Score |
Strand | Gene name |
Blattner ID |
Description |
EcoCyc link |
SwissProt comment |
| 0.114431 | + | galP | b2943 | galactose-proton symport of transport system |
EG12148 |
FUNCTION: UPTAKE OF GALACTOSE ACROSS THE BOUNDARY MEMBRANE WITH
THE CONCOMITANT EXPORT OF A PROTON (SYMPORT SYSTEM).
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE.
SIMILARITY: BELONGS TO THE SUGAR TRANSPORTER FAMILY.
|
 | | sprT | b2944 | orf, hypothetical protein |
EG12122 |
FUNCTION: INVOLVED IN BOLA GENE EXPRESSION AT THE STATIONARY
PHASE.
SIMILARITY: STRONG, TO H.INFLUENZAE SPRT.
|
| | endA | b2945 | DNA-specific endonuclease I |
EG11336 |
FUNCTION: HAS DOUBLE-STRAND BREAK ACTIVITY.
CATALYTIC ACTIVITY: ENDONUCLEOLYTIC CLEAVAGE TO
5'-PHOSPHODINUCLEOTIDE AND 5'-PHOSPHOOLIGONUCLEOTIDE END-PRODUCTS.
ENZYME REGULATION: IS INHIBITED BY RNA.
SUBCELLULAR LOCATION: PERIPLASMIC.
SIMILARITY: BELONGS TO THE ENDA/NUCM FAMILY OF NUCLEASES.
|
| | yggJ | b2946 | orf, hypothetical protein |
EG12366 |
SIMILARITY: BELONGS TO THE UPF0088 FAMILY. STRONG, TO H.INFLUENZAE
HI0303.
|
| | gshB | b2947 | glutathione synthetase |
EG10419 |
CATALYTIC ACTIVITY: ATP + GAMMA-L-GLUTAMYL-L-CYSTEINE + GLYCINE =
ADP + ORTHOPHOSPHATE + GLUTATHIONE.
ENZYME REGULATION: INHIBITED BY 7,8-DIHYDROFOLATE, METHOTREXATE,
AND TRIMETHOPRIM.
PATHWAY: SECOND STEP IN GLUTATHIONE BIOSYNTHESIS.
SUBUNIT: HOMOTETRAMER.
SIMILARITY: BELONGS TO THE PROKARYOTIC GSH SYNTHASE FAMILY.
|
| | yqgE | b2948 | orf, hypothetical protein |
EG13289 |
SIMILARITY: STRONG, TO H.INFLUENZAE HI0304.
|
| | yqgF | b2949 | orf, hypothetical protein |
EG13290 |
SIMILARITY: BELONGS TO THE UPF0081 FAMILY. STRONG, TO H.INFLUENZAE
HI0305 AND B. APHIDICOLA (SUBSP. ACYRTHOSIPHON PISUM) BU548.
|
| 0.107876 | + | srlA | b2702 | PTS system, glucitol/sorbitol-specific IIC component, one of two |
EG10969 |
FUNCTION: THIS IS A COMPONENT OF THE PHOSPHOENOLPYRUVATE-DEPENDENT
SUGAR PHOSPHOTRANSFERASE SYSTEM (PTS), A MAJOR CARBOHYDRATE ACTIVE
-TRANSPORT SYSTEM. THE IICD DOMAINS CONTAIN THE SUGAR BINDING SITE
AND THE TRANSMEMBRANE CHANNEL; THE IIA DOMAIN CONTAINS THE PRIMARY
PHOSPHORYLATION SITE (THE DONOR IS PHOSPHO-HPR); IIA TRANSFERS ITS
PHOSPHORYL GROUP TO THE IIB DOMAIN WHICH FINALLY TRANSFERS IT TO
THE SUGAR.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE.
SIMILARITY: CONTAINS A PTS EIIC DOMAIN.
|
| | srlE | b2703 | PTS system, glucitol/sorbitol-specific IIB component and second of two IIC components |
EG14373 |
FUNCTION: THIS IS A COMPONENT OF THE PHOSPHOENOLPYRUVATE-DEPENDENT
SUGAR PHOSPHOTRANSFERASE SYSTEM (PTS), A MAJOR CARBOHYDRATE ACTIVE
-TRANSPORT SYSTEM. THE IICD DOMAINS CONTAIN THE SUGAR BINDING SITE
AND THE TRANSMEMBRANE CHANNEL; THE IIA DOMAIN CONTAINS THE PRIMARY
PHOSPHORYLATION SITE (THE DONOR IS PHOSPHO-HPR); IIA TRANSFERS ITS
PHOSPHORYL GROUP TO THE IIB DOMAIN WHICH FINALLY TRANSFERS IT TO
THE SUGAR.
CATALYTIC ACTIVITY: PROTEIN N-PHOSPHOHISTIDINE + SUGAR =
PROTEIN HISTIDINE + SUGAR PHOSPHATE.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE.
SIMILARITY: CONTAINS A PTS EIIB DOMAIN.
