport permease protein, interrupted |
|
|
| | gntU_2 | b3435 | low-affinity gluconate transport permease protein, fragment 2 |
EG12631 |
FUNCTION: PART OF THE GLUCONATE UTILIZATION SYSTEM GNT-I; LOW-
AFFINITY INTAKE OF GLUCONATE.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE
(POTENTIAL).
SIMILARITY: BELONGS TO THE GNTP FAMILY OF PERMEASES.
CAUTION: REF.2 SEQUENCE DIFFERS FROM THAT SHOWN DUE TO A
FRAMESHIFT.
|
| 5.514611 | - | edd | b1851 | 6-phosphogluconate dehydratase |
EG10257 |
CATALYTIC ACTIVITY: 6-PHOSPHO-D-GLUCONATE = 6-PHOSPHO-2-DEHYDRO-
3-DEOXY-D-GLUCONATE + H(2)O.
PATHWAY: KEY ENZYME IN THE ENTNER-DOUDOROFF PATHWAY.
INDUCTION: BY GROWTH ON GLUCONATE.
SIMILARITY: BELONGS TO THE ILVD / EDD FAMILY.
|
| | eda | b1850 | 2-keto-3-deoxygluconate 6-phosphate aldolase and 2-keto-4-hydroxyglutarate aldolase |
EG10256 |
CATALYTIC ACTIVITY: 4-HYDROXY-2-OXOGLUTARATE = PYRUVATE +
GLYOXYLATE.
CATALYTIC ACTIVITY: 2-DEHYDRO-3-DEOXY-D-GLUCONATE 6-PHOSPHATE =
PYRUVATE + D-GLYCERALDEHYDE 3-PHOSPHATE.
PATHWAY: KEY ENZYME IN THE ENTNER-DOUDOROFF PATHWAY.
PATHWAY: PARTICIPATES IN THE REGULATION OF THE INTRACELLULAR LEVEL
OF GLYOXYLATE.
SUBUNIT: HOMOTRIMER.
SUBCELLULAR LOCATION: CYTOPLASMIC.
INDUCTION: CONSTITUTIVE, THREEFOLD INDUCTION OCCURS FOR GROWTH
ON GLUCONATE AND TWOFOLD FOR GROWTH ON HEXURONIC ACIDS.
MISCELLANEOUS: IT ALSO CATALYZES THE BETA-DECARBOXYLATION OF
OXALOACETATE.
SIMILARITY: BELONGS TO THE KHG/KDPG ALDOLASE FAMILY.
|
| 4.658269 | - | hemL | b0154 | glutamate-1-semialdehyde aminotransferase (aminomutase) |
EG10432 |
CATALYTIC ACTIVITY: (S)-4-AMINO-5-OXOPENTANOATE =
5-AMINOLEVULINATE.
COFACTOR: PYRIDOXAL PHOSPHATE.
PATHWAY: PORPHYRIN BIOSYNTHESIS BY THE C5 PATHWAY; SECOND STEP.
SUBUNIT: HOMODIMER.
SUBCELLULAR LOCATION: CYTOPLASMIC (POTENTIAL).
SIMILARITY: BELONGS TO CLASS-III OF PYRIDOXAL-PHOSPHATE-DEPENDENT
AMINOTRANSFERASES.
|
| 4.348222 | + | yraM | b3147 | putative glycosylase |
EG12778 |
SIMILARITY: STRONG, TO H.INFLUENZAE HI1655.
|
| | yraN | b3148 | orf, hypothetical protein |
EG12779 |
SIMILARITY: BELONGS TO THE UPF0102 FAMILY. STRONG, TO H.INFLUENZAE
HI1656.
|
| | yraO | b3149 | orf, hypothetical protein |
EG12780 |
SIMILARITY: BELONGS TO THE SIS FAMILY. YRAO SUBFAMILY.
|
| | yraP | b3150 | putative periplasmic protein |
EG12781 |
SUBCELLULAR LOCATION: PERIPLASMIC (POTENTIAL).
