Score |
Strand | Gene name |
Blattner ID |
Description |
EcoCyc link |
SwissProt comment |
| 3.365770 | - | gltX | b2400 | glutamate tRNA synthetase, catalytic subunit |
EG10407 |
CATALYTIC ACTIVITY: ATP + L-GLUTAMATE + TRNA(GLU) = AMP +
PYROPHOSPHATE + L-GLUTAMYL-TRNA(GLU).
SUBUNIT: MONOMER.
SUBCELLULAR LOCATION: CYTOPLASMIC.
MISCELLANEOUS: THIS IS THE SMALLEST AMINOACYL-TRNA SYNTHETASE OF
E.COLI; IT DOES NOT BIND GLUTAMATE IN THE ABSENCE OF COGNATE TRNA,
WHICH IS THEREFORE REQUIRED FOR ACTIVATION OF THE AMINO ACID
SUBSTRATE.
SIMILARITY: BELONGS TO CLASS-I AMINOACYL-TRNA SYNTHETASE FAMILY.
|
| 2.137817 | + | yafB | b0207 | putative aldose reductase (EC 1.1.1.21) |
EG11648 |
SIMILARITY: BELONGS TO THE ALDO/KETO REDUCTASE FAMILY.
|
| 1.619046 | + | yafT | b0217 | putative aminopeptidase |
EG13332 |
SUBCELLULAR LOCATION: ATTACHED TO THE MEMBRANE BY A LIPID
ANCHOR (PROBABLE).
|
| 1.429548 | + | yhgF | b3407 | orf, hypothetical protein |
EG12932 |
SIMILARITY: STRONG, TO H.INFLUENZAE HI0568.
SIMILARITY: CONTAINS 1 'S1 MOTIF' DOMAIN.
|
| 0.416699 | + | b1030 | b1030 | orf, hypothetical protein |
 |
|
| | ycdV | b1031 | putative ribosomal protein |
|
|
| 0.379246 | + | b1667 | b1667 | orf, hypothetical protein |
EG13952 |
|
| | b1668 | b1668 | orf, hypothetical protein |
EG13953 |
|
| 0.369449 | + | aidB | b4187 | putative acyl coenzyme A dehydrogenase |
EG11811 |
INDUCTION: BY ALKYLATING AGENTS.
SIMILARITY: BELONGS TO THE ACYL-COA DEHYDROGENASES FAMILY.
|
| 0.365916 | + | tolA | b0739 | membrane spanning protein, required for outer membrane integrity |
EG11007 |
FUNCTION: INVOLVED IN THE TONB-INDEPENDENT UPTAKE OF GROUP A
COLICINS (COLICINS A, E1, E2, E3, AND K). NECESSARY FOR THE
COLICINS TO REACH THEIR RESPECTIVE TARGETS AFTER INITIAL
BINDING TO THE BACTERIA. ALSO INVOLVED IN THE TRANSLOCATION
OF BACTERIOPHAGE DNA.
SUBUNIT: INTERACTS, VIA DOMAIN II, WITH PORINS OMPC, OMPC, PHOE
AND LAMB.
SUBCELLULAR LOCATION: TYPE II MEMBRANE PROTEIN. INNER MEMBRANE.
|
| | tolB | b0740 | periplasmic protein involved in the tonb-independent uptake of group A colicins |
EG11008 |
FUNCTION: INVOLVED IN THE TONB-INDEPENDENT UPTAKE OF GROUP A
COLICINS (COLICINS A, E1, E2, E3, AND K). NECESSARY FOR THE
COLICINS TO REACH THEIR RESPECTIVE TARGETS AFTER INITIAL
BINDING TO THE BACTERIA.
SUBCELLULAR LOCATION: PERIPLASMIC.
SIMILARITY: BELONGS TO THE TOLB FAMILY.
|
| | pal | b0741 | peptidoglycan-associated lipoprotein |
EG10684 |
FUNCTION: VERY STRONGLY ASSOCIATED WITH THE PEPTIDOGLYCAN.
SUBCELLULAR LOCATION: ATTACHED TO THE OUTER MEMBRANE BY A LIPID
ANCHOR.
SIMILARITY: TO OTHER PAL PROTEINS.
|
| | ybgF | b0742 | orf, hypothetical protein |
EG12854 |
SIMILARITY: TO P.PUTIDA HYPOTHETICAL 28.7 KDA PROTEIN IN PAL
5'REGION (AC P43037).
CAUTION: REF.1 SEQUENCE DIFFERS FROM THAT SHOWN DUE TO FRAMESHIFTS
IN POSITIONS 34 AND 41.
|
| 0.265148 | + | ydiS | b1699 | flavoprotein; probably electron transport |
EG13978 |
FUNCTION: PROBABLY ACCEPTS ELECTRONS FROM YDIQ/YDIR AND REDUCES
A QUINONE.
COFACTOR: FAD (POTENTIAL).
SIMILARITY: BELONGS TO THE ETF-QO / FIXC FAMILY.
|
| | ydiT | b1700 | orf, hypothetical protein |
EG13979 |
FUNCTION: COULD BE A 3FE-4S CLUSTER-CONTAINING PROTEIN. PROBABLY
PARTICIPATES IN A REDOX PROCESS WITH YDIQ, YDIR AND YDIS.
SIMILARITY: TO VARIOUS BACTERIAL FERREDOXINS, STRONGEST TO FIXX
FROM NITROGEN FIXING BACTERIA.
|
| | ydiD | b1701 | putative ligase/synthetase |
EG12357 |
SIMILARITY: BELONGS TO THE ATP-DEPENDENT AMP-BINDING ENZYME
FAMILY. STRONG, TO 2,3-DIHYDROXYBENZOATE-AMP LIGASE.