SIMILARITY: CONTAINS A PTS EIIC DOMAIN.
|
| | srlB | b2704 | PTS system, glucitol/sorbitol-specific enzyme IIA component |
EG10970 |
FUNCTION: THIS IS A COMPONENT OF THE PHOSPHOENOLPYRUVATE-DEPENDENT
SUGAR PHOSPHOTRANSFERASE SYSTEM (PTS), A MAJOR CARBOHYDRATE ACTIVE
-TRANSPORT SYSTEM. THE IICD DOMAINS CONTAIN THE SUGAR BINDING SITE
AND THE TRANSMEMBRANE CHANNEL; THE IIA DOMAIN CONTAINS THE PRIMARY
PHOSPHORYLATION SITE (THE DONOR IS PHOSPHO-HPR); IIA TRANSFERS ITS
PHOSPHORYL GROUP TO THE IIB DOMAIN WHICH FINALLY TRANSFERS IT TO
THE SUGAR.
CATALYTIC ACTIVITY: PROTEIN N-PHOSPHOHISTIDINE + SUGAR =
PROTEIN HISTIDINE + SUGAR PHOSPHATE.
SUBCELLULAR LOCATION: CYTOPLASMIC.
SIMILARITY: CONTAINS A PTS EIIA DOMAIN.
|
| | srlD | b2705 | glucitol (sorbitol)-6-phosphate dehydrogenase |
EG10971 |
CATALYTIC ACTIVITY: D-SORBITOL-6-PHOSPHATE + NAD(+) = D-FRUCTOSE
6-PHOSPHATE + NADH.
PATHWAY: SORBITOL METABOLIC PATHWAY.
SUBUNIT: HOMOTETRAMER.
SIMILARITY: BELONGS TO THE SHORT-CHAIN DEHYDROGENASES/REDUCTASES
(SDR) FAMILY.
|
| | gutM | b2706 | glucitol operon activator |
EG10972 |
FUNCTION: POSITIVE REGULATOR FOR GLUCITOL OPERON EXPRESSION.
|
| | srlR | b2707 | regulator for gut (srl), glucitol operon |
EG10974 |
INDUCTION: BY GLUCITOL.
SIMILARITY: BELONGS TO THE DEOR FAMILY OF TRANSCRIPTIONAL
REGULATORS.
|
| | gutQ | b2708 | orf, hypothetical protein |
EG10973 |
FUNCTION: NOT KNOWN.
SUBUNIT: HOMODIMER (POSSIBLE).
SIMILARITY: BELONGS TO THE SIS FAMILY. GUTQ/KPSF SUBFAMILY.
SIMILARITY: CONTAINS 2 CBS DOMAINS.
CAUTION: REF.1 SEQUENCE DIFFERS FROM THAT SHOWN DUE TO A
FRAMESHIFT IN POSITION 214.
|
| 0.095891 | + | lexA | b4043 | regulator for SOS(lexA) regulon |
EG10533 |
FUNCTION: REPRESSES A NUMBER OF GENES INVOLVED IN THE RESPONSE TO
DNA DAMAGE (SOS RESPONSE), INCLUDING RECA AND LEXA. HAS BEEN SHOWN
TO BIND TO THE 16 BP PALINDROMIC SEQUENCE 5'-CTGT-AT(4)-ACAG-3'.
IN THE PRESENCE OF SINGLE-STRANDED DNA, RECA INTERACTS WITH LEXA
CAUSING AN AUTOCATALYTIC CLEAVAGE WHICH DISRUPTS THE DNA-BINDING
PART OF LEXA, LEADING TO DEREPRESSION OF THE SOS REGULON AND
EVENTUALLY DNA REPAIR.
CATALYTIC ACTIVITY: HYDROLYSIS OF 84-ALA-|-GLY-85 BOND IN
REPRESSOR LEXA.
SUBUNIT: HOMODIMER.
SIMILARITY: BELONGS TO PEPTIDASE FAMILY S24; ALSO KNOWN AS THE
UMUD/LEXA FAMILY.
|
| | dinF | b4044 | DNA-damage-inducible protein F |
EG11491 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
INDUCTION: BY DNA DAMAGE.
|
| | yjbJ | b4045 | orf, hypothetical protein |
EG11928 |
SIMILARITY: SOME, TO B.SUBTILIS CSBD.
|
| 0.093571 | + | cdsA | b0175 | CDP-diglyceride synthetase |
EG10139 |
CATALYTIC ACTIVITY: CTP + PHOSPHATIDATE = PYROPHOSPHATE +
CDP-DIACYLGLYCEROL.
PATHWAY: PHOSPHOLIPID BIOSYNTHESIS.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE.
SIMILARITY: BELONGS TO THE CDS FAMILY.
|
| | yaeL | b0176 | orf, hypothetical protein |
EG12436 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
SIMILARITY: BELONGS TO THE YAEL/HI0918/HP0258/SLR1821 FAMILY.
SIMILARITY: CONTAINS 1 PDZ/DHR DOMAIN.
|
| | yaeT | b0177 | orf, hypothetical protein |
EG12676 |
SUBCELLULAR LOCATION: OUTER MEMBRANE (POTENTIAL).
SIMILARITY: BELONGS TO THE SURFACE ANTIGEN D15 FAMILY.
|
| | hlpA | b0178 | histone-like protein, located in outer membrane or nucleoid |
EG10455 |
SUBUNIT: HOMOTETRAMER.
SUBCELLULAR LOCATION: EITHER IN THE NUCLEOID (CHROMATIN) OR IN
THE OUTER MEMBRANE.