SIMILARITY: STRONG, TO H.INFLUENZAE HI1658.
SIMILARITY: STRONG, TO E.COLI OSMY AND A.PLEUROPNEUMONIAE HLY.
|
| 3.650720 | + | fes | b0585 | enterochelin esterase |
EG14353 |
FUNCTION: COULD BE INVOLVED IN ENTEROBACTIN SYNTHESIS.
SIMILARITY: TO M.TUBERCULOSIS MBTH.
|
| 3.261752 | - | fepA | b0584 | outer membrane receptor for ferric enterobactin (enterochelin) and colicins B and D |
EG10293 |
FUNCTION: THIS PROTEIN IS INVOLVED IN THE INITIAL STEP OF IRON
UPTAKE BY BINDING FERRIENTEROBACTIN (FE-ENT), AN IRON CHELATIN
SIDEROPHORE THAT ALLOWS E.COLI TO EXTRACT IRON FROM THE
ENVIRONMENT. FEPA ALSO ACTS AS A RECEPTOR FOR COLICINS B AND D.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. OUTER MEMBRANE.
SIMILARITY: LOCAL TO OTHER TONB-DEPENDENT RECEPTOR PROTEINS.
|
| 3.116614 | + | gntT | b3415 | high-affinity transport of gluconate / gluconate permease |
EG12380 |
FUNCTION: PART OF THE GLUCONATE UTILIZATION SYSTEM GNT-I; HIGH-
AFFINITY INTAKE OF GLUCONATE.
PATHWAY: GLUCONATE UTILIZATION.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE
(POTENTIAL).
SIMILARITY: BELONGS TO THE GNTP FAMILY OF PERMEASES.
|
| 2.939052 | + | yadQ | b0155 | putative channel transporter |
EG12331 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (PROBABLE).
SIMILARITY: TO YEAST GEF1 AND TO CHLORIDE CHANNEL PROTEINS.
CAUTION: REF.1 SEQUENCE DIFFERS FROM THAT SHOWN DUE TO A
FRAMESHIFT IN POSITION 11.
|
| | yadR | b0156 | orf, hypothetical protein |
EG12332 |
SIMILARITY: BELONGS TO THE HESB/YADR/YFHF FAMILY. STRONG, TO
H.INFLUENZAE HI1723.
|
| 2.938635 | + | dicA | b1570 | regulator of dicB |
EG10226 |
FUNCTION: THIS PROTEIN IS A REPRESSOR OF DIVISION INHIBITION
GENE DICB.
|
| 2.780794 | - | b2997 | b2997 | putative hydrogenase subunit |
EG13006 |
FUNCTION: THIS IS ONE OF THREE E.COLI HYDROGENASES SYNTHESIZED IN
RESPONSE TO DIFFERENT PHYSIOLOGICAL CONDITIONS. HYD2 IS INVOLVED
IN HYDROGEN UPTAKE.
CATALYTIC ACTIVITY: 2 REDUCED FERREDOXIN + 2 H(+) = 2 OXIDIZED
FERREDOXIN + H(2).
COFACTOR: CONTAINS NICKEL AND IRON-SULFUR.
SUBUNIT: HETERODIMER OF A LARGE AND A SMALL SUBUNIT.
SUBCELLULAR LOCATION: MEMBRANE-BOUND; PERIPLASMIC SIDE.
SIMILARITY: TO OTHER UPTAKE HYDROGENASES SMALL SUBUNIT.
|
| | hybA | b2996 | hydrogenase-2 small subunit |
EG11799 |
FUNCTION: PARTICIPATES IN THE PERIPLASMIC ELECTRON-TRANSFERRING
ACTIVITY OF HYDROGENASE 2 DURING ITS CATALYTIC TURNOVER.
COFACTOR: BINDS 3 4FE-4S CLUSTERS AND A 3FE-4S CLUSTER.
SUBCELLULAR LOCATION: PERIPLASMIC.
SIMILARITY: THE IRON-SULFUR CENTERS ARE SIMILAR TO THOSE OF
'BACTERIAL-TYPE' 4FE-4S FERREDOXINS.
CAUTION: WAS ORIGINALLY (REF.1) THOUGHT TO BE THE SMALL SUBUNIT
OF HYDROGENASE 2.
|
| | hybB | b2995 | probable cytochrome Ni/Fe component of hydrogenase-2 |
EG11800 |
FUNCTION: PROBABLE B-TYPE CYTOCHROME.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN.
|
| | hybC | b2994 | probable large subunit, hydrogenase-2 |
EG11801 |
FUNCTION: THIS IS ONE OF THREE E.COLI HYDROGENASES SYNTHESIZED IN
RESPONSE TO DIFFERENT PHYSIOLOGICAL CONDITIONS. HYD2 IS INVOLVED
IN HYDROGEN UPTAKE.
CATALYTIC ACTIVITY: 2 REDUCED FERREDOXIN + 2 H(+) = 2 OXIDIZED
FERREDOXIN + H(2).
COFACTOR: CONTAINS NICKEL AND IRON-SULFUR.
SUBUNIT: HETERODIMER OF A LARGE AND A SMALL SUBUNIT.
SUBCELLULAR LOCATION: MEMBRANE-BOUND.
SIMILARITY: BELONGS TO THE [NIFE]/[NIFESE] HYDROGENASE LARGE
SUBUNIT FAMILY.
|
| | hybD | b2993 | probable processing element for hydrogenase-2 |
EG11802 |
FUNCTION: PROTEASE INVOLVED IN THE C-TERMINAL PROCESSING OF HYBC,
THE LARGE SUBUNIT OF HYDROGENASE 2. SPECIFICALLY CLEAVES OFF A 15
AMINO ACID PEPTIDE FROM THE C TERMINUS OF THE PRECURSOR OF HYBC.
COFACTOR: NICKEL.
SIMILARITY: BELONGS TO PEPTIDASE FAMILY M52. ALSO KNOWN AS THE
HUPD/HYAD FAMILY.
|
| | hybE | b2992 | member of hyb operon |
EG11803 |
SIMILARITY: BELONGS TO THE HUPJ FAMILY.
|
| | hybF | b2991 | may modulate levels of hydrogenease-2 |
EG11804 |
FUNCTION: PROBABLY PLAYS A ROLE IN AN HYDROGENASE NICKEL COFACTOR
INSERTION STEP.
SIMILARITY: BELONGS TO THE HYPA/HYBF FAMILY.
CAUTION: REF.1 SEQUENCE WAS TRANSLATED FROM THE WRONG OPEN
READING FRAME.
|
| | hybG | b2990 | hydrogenase-2 operon protein: may effect maturation of large subunit of hydrogenase-2 |
EG11805 |
FUNCTION: MAY HAVE A SPECIFIC ROLE IN THE MATURATION OF THE LARGE
SUBUNITS OF HYD1 AND HYD2.
SIMILARITY: BELONGS TO THE HUPF/HYPC FAMILY.
|
| 2.615624 | + | yhiE | b3512 | orf, hypothetical protein |
EG11544 |
|
| 2.603257 | - | dicC | b1569 | regulator of dicB |
EG10228 |
FUNCTION: THIS PROTEIN IS A REPRESSOR OF DIVISION INHIBITION
GENE DICB.
|
| | b1568 | b1568 | orf, hypothetical protein |
EG13836 |
|
| | b1567 | b1567 | orf, hypothetical protein |
EG13835 |
|
| 2.061093 | - | poxB | b0871 | pyruvate oxidase |
EG10754 |
CATALYTIC ACTIVITY: PYRUVATE + FERRICYTOCHROME B1 + H(2)O = CO(2)
+ ACETATE + FERROCYTOCHROME B1.
COFACTOR: THIAMINE PYROPHOSPHATE, FAD AND MAGNESIUM ION.