SIMILARITY: TO OTHER SPECIES OMPH OUTER MEMBRANE PROTEIN.
|
| | lpxD | b0179 | UDP-3-O-(3-hydroxymyristoyl)-glucosamine N-acyltransferase; third step of endotoxin (lipidA) synthesis |
EG10316 |
CATALYTIC ACTIVITY: UDP-3-O-(3-HYDROXYTETRADECANOYL)GLUCOSAMINE
+ (R)-3-HYDROXYTETRADECANOYL-[ACYL-CARRIER PROTEIN] =
UDP-2,3-BIS(3-HYDROXYTETRADECANOYL)GLUCOSAMINE + [ACYL-CARRIER
PROTEIN].
PATHWAY: THIRD STEP IN LIPID A BIOSYNTHESIS.
MISCELLANEOUS: THE MUTANTS FIRA200, FIRA201 AND OMSA CONFER
TEMPERATURE SENSITIVITY. FIRA200 REVERSES THE RIFAMPIN RESISTANCE
OF RPOB MUTANTS.
SIMILARITY: BELONGS TO THE CYSE/LACA/LPXA/NODL FAMILY OF
ACETYLTRANSFERASES. COMPOSED OF MULTIPLE REPEATS OF [LIV]-G-X(4).
CAUTION: WAS ORIGINALLY THOUGHT TO BE INVOLVED IN TRANSCRIPTION.
|
| | fabZ | b0180 | (3R)-hydroxymyristol acyl carrier protein dehydratase |
EG11284 |
FUNCTION: INVOLVED IN SATURATED FATTY ACIDS BIOSYNTHESIS.
SUBUNIT: OLIGOMER.
SUBCELLULAR LOCATION: CYTOPLASMIC.
PTM: THE N-TERMINUS IS BLOCKED.
SIMILARITY: BELONGS TO THE THIOESTER DEHYDRATASE FAMILY.
|
| | lpxA | b0181 | UDP-N-acetylglucosamine acetyltransferase; lipid A biosynthesis |
EG10545 |
FUNCTION: INVOLVED IN THE BIOSYNTHESIS OF LIPID A, A
PHOSPHORYLATED GLYCOLIPID THAT ANCHORS THE LIPOPOLYSACCHARIDE TO
THE OUTER MEMBRANE OF THE CELL.
CATALYTIC ACTIVITY: (R)-3-HYDROXYTETRADECANOYL-[ACYL-CARRIER
PROTEIN] + UDP-N-ACETYLGLUCOSAMINE = [ACYL-CARRIER PROTEIN] +
UDP-3-O-(3-HYDROXYTETRADECANOYL)-N-ACETYLGLUCOSAMINE.
PATHWAY: LIPID A BIOSYNTHESIS; FIRST STEP.
SUBUNIT: HOMOTRIMER.
SUBCELLULAR LOCATION: CYTOPLASMIC.
SIMILARITY: BELONGS TO THE TRANSFERASE HEXAPEPTIDE REPEAT FAMILY.
LPXA SUBFAMILY.
|
| | lpxB | b0182 | tetraacyldisaccharide-1-P; lipid A biosynthesis, penultimate step |
EG10546 |
FUNCTION: CONDENSATION OF UDP-2,3-DIACYLGLUCOSAMINE AND
2,3-DIACYLGLUCOSAMINE-1-PHOSPHATE TO FORM LIPID A DISACCHARIDE,
A PRECURSOR OF LIPID A, A PHOSPHORYLATED GLYCOLIPID THAT ANCHORS
THE LIPOPOLYSACCHARIDE TO THE OUTER MEMBRANE OF THE CELL.
CATALYTIC ACTIVITY: UDP-2,3-BIS(3-HYDROXYTETRADECANOYL)GLUCOSAMINE
+ 2,3-BIS(3-HYDROXYTETRADECANOYL)-BETA-D-GLUCOSAMINYL 1-PHOSPHATE
= UDP + 2,3-BIS(3-HYDROXYTETRADECANOYL)-D-GLUCOSAMINYL-1,6-BETA-
D-2,3-BIS(3-HYDROXYTETRADECANOYL)-BETA-D-GLUCOSAMINYL 1-PHOSPHATE.
PATHWAY: LIPID A BIOSYNTHESIS.
SIMILARITY: BELONGS TO THE LPXB FAMILY.
|
| | rnhB | b0183 | RNAse HII, degrades RNA of DNA-RNA hybrids |
EG10861 |
FUNCTION: DEGRADES THE RIBONUCLEOTIDE MOIETY ON RNA-DNA HYBRID
MOLECULES.
CATALYTIC ACTIVITY: ENDONUCLEOLYTIC CLEAVAGE TO 5'-PHOSPHO-
MONOESTER.
COFACTOR: REQUIRES MANGANESE FOR ACTIVITY.
SUBCELLULAR LOCATION: CYTOPLASMIC (POTENTIAL).
SIMILARITY: BELONGS TO THE RNASE HII FAMILY.
|
| | dnaE | b0184 | DNA polymerase III, alpha subunit |
EG10238 |
FUNCTION: DNA POLYMERASE III IS A COMPLEX, MULTICHAIN ENZYME
RESPONSIBLE FOR MOST OF THE REPLICATIVE SYNTHESIS IN BACTERIA.
THIS DNA POLYMERASE ALSO EXHIBITS 3' TO 5' EXONUCLEASE ACTIVITY.
THE ALPHA CHAIN IS THE DNA POLYMERASE.
CATALYTIC ACTIVITY: N DEOXYNUCLEOSIDE TRIPHOSPHATE =
N PYROPHOSPHATE + DNA(N).