SUBUNIT: HOMOTETRAMER.
SUBCELLULAR LOCATION: MEMBRANE-ASSOCIATED.
PTM: ACTIVATED BY LIMITED PROTEOLYTIC DIGESTION. THIS CLEAVAGE
PRODUCES A PEPTIDE (ALPHA-PEPTIDE) AND MIMICS THE ACTIVATION OF
ENZYME BY PHOSPHOLIPIDS. THE PROTEOLYTIC CLEAVAGE ALSO RESULTS IN
THE LOSS OF THE HIGH AFFINITY LIPID-BINDING SITE OF THE ENZYME.
SIMILARITY: WITH OTHER ENZYMES WHICH REQUIRE TPP.
|
| | ybjU | b0870 | putative arylsulfatase |
EG13690 |
FUNCTION: STEREOSPECIFICALLY CATALYZES THE INTERCONVERSION OF L-
ALLO-THREONINE AND GLYCINE (BY SIMILARITY).
CATALYTIC ACTIVITY: L-ALLO-THREONINE = GLYCINE + ACETALDEHYDE.
COFACTOR: PYRIDOXAL PHOSPHATE (BY SIMILARITY).
SIMILARITY: BELONGS TO THE THREONINE ALDOLASE FAMILY.
|
| | ybjT | b0869 | putative dTDP-glucose enzyme |
EG13689 |
|
| | b0868 | b0868 | putative nucleotide di-P-sugar epimerase or dehydratase |
|
|
| 1.926841 | - | idnD | b4267 | L-idonate dehydrogenase |
EG12541 |
FUNCTION: CATALYZE THE NADH/NADPH-DEPENDENT OXIDATION OF L-IDONATE
TO 5-KETOGLUCONATE (5KG).
PATHWAY: PART OF THE GLUCONATE UTILIZATION SYSTEM GNT-II.
SIMILARITY: BELONGS TO THE ZINC-CONTAINING ALCOHOL DEHYDROGENASE
FAMILY.
|
| | idnO | b4266 | 5-keto-D-gluconate 5-reductase |
EG12540 |
FUNCTION: CATALYZES A REVERSIBLE REDUCTION OF 5-KETOGLUTANATE TO
FORM D-GLUCONATE. DEPENDENT ON NADP, ALMOST INACTIVE WITH NAD.
CATALYTIC ACTIVITY: D-GLUCONATE + NAD(P)(+) = 5-DEHYDRO-D-
GLUCONATE + NAD(P)H.
PATHWAY: PART OF THE GLUCONATE UTILIZATION SYSTEM GNT-II.
SUBCELLULAR LOCATION: CYTOPLASMIC (PROBABLE).
SIMILARITY: BELONGS TO THE SHORT-CHAIN DEHYDROGENASES/REDUCTASES
(SDR) FAMILY.
|
| | idnT | b4265 | L-idonate transporter |
EG12539 |
FUNCTION: TRANSPORT OF GLUCONATE AND L-IDONATE.
PATHWAY: PART OF THE GLUCONATE UTILIZATION SYSTEM GNT-II.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE
(POTENTIAL).
SIMILARITY: BELONGS TO THE GNTP FAMILY OF PERMEASES.
|
| | idnR | b4264 | L-idonate transcriptional regulator |
EG12538 |
FUNCTION: IDN OPERON REGULATOR. MAY REPRESS GNTKU AND GNTT GENES
WHEN GROWING ON L-IDONATE.
SIMILARITY: BELONGS TO THE LACI FAMILY OF TRANSCRIPTIONAL
REGULATORS.
|
| | yjgR | b4263 | orf, hypothetical protein |
EG12537 |
SIMILARITY: TO E.COLI YJIB.
|
| 1.920771 | + | idnK | b4268 | gluconate kinase, thermosensitive glucokinase |
EG12152 |
CATALYTIC ACTIVITY: ATP + D-GLUCONATE = ADP + 6-PHOSPHO-D-
GLUCONATE.
PATHWAY: PART OF THE GLUCONATE UTILIZATION SYSTEM GNT-II.
|
| 1.791259 | + | yjeN | b4157 | orf, hypothetical protein |
EG12476 |
|
| | yjeO | b4158 | orf, hypothetical protein |
EG12477 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
|
| 1.701880 | + | b1978 | b1978 | putative factor |
|
|
| 1.572752 | + | ygcG | b2778 | orf, hypothetical protein |
EG13035 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
|
| 1.568670 | - | b1448 | b1448 | putative resistance protein |
EG13770 |
SIMILARITY: BELONGS TO THE ACETYLTRANSFERASE FAMILY. PAT/BAR
SUBFAMILY.
|
| | b1447 | b1447 | orf, hypothetical protein |
EG13769 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
|
| 1.422000 | + | yohJ | b2141 | orf, hypothetical protein |
EG12023 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
SIMILARITY: BELONGS TO THE YOHJ (E.COLI) / YWBH (IPA-23R)
(B.SUBTILIS) FAMILY.
|
| | yohK | b2142 | putative seritonin transporter |
EG12024 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
SIMILARITY: BELONGS TO THE YOHK (E.COLI) / YWBG (IPA-22R)
(B.SUBTILIS) FAMILY.
|
| | cdd | b2143 | cytidine/deoxycytidine deaminase |
EG10137 |
FUNCTION: THIS ENZYME SCAVENGE EXOGENOUS AND ENDOGENOUS CYTIDINE
AND 2'-DEOXYCYTIDINE FOR UMP SYNTHESIS.
CATALYTIC ACTIVITY: CYTIDINE + H(2)O = URIDINE + NH(3).
COFACTOR: TIGHTLY BIND A SINGLE ATOM OF ZINC.
SUBUNIT: HOMODIMER.
DOMAIN: EACH MONOMER IS COMPOSED OF A SMALL N-TERMINAL ALPHA-
HELICAL DOMAIN AND TWO LARGER CORE DOMAINS THAT HAVE NEARLY
IDENTICAL TERTIARY STRUCTURES AND ARE RELATED BY APPROXIMATE TWO-
FOLD SYMMETRY, BUT LACK AA HOMOLOGY.
SIMILARITY: BELONGS TO THE CYTIDINE AND DEOXYCYTIDYLATE DEAMINASES
FAMILY.
CAUTION: REF.2 SEQUENCE DIFFERS FROM THAT SHOWN FROM POSITION 255
ONWARD AND IS LONGER (330 AA) DUE TO A FRAMESHIFT.
|
| 1.420808 | + | xseA | b2509 | exonuclease VII, large subunit |
EG11072 |
FUNCTION: BIDIRECTIONALLY DEGRADES SINGLE-STRANDED DNA INTO LARGE
ACID-INSOLUBLE OLIGONUCLEOTIDES, WHICH ARE THEN DEGRADED FURTHER
INTO SMALL ACID-SOLUBLE OLIGONUCLEOTIDES. IT CAN ALSO DEGRADE 3'
OR 5' SS REGIONS EXTENDING FROM THE TERMINI OF DUPLEX DNA
MOLECULES AND DISPLACED SS REGIONS.
CATALYTIC ACTIVITY: EXONUCLEOLYTIC CLEAVAGE IN EITHER 5'-TO 3'-OR
3'-TO 5'-DIRECTION TO YIELD 5'-PHOSPHOMONONUCLEOTIDES.
SUBUNIT: HETEROOLIGOMER COMPOSED OF TWO DIFFERENT SUBUNITS WITH
AN APPROXIMATE RATIO OF 4 SMALL SUBUNITS FOR 1 LARGE.
SUBCELLULAR LOCATION: CYTOPLASMIC.