SUBUNIT: CONTAINS A CORE (COMPOSED OF ALPHA, EPSILON, AND THETA
CHAINS) THAT ASSOCIATES WITH A TAU SUBUNIT WHICH ALLOW THE CORE
DIMERIZATION TO FORM THE POLIII' COMPLEX. POLIII' ASSOCIATES WITH
THE GAMMA COMPLEX (COMPOSED OF CHAINS GAMMA, DELTA, DELTA', PSI,
AND CHI) AND WITH THE BETA CHAIN. THE FINAL COMPOSITION OF THE
COMPLEX IS: (ALPHA,EPSILON,THETA)[2]-TAU[2]-(GAMMA,DELTA,DELTA',
PSI,CHI)[2]-BETA[4].
SUBCELLULAR LOCATION: CYTOPLASMIC.
SIMILARITY: BELONGS TO DNA POLYMERASE TYPE-C FAMILY. DNAE
SUBFAMILY.
|
| | accA | b0185 | acetylCoA carboxylase, carboxytransferase component, alpha subunit |
EG11647 |
FUNCTION: THIS PROTEIN IS A COMPONENT OF THE ACETYL COENZYME A
CARBOXYLASE COMPLEX; FIRST, BIOTIN CARBOXYLASE CATALYZES THE
CARBOXYLATION OF THE CARRIER PROTEIN AND THEN THE TRANSCARBOXYLASE
TRANSFERS THE CARBOXYL GROUP TO FORM MALONYL-COA.
CATALYTIC ACTIVITY: CARBOXYBIOTIN CARBOXYL CARRIER PROTEIN +
ACETYL-COA = BIOTIN CARBOXYL CARRIER PROTEIN + MALONYL-COA.
PATHWAY: FIRST STEP IN LONG-CHAIN FATTY ACID SYNTHESIS.
SUBUNIT: ACETYL-COA CARBOXYLASE IS AN HETEROHEXAMER OF BIOTIN
CARBOXYL CARRIER PROTEIN, BIOTIN CARBOXYLASE AND THE TWO SUBUNITS
OF CARBOXYL TRANSFERASE IN A 2:2 COMPLEX.
SIMILARITY: TO THE C-TERMINUS OF MAMMALIAN PROPIONYL-COA
CARBOXYLASE BETA CHAIN.
|
| | ldcC | b0186 | lysine decarboxylase 2, constitutive |
EG13219 |
FUNCTION: LDC IS CONSTITUTIVELY BUT WEAKLY EXPRESSED UNDER VARIOUS
CONDITIONS. OPTIMUM ACTIVITY IS ACHIEVED BETWEEN PH 6.2 TO 8.0.
CATALYTIC ACTIVITY: L-LYSINE = CADAVERINE + CO(2).
COFACTOR: PYRIDOXAL PHOSPHATE.
SUBUNIT: HOMODECAMER.
SIMILARITY: BELONGS TO FAMILY 1 OF ORNITHINE, LYSINE, AND ARGININE
DECARBOXYLASES.
|
| | yaeR | b0187 | orf, hypothetical protein |
EG13224 |
SIMILARITY: STRONG, TO B.SUBTILIS YWKD.
|
| | mesJ | b0188 | cell cycle protein |
EG13220 |
SIMILARITY: BELONGS TO THE UPF0072 (MESJ/YCF62) FAMILY.
|
| 0.067499 | + | b2834 | b2834 | orf, hypothetical protein |
EG13093 |
SIMILARITY: BELONGS TO THE ALDO/KETO REDUCTASE 2 FAMILY.
|
| 0.064910 | + | xylR | b3569 | putative regulator of xyl operon |
EG20253 |
FUNCTION: REGULATORY PROTEIN FOR THE XYLBAFGHR OPERON.
SIMILARITY: BELONGS TO THE ARAC/XYLS FAMILY OF TRANSCRIPTIONAL
REGULATORS.
|
| 0.063914 | + | gst | b1635 | glutathionine S-transferase |
EG12613 |
FUNCTION: CONJUGATION OF REDUCED GLUTATHIONE TO A WIDE NUMBER OF
EXOGENOUS AND ENDOGENOUS HYDROPHOBIC ELECTROPHILES. OPTIMA OF PH
AND TEMPERATURE ARE 7.5 AND 35 DEGREES CELSIUS.
CATALYTIC ACTIVITY: RX + GLUTATHIONE = HX + R-S-GLUTATHIONE.
SUBUNIT: HOMODIMER.
SUBCELLULAR LOCATION: CYTOPLASMIC.
SIMILARITY: BELONGS TO THE GST SUPERFAMILY. BETA SUBFAMILY.
|
| 0.063760 | + | yeaP | b1794 | orf, hypothetical protein |
EG13502 |
SIMILARITY: BELONGS TO THE YEGE/YHDA/YHJK/YJCC FAMILY.
|
| 0.063396 | + | proB | b0242 | gamma-glutamate kinase |
EG10768 |
CATALYTIC ACTIVITY: ATP + L-GLUTAMATE = ADP + L-GLUTAMATE
5-PHOSPHATE (PRODUCT RAPIDLY CYCLIZES TO 5-OXOPROLINE AND
ORTHOPHOSPHATE).
PATHWAY: FIRST STEP IN PROLINE BIOSYNTHESIS PATHWAY.
SUBCELLULAR LOCATION: CYTOPLASMIC.