SIMILARITY: BELONGS TO THE XSEA FAMILY.
|
| 1.409375 | + | creA | b4397 | orf, hypothetical protein |
EG11217 |
|
| | creB | b4398 | catabolic regulation response regulator |
EG11218 |
FUNCTION: MEMBER OF THE TWO-COMPONENT REGULATORY SYSTEM CREC/CREB
INVOLVED IN CATABOLIC REGULATION.
SUBCELLULAR LOCATION: CYTOPLASMIC (PROBABLE).
PTM: PHOSPHORYLATED BY CREC (PROBABLE).
SIMILARITY: TO OTHER BACTERIAL REGULATORY PROTEINS INVOLVED IN
SIGNAL TRANSDUCTION.
|
| | creC | b4399 | catabolite repression sensor kinase for PhoB; alternative sensor for pho regulon |
EG10730 |
FUNCTION: MEMBER OF THE TWO-COMPONENT REGULATORY SYSTEM CREC/CREB
INVOLVED IN CATABOLIC REGULATION. CREC MAY FUNCTION AS A MEMBRANE-
ASSOCIATED PROTEIN KINASE THAT PHOSPHORYLATES CREB IN RESPONSE TO
ENVIRONMENTAL SIGNALS. CREC CAN ALSO PHOSPHORYLATES PHOB.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE
(PROBABLE).
SIMILARITY: TO OTHER PROKARYOTIC SENSORY TRANSDUCTION HISTIDINE
KINASES.
|
| | creD | b4400 | tolerance to colicin E2 |
EG10145 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE.
MISCELLANEOUS: MUTATIONS OF THIS GENE LEADS TO A ENHANCED
TRANSCRIPTION OF THE GENE CAUSE TOLERANCE TO COLICIN E2.
|
| 1.383258 | + | yjjY | b4402 | orf, hypothetical protein |
EG12601 |
|
| 1.315534 | - | glpE | b3425 | protein of glp regulon |
EG10395 |
FUNCTION: NOT YET KNOWN.
|
| | glpG | b3424 | protein of glp regulon |
EG10397 |
FUNCTION: NOT YET KNOWN.
|
| | glpR | b3423 | repressor of the glp operon |
EG10400 |
FUNCTION: REPRESSOR OF THE GLYCEROL-3-PHOSPHATE REGULON.
SIMILARITY: BELONGS TO THE DEOR FAMILY OF TRANSCRIPTIONAL
REGULATORS.
CAUTION: REF.2 SEQUENCE DIFFERS FROM THAT SHOWN DUE TO
FRAMESHIFTS.
|
| 1.282564 | + | yjgP | b4261 | orf, hypothetical protein |
EG12535 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
SIMILARITY: STRONG, TO H.INFLUENZAE HI1704.
|
| | yjgQ | b4262 | orf, hypothetical protein |
EG12536 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
SIMILARITY: STRONG, TO H.INFLUENZAE HI1703.
|
| 1.280469 | + | yncB | b1449 | putative oxidoreductase |
EG13772 |
SIMILARITY: BELONGS TO THE L4BD FAMILY OF NADP-DEPENDENT
OXIDOREDUCTASE.
|
| | b1450 | b1450 | orf, hypothetical protein |
EG13773 |
SIMILARITY: BELONGS TO THE GNTR FAMILY OF TRANSCRIPTIONAL
REGULATORS.
|
| 1.261133 | - | yheO | b3346 | orf, hypothetical protein |
EG12899 |
SIMILARITY: STRONG, TO H.INFLUENZAE HI0575.
|
| | yheN | b3345 | orf, hypothetical protein |
EG12898 |
SIMILARITY: BELONGS TO THE UPF0163 (DSRE) FAMILY.
|
| | yheM | b3344 | orf, hypothetical protein |
EG12897 |
SIMILARITY: BELONGS TO THE UPF0116 (DSRF) FAMILY.
|
| | yheL | b3343 | orf, hypothetical protein |
EG12896 |
SIMILARITY: STRONG, TO B.APHIDICOLA (SUBSP. ACYRTHOSIPHON PISUM)
BU530.
|
| | rpsL | b3342 | 30S ribosomal subunit protein S12 |
EG10911 |
FUNCTION: PROTEIN S12 IS INVOLVED IN THE TRANSLATION INITIATION
STEP.
MASS SPECTROMETRY: MW=13651.3; METHOD=MALDI.
SIMILARITY: BELONGS TO THE S12P FAMILY OF RIBOSOMAL PROTEINS.
|
| | rpsG | b3341 | 30S ribosomal subunit protein S7, initiates assembly |
EG10906 |
FUNCTION: PROTEIN S7 BINDS SPECIFICALLY TO PART OF THE 3' END OF
16S RIBOSOMAL RNA.
MASS SPECTROMETRY: MW=19888.7; METHOD=MALDI.
MISCELLANEOUS: THE STRAIN K12 SEQUENCE IS SHOWN.
SIMILARITY: BELONGS TO THE S7P FAMILY OF RIBOSOMAL PROTEINS.
|
| | fusA | b3340 | GTP-binding protein chain elongation factor EF-G |
EG10360 |
FUNCTION: THIS PROTEIN PROMOTES THE GTP-DEPENDENT TRANSLOCATION
OF THE NASCENT PROTEIN CHAIN FROM THE A-SITE TO THE P-SITE OF THE
RIBOSOME.
SUBCELLULAR LOCATION: CYTOPLASMIC.
SIMILARITY: BELONGS TO THE GTP-BINDING ELONGATION FACTOR FAMILY.
EF-G/EF-2 SUBFAMILY.
|
| | tufA | b3339 | protein chain elongation factor EF-Tu (duplicate of tufB) |
EG11037 |
FUNCTION: THIS PROTEIN PROMOTES THE GTP-DEPENDENT BINDING OF
AMINOACYL-TRNA TO THE A-SITE OF RIBOSOMES DURING PROTEIN
BIOSYNTHESIS.
FUNCTION: MAY PLAY AN IMPORTANT REGULATORY ROLE IN CELL GROWTH AND
IN THE BACTERIAL RESPONSE TO NUTRIENT DEPRIVATION.
SUBUNIT: MONOMER.
SUBCELLULAR LOCATION: CYTOPLASMIC, AND MEMBRANE-ASSOCIATED.
MISCELLANEOUS: THIS CHAIN IS ALSO USED IN BACTERIOPHAGE Q-BETA RNA
POLYMERASE.
MISCELLANEOUS: THE ANTIBIOTIC KIRROMYCIN INHIBITS PROTEIN
BIOSYNTHESIS BY INHIBITING THE RELEASE OF EF-TU FROM THE RIBOSOME.
MISCELLANEOUS: THE ANTIBIOTIC PULVOMYCIN INHIBITS PROTEIN
BIOSYNTHESIS BY DISRUPTING THE ALLOSTERIC CONTROL MECHANISM OF
EF-TU.
MISCELLANEOUS: THE SEQUENCE OF THE TUFB GENE IS SHOWN. TUFA
DIFFERS IN A SINGLE POSITION.
SIMILARITY: BELONGS TO THE GTP-BINDING ELONGATION FACTOR FAMILY.
EF-TU/EF-1A SUBFAMILY.
|
| 1.235617 | - | ychF | b1203 | putative GTP-binding protein |
EG11404 |
SIMILARITY: BELONGS TO THE YCHF FAMILY OF GTP-BINDING PROTEINS.
STRONG, TO H.INFLUENZAE HI0393.
|
| 1.225395 | + | glpD | b3426 | sn-glycerol-3-phosphate dehydrogenase (aerobic) |
EG10394 |
FUNCTION: CONVERSION OF GLYCEROL 3-PHOSPHATE TO DIHYDROXYACETONE.
USES MOLECULAR OXYGEN OR NITRATE AS ELECTRON ACCEPTOR.
CATALYTIC ACTIVITY: SN-GLYCEROL 3-PHOSPHATE + ACCEPTOR =
GLYCERONEPHOSPHATE + REDUCED ACCEPTOR.