SIMILARITY: BELONGS TO THE GLUTAMATE 5-KINASE FAMILY.
|
| | proA | b0243 | gamma-glutamylphosphate reductase |
EG10767 |
FUNCTION: CATALYZES THE NADPH DEPENDENT REDUCTION OF L-GAMMA-
GLUTAMYL 5-PHOSPHATE INTO L-GLUTAMATE 5-SEMIALDEHYDE AND
PHOSPHATE. THE PRODUCT SPONTANEOUSLY UNDERGOES CYCLIZATION TO FORM
1-PYRROLINE-5-CARBOXYLATE.
CATALYTIC ACTIVITY: L-GLUTAMATE 5-SEMIALDEHYDE + ORTHOPHOSPHATE +
NADP(+) = L-GAMMA-GLUTAMYL 5-PHOSPHATE + NADPH.
PATHWAY: PROLINE BIOSYNTHESIS PATHWAY; SECOND STEP.
SUBCELLULAR LOCATION: CYTOPLASMIC.
SIMILARITY: BELONGS TO THE GAMMA-GLUTAMYL PHOSPHATE REDUCTASE
FAMILY.
|
| 0.062889 | + | yagE | b0268 | putative lyase/synthase |
EG13344 |
SIMILARITY: BELONGS TO THE DHDPS FAMILY. STRONG, TO E.COLI YJHH.
|
| | yagF | b0269 | putative dehydratase |
EG13345 |
SIMILARITY: BELONGS TO THE ILVD / EDD FAMILY. STRONG, TO E.COLI
YJHG.
|
| 0.061318 | + | oppB | b1244 | oligopeptide transport permease protein |
EG10675 |
FUNCTION: PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM
FOR OLIGOPEPTIDES; PROBABLY RESPONSIBLE FOR THE TRANSLOCATION OF
THE SUBSTRATE ACROSS THE MEMBRANE.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE.
SIMILARITY: WITH INTEGRAL MEMBRANE COMPONENTS OF OTHER BINDING-
PROTEIN-DEPENDENT TRANSPORT SYSTEMS. BELONGS TO THE OPPBC
SUBFAMILY.
|
| | oppC | b1245 | homolog of Salmonella oligopeptide transport permease protein |
EG10676 |
FUNCTION: PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM
FOR OLIGOPEPTIDES; PROBABLY RESPONSIBLE FOR THE TRANSLOCATION OF
THE SUBSTRATE ACROSS THE MEMBRANE.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE.
SIMILARITY: WITH INTEGRAL MEMBRANE COMPONENTS OF OTHER BINDING-
PROTEIN-DEPENDENT TRANSPORT SYSTEMS. BELONGS TO THE OPPBC
SUBFAMILY.
|
| | oppD | b1246 | homolog of Salmonella ATP-binding protein of oligopeptide ABC transport system |
EG10677 |
FUNCTION: PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM
FOR OLIGOPEPTIDES. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE
TRANSPORT SYSTEM.
SUBCELLULAR LOCATION: INNER MEMBRANE-ASSOCIATED.
SIMILARITY: BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY
(ABC TRANSPORTERS). OPPD AND OPPF SHOW AN EXTENSIVE HOMOLOGY WITH
EACH OTHER.
|
| | oppF | b1247 | homolog of Salmonella ATP-binding protein of oligopeptide ABC transport system |
EG10678 |
FUNCTION: PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM
FOR OLIGOPEPTIDES. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE
TRANSPORT SYSTEM.
SUBCELLULAR LOCATION: INNER MEMBRANE-ASSOCIATED.
SIMILARITY: BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY
(ABC TRANSPORTERS). OPPD AND OPPF SHOW AN EXTENSIVE HOMOLOGY WITH
EACH OTHER.
|
| 0.060761 | + | yeaU | b1800 | putative tartrate dehydrogenase |
EG13507 |
CATALYTIC ACTIVITY: TARTRATE + NAD(+) = OXALOGLYCOLATE + NADH.
SUBCELLULAR LOCATION: CYTOPLASMIC (BY SIMILARITY).
SIMILARITY: BELONGS TO THE ISOCITRATE AND ISOPROPYLMALATE
DEHYDROGENASES FAMILY.
|
| 0.060677 | + | yicH | b3655 | orf, hypothetical protein |
EG11684 |
|
| 0.060389 | + | yjiD | b4326 | orf, hypothetical protein |
EG12565 |
|
| 0.060126 | + | ribH | b0415 | riboflavin synthase, beta chain |
EG11322 |
FUNCTION: RIBOFLAVIN SYNTHASE IS A BIFUNCTIONAL ENZYME COMPLEX
CATALYZING THE FORMATION OF RIBOFLAVIN FROM 5-AMINO-6-(1'-D)-
RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE AND L-3,4-DIHYDROHY-2-
BUTANONE-4-PHOSPHATE VIA 6,7-DIMETHYL-8-LUMAZINE. THE BETA
SUBUNIT CATALYZES THE CONDENSATION OF 5-AMINO-6-(1'-D)-RIBITYL-
AMINO-2,4(1H,3H)-PYRIMIDINEDIONE WITH L-3,4-DIHYDROHY-2-BUTANONE-
4-PHOSPHATE YIELDING 6,7-DIMETHYL-8-LUMAZINE.
CATALYTIC ACTIVITY: 2 6,7-DIMETHYL-8-(1-D-RIBITYL)LUMAZINE =
RIBOFLAVIN + 4-(1-D-RIBITYLAMINO)-5-AMINO-2,6-DIHYDROXYPYRIMIDINE.
COFACTOR: FLAVOPROTEIN.
PATHWAY: FINAL STEP OF RIBOFLAVIN SYNTHESIS.
SUBUNIT: OLIGOMER THAT CONSIST OF 3 ALPHA SUBUNITS AND 60 BETA
SUBUNITS (BY SIMILARITY).
SIMILARITY: BELONGS TO THE DMRL SYNTHASE FAMILY.
|
| | nusB | b0416 | transcription termination; L factor |
EG10666 |
FUNCTION: THIS IS ONE OF THE PROTEINS ESSENTIAL FOR THE FORMATION
OF THE RNA POLYMERASE ANTITERMINATION COMPLEX IN THE PRESENCE OF
LAMBDA PHAGE N PROTEIN. HOWEVER, IT IS INVOLVED IN THE
TRANSCRIPTION TERMINATION PROCESS AT CERTAIN SITES DURING NORMAL
BACTERIAL GROWTH. BINDS TO THE BOXA RNA MOTIF.
SUBUNIT: MONOMER.
SIMILARITY: BELONGS TO THE NUSB FAMILY.
|
| | thiL | b0417 | thiamin-monophosphate kinase |
EG20227 |
CATALYTIC ACTIVITY: ATP + THIAMINE PHOSPHATE = ADP + THIAMINE
DIPHOSPHATE.
PATHWAY: THIAMINE BIOSYNTHESIS.
SIMILARITY: BELONGS TO THE THIAMINE-MONOPHOSPHATE KINASE FAMILY.
|
| | pgpA | b0418 | phosphatidylglycerophosphatase |
EG10704 |
FUNCTION: ONE OF THE THREE PHOSPHOLIPID PHOSPHATASES, SPECIFICALLY
HYDROLYZES PHOSPHATIDYLGLYCEROPHOSPHATE.
CATALYTIC ACTIVITY: PHOSPHATIDYLGLYCEROPHOSPHATE + H(2)O =
PHOSPHATIDYLGLYCEROL + ORTHOPHOSPHATE.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE.
CAUTION: REF.1 SEQUENCE DIFFERS FROM THAT SHOWN BY A FRAMESHIFT
IN POSITION 42. IN ADDITION THE AUTHOR OF REF.1 HAS TRANSLATED
THE WRONG DNA STRAND THUS PRODUCING AN ORF WHICH HAS NOTHING TO
DO WITH THE ONE SHOWN HERE.
|
| 0.059702 | + | dadA | b1189 | D-amino acid dehydrogenase subunit |
EG11407 |
FUNCTION: OXIDATIVE DEAMINATION OF D-AMINO ACIDS.
CATALYTIC ACTIVITY: A D-AMINO ACID + H(2)O + ACCEPTOR = A 2-OXO
ACID + NH(3) + REDUCED ACCEPTOR.
COFACTOR: FAD AND NONHEME IRON.
PATHWAY: ALANINE CATABOLISM.
SUBUNIT: HETERODIMER OF A SMALL AND A LARGE SUBUNIT.
SUBCELLULAR LOCATION: INNER MEMBRANE-BOUND.
INDUCTION: BY ALANINE.
SIMILARITY: BELONGS TO THE DADA FAMILY OF OXIDOREDUCTASES.
|
| | dadX | b1190 | alanine racemase 2, catabolic |
EG11408 |
CATALYTIC ACTIVITY: L-ALANINE = D-ALANINE.
COFACTOR: PYRIDOXAL PHOSPHATE.
SUBUNIT: MONOMER.
INDUCTION: BY ALANINE.
SIMILARITY: BELONGS TO THE ALANINE RACEMASE FAMILY.
|
| 0.058478 | + | yqcE | b2775 | putative transport protein |
EG13174 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
SIMILARITY: TO E.COLI YIHN.
|
| | ygcE | b2776 | putative kinase |
EG13033 |
SIMILARITY: BELONGS TO THE FUCOKINASE / GLUCONOKINASE /
GLYCEROKINASE / XYLULOKINASE FAMILY.
|
| 0.057566 | + | yfcC | b2298 | putative S-transferase |
EG12607 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
SIMILARITY: TO H.INFLUENZAE HI0594.
SIMILARITY: TO B.SUBTILIS YCGA.
|
| 0.057178 | + | yggJ | b2946 | orf, hypothetical protein |
EG12366 |
SIMILARITY: BELONGS TO THE UPF0088 FAMILY. STRONG, TO H.INFLUENZAE
HI0303.
|
| | gshB | b2947 | glutathione synthetase |
EG10419 |
CATALYTIC ACTIVITY: ATP + GAMMA-L-GLUTAMYL-L-CYSTEINE + GLYCINE =
ADP + ORTHOPHOSPHATE + GLUTATHIONE.
ENZYME REGULATION: INHIBITED BY 7,8-DIHYDROFOLATE, METHOTREXATE,
AND TRIMETHOPRIM.
PATHWAY: SECOND STEP IN GLUTATHIONE BIOSYNTHESIS.
SUBUNIT: HOMOTETRAMER.