COFACTOR: FAD.
SUBCELLULAR LOCATION: CYTOPLASMIC.
MISCELLANEOUS: THERE ARE TWO SN-GLYCEROL-3-PHOSPHATE DEHYDROGENASE
ISOZYMES IN E.COLI: ONE IS AEROBIC, THE OTHER ANAEROBIC.
SIMILARITY: BELONGS TO THE FAD-DEPENDENT GLYCEROL-3-PHOSPHATE
DEHYDROGENASE FAMILY.
|
| 1.165071 | + | yjbE | b4026 | orf, hypothetical protein |
EG11923 |
|
| | yjbF | b4027 | orf, hypothetical protein |
EG11924 |
SUBCELLULAR LOCATION: ATTACHED TO THE MEMBRANE BY A LIPID
ANCHOR (POTENTIAL).
SIMILARITY: STRONG, TO E.COLI YMCC.
|
| | yjbG | b4028 | orf, hypothetical protein |
EG11925 |
SIMILARITY: STRONG, TO E.COLI YMCB.
|
| | yjbH | b4029 | orf, hypothetical protein |
EG11926 |
SUBCELLULAR LOCATION: ATTACHED TO THE MEMBRANE BY A LIPID
ANCHOR (PROBABLE).
SIMILARITY: STRONG, TO E.COLI YMCA.
|
| 1.146322 | - | yraL | b3146 | orf, hypothetical protein |
EG12777 |
SIMILARITY: BELONGS TO THE UPF0011 FAMILY. STRONG, TO H.INFLUENZAE
HI1654.
|
| 1.122139 | + | ansA | b1767 | cytoplasmic L-asparaginase I |
EG10045 |
CATALYTIC ACTIVITY: L-ASPARAGINE + H(2)O = L-ASPARTATE + NH(3).
SUBUNIT: HOMOTETRAMER.
SUBCELLULAR LOCATION: CYTOPLASMIC.
MISCELLANEOUS: KM = 3.5 X 10(-3) M.
MISCELLANEOUS: E.COLI CONTAINS TWO L-ASPARAGINASE ISOENZYMES:
L-ASPARAGINASE I, A LOW-AFFINITY ENZYME LOCATED IN THE CYTOPLASM,
AND L-ASPARAGINASE II, A HIGH-AFFINITY SECRETED ENZYME.
SIMILARITY: BELONGS TO THE ASPARAGINASE 1 FAMILY.
|
| | ydjB | b1768 | orf, hypothetical protein |
EG11135 |
CATALYTIC ACTIVITY: NICOTINAMIDE + H(2)O = NICOTINATE + NH(3).
PATHWAY: PYRIDINE NUCLEOTIDE CYCLE.
SIMILARITY: TO YEAST YGL037C.
|
| 1.099278 | - | chaA | b1216 | sodium-calcium/proton antiporter |
EG11753 |
FUNCTION: ACCORDING TO REF.1 THE NATURAL ACTIVITY OF THIS PROTEIN
IS A CA+/H+ ANTIPORTER, BUT IT CAN ACT AS A WEAK NA+/H+
ANTIPORTER. THE PRESENCE OF A PREFERRED SUBSTRATE AND NORMAL PH
CYTOPLASMIC VALUES MIGHT PREVENT SIGNIFICANT NA+/H+ ANTIPORTER
ACTIVITY.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN.
MISCELLANEOUS: PRONOUNCED PH DEPENDENCE. INHIBITION BY MAGNESIUM.
|
| 1.050718 | + | yjdK | b4128 | orf, hypothetical protein |
EG14342 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
SIMILARITY: STRONG, TO E.COLI YDCX.
|
| 1.024720 | + | yhcS | b3243 | putative transcriptional regulator LYSR-type |
EG12825 |
SIMILARITY: BELONGS TO THE LYSR FAMILY OF TRANSCRIPTIONAL
REGULATORS. STRONG, TO H.INFLUENZAE HI1364.
|