SIMILARITY: BELONGS TO THE PROKARYOTIC GSH SYNTHASE FAMILY.
|
| | yqgE | b2948 | orf, hypothetical protein |
EG13289 |
SIMILARITY: STRONG, TO H.INFLUENZAE HI0304.
|
| | yqgF | b2949 | orf, hypothetical protein |
EG13290 |
SIMILARITY: BELONGS TO THE UPF0081 FAMILY. STRONG, TO H.INFLUENZAE
HI0305 AND B. APHIDICOLA (SUBSP. ACYRTHOSIPHON PISUM) BU548.
|
| 0.056430 | + | yigM | b3827 | orf, hypothetical protein |
EG11471 |
CAUTION: REF.1 SEQUENCE DIFFERS FROM THAT SHOWN FROM POSITION 278
ONWARD AND IS LONGER (299 AA) DUE TO A FRAMESHIFT.
|
| 0.055407 | + | yhdJ | b3262 | putative methyltransferase |
EG11498 |
CATALYTIC ACTIVITY: S-ADENOSYL-L-METHIONINE + DNA ADENINE =
S-ADENOSYL-L-HOMOCYSTEINE + DNA 6-METHYLAMINOPURINE.
SIMILARITY: BELONGS TO THE N-6 ADENINE-SPECIFIC DNA METHYLASE
FAMILY.
|
| | yhdU | b3263 | orf, hypothetical protein |
EG12832 |
|
| 0.054607 | + | ybcN | b0547 | orf, hypothetical protein |
EG13630 |
SIMILARITY: STRONG, TO EQUIVALENT PROTEIN IN PHAGE 82.
|
| | ninE | b0548 | similar to phage 82 and lambda proteins |
EG14286 |
SIMILARITY: BELONGS TO THE NINE FAMILY.
|
| | ybcO | b0549 | orf, hypothetical protein |
EG13631 |
|
| | rus | b0550 | endodeoxyribonuclease RUS (Holliday junction resolvase) |
EG14354 |
SIMILARITY: STRONG, TO EQUIVALENT PROTEIN IN PHAGE 82.
|
| 0.054384 | + | dld | b2133 | D-lactate dehydrogenase, FAD protein, NADH independent |
EG10231 |
FUNCTION: FIRST COMPONENT OF THE MEMBRANE-BOUND D-LACTATE OXIDASE,
WHICH IS BELIEVED TO PLAY AN IMPORTANT ROLE IN THE ENERGIZATION OF
THE ACTIVE TRANSPORT OF A VARIETY OF SUGARS AND AMINO ACIDS.
CATALYTIC ACTIVITY: D-LACTATE + NAD(+) = PYRUVATE + NADH.
COFACTOR: FAD.
ENZYME REGULATION: REQUIRES PHOSPHOLIPID FOR MAXIMAL ACTIVITY.
SUBCELLULAR LOCATION: MEMBRANE BOUND LOCATED AT THE INNER FACE OF
THE CYTOPLASMIC MEMBRANE.
|
| 0.054041 | + | nikA | b3476 | periplasmic binding protein for nickel |
EG12075 |
FUNCTION: INVOLVED IN A NICKEL TRANSPORT SYSTEM, PROBABLY
REPRESENTS THE NICKEL BINDER.
SUBCELLULAR LOCATION: PERIPLASMIC (PROBABLE).
SIMILARITY: BELONGS TO THE BACTERIAL EXTRACELLULAR SOLUTE-BINDING
PROTEIN FAMILY 5.
|
| | nikB | b3477 | transport of nickel, membrane protein |
EG12076 |
FUNCTION: INVOLVED IN A NICKEL TRANSPORT SYSTEM, PROBABLY
TRANSLOCATES NICKEL THROUGH THE BACTERIAL INNER MEMBRANE.
SUBUNIT: PROBABLY FORMS AN HETERODIMERIC PORE WITH NIKC.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE.
(POTENTIAL).
SIMILARITY: WITH INTEGRAL MEMBRANE COMPONENTS OF OTHER BINDING-
PROTEIN-DEPENDENT TRANSPORT SYSTEMS. BELONGS TO THE OPPBC
SUBFAMILY.
|
| | nikC | b3478 | transport of nickel, membrane protein |
EG12077 |
FUNCTION: INVOLVED IN A NICKEL TRANSPORT SYSTEM, PROBABLY
TRANSLOCATES NICKEL THROUGH THE BACTERIAL INNER MEMBRANE.
SUBUNIT: PROBABLY FORMS AN HETERODIMERIC PORE WITH NIKB.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE.
(POTENTIAL).
SIMILARITY: WITH INTEGRAL MEMBRANE COMPONENTS OF OTHER BINDING-
PROTEIN-DEPENDENT TRANSPORT SYSTEMS. BELONGS TO THE OPPBC
SUBFAMILY.
|
| | nikD | b3479 | ATP-binding protein of nickel transport system |
EG12078 |
FUNCTION: PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM
FOR NICKEL. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE
TRANSPORT SYSTEM.
SUBCELLULAR LOCATION: INNER MEMBRANE-ASSOCIATED (POTENTIAL).
SIMILARITY: BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY
(ABC TRANSPORTERS).
|
| | nikE | b3480 | ATP-binding protein of nickel transport system |
EG12079 |
FUNCTION: PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM
FOR NICKEL. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE
TRANSPORT SYSTEM.
SUBCELLULAR LOCATION: INNER MEMBRANE-ASSOCIATED (POTENTIAL).
SIMILARITY: BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY
(ABC TRANSPORTERS).
|
| | yhhG | b3481 | orf, hypothetical protein |
EG11519 |
SIMILARITY: TO M.JANNASCHII MJ0080, MJ0549 AND MJ0767.
|
| 0.053412 | + | yieH | b3715 | putative phosphatase |
EG11725 |
SIMILARITY: BELONGS TO THE CBBY/CBBZ/GPH/YIEH FAMILY.
|
| | yieI | b3716 | orf, hypothetical protein |
EG11726 |
|
| | yieJ | b3717 | orf, hypothetical protein |
EG11727 |
SIMILARITY: TO M.TUBERCULOSIS RV2295.
|
| 0.053165 | + | b1445 | b1445 | orf, hypothetical protein |
EG13767 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
SIMILARITY: STRONG, TO E.COLI YJDO.
|
| | b1446 | b1446 | orf, hypothetical protein |
EG13768 |
|
| 0.052485 | + | recN | b2616 | protein used in recombination and DNA repair |
EG10831 |
FUNCTION: MAY BE INVOLVED IN RECOMBINATIONAL REPAIR OF DAMAGED
DNA.
SIMILARITY: BELONGS TO THE RECN FAMILY.
|
| 0.052000 | + | yaaF | b0030 | orf, hypothetical protein |
EG11082 |
SIMILARITY: BELONGS TO THE IUNH FAMILY.
|
| 0.051070 | + | yhfK | b3358 | orf, hypothetical protein |
EG12906 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
SIMILARITY: BELONGS TO THE YCCS/YHFK FAMILY.
|
| 0.050985 | + | yhdT | b3257 | orf, hypothetical protein |
EG12831 |
SIMILARITY: STRONG, TO H.INFLUENZAE HI0974B.
CAUTION: REF.3 SEQUENCE DIFFERS FROM THAT SHOWN DUE TO A
FRAMESHIFT.
|
| | panF | b3258 | sodium/pantothenate symporter |
EG10685 |
FUNCTION: CATALYZES THE SODIUM-DEPENDENT UPTAKE OF EXTRACELLULAR
PANTOTHENATE.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE.
SIMILARITY: BELONGS TO THE SODIUM:SOLUTE SYMPORTER FAMILY (SSF).
|
| | prmA | b3259 | methylase for 50S ribosomal subunit protein L11 |
EG11497 |
FUNCTION: METHYLATES RIBOSOMAL PROTEIN L11.
SIMILARITY: TO OTHER METHYLTRANSFERASES.
|
| 0.050677 | + | yjfP | b4190 | orf, hypothetical protein |
EG12490 |
|
| 0.050522 | + | ydfE | b1577 | orf, hypothetical protein |
EG11304 |
CAUTION: THIS IS A CONCEPTUAL TRANSLATION; THE ORIGINAL PROTEIN IS
TRUNCATED BY AN IS2 ELEMENT WHICH IS INSERTED RIGHT AFTER RESIDUE
255. WHAT WAS THE ORIGINAL C-TERMINAL OF THIS PROTEIN IS NOT
KNOWN.
|
| | b1578 | b1578 | orf, hypothetical protein |
|
|
| | b1579 | b1579 | putative transposase |
EG13188 |
FUNCTION: INTEGRASE IS NECESSARY FOR INTEGRATION OF THE PHAGE INTO
THE HOST GENOME BY SITE-SPECIFIC RECOMBINATION. IN CONJUNCTION
WITH EXCISIONASE, INTEGRASE IS ALSO NECESSARY FOR EXCISION OF THE
PROPHAGE FROM THE HOST GENOME (BY SIMILARITY).
SIMILARITY: BELONGS TO THE "PHAGE" INTEGRASE FAMILY.
CAUTION: THIS IS A CONCEPTUAL TRANSLATION; THIS PROTEIN IS
INTERRUPTED BY AN IS2 ELEMENT.
|
| 0.050100 | + | pphB | b2734 | protein phosphatase 2 |
EG13102 |
FUNCTION: HAS BEEN SHOWN, IN VITRO, TO ACT ON SER, THR AND
TYR-PHOSPHORYLATED SUBSTRATES.
CATALYTIC ACTIVITY: A PHOSPHOPROTEIN + H(2)O = A PROTEIN +
ORTHOPHOSPHATE.
SIMILARITY: BELONGS TO THE PPP FAMILY OF PHOSPHATASES.
|
| 0.049799 | + | fhlA | b2731 | formate hydrogen-lyase transcriptional activator for fdhF, hyc and hyp operons |
EG10301 |
FUNCTION: REQUIRED FOR INDUCTION OF EXPRESSION OF THE FORMATE
DEHYDROGENASE H AND HYDROGENASE-3 STRUCTURAL GENES.
SIMILARITY: THE CENTRAL REGION CONTAINS A SIGMA-54 FACTOR
INTERACTION ATP-BINDING DOMAIN.
|
| 0.049082 | + | gabP | b2663 | transport permease protein of gamma-aminobutyrate |
EG11330 |
FUNCTION: TRANSPORTER FOR GABA.
PATHWAY: 4-AMINOBUTYRATE (GABA) DEGRADATION PATHWAY.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE.
SIMILARITY: BELONGS TO THE AMINO ACID PERMEASE FAMILY.
|
| | ygaE | b2664 | putative transcriptional regulator |
EG12386 |
SIMILARITY: BELONGS TO THE GNTR FAMILY OF TRANSCRIPTIONAL
REGULATORS. STRONG, TO P.CEPACIA HYPOTHETICAL PROTEIN IN BPHA
5'REGION (AC P37335).
|