CAUTION: REF.3 SEQUENCE DIFFERS FROM THAT SHOWN DUE TO
FRAMESHIFTS.
|
| 0.176510 | - | b1664 | b1664 | possible enzyme |
|
|
| 0.162885 | + | yafA | b0239 | orf, hypothetical protein |
EG11091 |
|
| | crl | b0240 | transcriptional regulator of cryptic csgA gene for curli surface fibers |
EG11092 |
FUNCTION: BEHAVES AS A TRANSCRIPTIONAL MODULATOR ACTIVATING THE
GENE FOR CURLIN AND PROBABLY OTHER GENES INVOLVED IN CURLI
FORMATION.
SUBCELLULAR LOCATION: CYTOPLASMIC.
|
| 0.139770 | + | b0703 | b0703 | orf, hypothetical protein |
EG13661 |
SIMILARITY: BELONGS TO THE RHS FAMILY.
|
| | ybfC | b0704 | orf, hypothetical protein |
EG11523 |
|
| 0.129730 | + | cdsA | b0175 | CDP-diglyceride synthetase |
EG10139 |
CATALYTIC ACTIVITY: CTP + PHOSPHATIDATE = PYROPHOSPHATE +
CDP-DIACYLGLYCEROL.
PATHWAY: PHOSPHOLIPID BIOSYNTHESIS.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE.
SIMILARITY: BELONGS TO THE CDS FAMILY.
|
| | yaeL | b0176 | orf, hypothetical protein |
EG12436 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
SIMILARITY: BELONGS TO THE YAEL/HI0918/HP0258/SLR1821 FAMILY.
SIMILARITY: CONTAINS 1 PDZ/DHR DOMAIN.
|
| | yaeT | b0177 | orf, hypothetical protein |
EG12676 |
SUBCELLULAR LOCATION: OUTER MEMBRANE (POTENTIAL).
SIMILARITY: BELONGS TO THE SURFACE ANTIGEN D15 FAMILY.
|
| | hlpA | b0178 | histone-like protein, located in outer membrane or nucleoid |
EG10455 |
SUBUNIT: HOMOTETRAMER.
SUBCELLULAR LOCATION: EITHER IN THE NUCLEOID (CHROMATIN) OR IN
THE OUTER MEMBRANE.
SIMILARITY: TO OTHER SPECIES OMPH OUTER MEMBRANE PROTEIN.
|
| | lpxD | b0179 | UDP-3-O-(3-hydroxymyristoyl)-glucosamine N-acyltransferase; third step of endotoxin (lipidA) synthesis |
EG10316 |
CATALYTIC ACTIVITY: UDP-3-O-(3-HYDROXYTETRADECANOYL)GLUCOSAMINE
+ (R)-3-HYDROXYTETRADECANOYL-[ACYL-CARRIER PROTEIN] =
UDP-2,3-BIS(3-HYDROXYTETRADECANOYL)GLUCOSAMINE + [ACYL-CARRIER
PROTEIN].
PATHWAY: THIRD STEP IN LIPID A BIOSYNTHESIS.
MISCELLANEOUS: THE MUTANTS FIRA200, FIRA201 AND OMSA CONFER
TEMPERATURE SENSITIVITY. FIRA200 REVERSES THE RIFAMPIN RESISTANCE
OF RPOB MUTANTS.
SIMILARITY: BELONGS TO THE CYSE/LACA/LPXA/NODL FAMILY OF
ACETYLTRANSFERASES. COMPOSED OF MULTIPLE REPEATS OF [LIV]-G-X(4).
CAUTION: WAS ORIGINALLY THOUGHT TO BE INVOLVED IN TRANSCRIPTION.
|
| | fabZ | b0180 | (3R)-hydroxymyristol acyl carrier protein dehydratase |
EG11284 |
FUNCTION: INVOLVED IN SATURATED FATTY ACIDS BIOSYNTHESIS.
SUBUNIT: OLIGOMER.
SUBCELLULAR LOCATION: CYTOPLASMIC.
PTM: THE N-TERMINUS IS BLOCKED.
SIMILARITY: BELONGS TO THE THIOESTER DEHYDRATASE FAMILY.
|
| | lpxA | b0181 | UDP-N-acetylglucosamine acetyltransferase; lipid A biosynthesis |
EG10545 |
FUNCTION: INVOLVED IN THE BIOSYNTHESIS OF LIPID A, A
PHOSPHORYLATED GLYCOLIPID THAT ANCHORS THE LIPOPOLYSACCHARIDE TO
THE OUTER MEMBRANE OF THE CELL.
CATALYTIC ACTIVITY: (R)-3-HYDROXYTETRADECANOYL-[ACYL-CARRIER
PROTEIN] + UDP-N-ACETYLGLUCOSAMINE = [ACYL-CARRIER PROTEIN] +
UDP-3-O-(3-HYDROXYTETRADECANOYL)-N-ACETYLGLUCOSAMINE.
PATHWAY: LIPID A BIOSYNTHESIS; FIRST STEP.
SUBUNIT: HOMOTRIMER.
SUBCELLULAR LOCATION: CYTOPLASMIC.
SIMILARITY: BELONGS TO THE TRANSFERASE HEXAPEPTIDE REPEAT FAMILY.
LPXA SUBFAMILY.
|
| | lpxB | b0182 | tetraacyldisaccharide-1-P; lipid A biosynthesis, penultimate step |
EG10546 |
FUNCTION: CONDENSATION OF UDP-2,3-DIACYLGLUCOSAMINE AND
2,3-DIACYLGLUCOSAMINE-1-PHOSPHATE TO FORM LIPID A DISACCHARIDE,
A PRECURSOR OF LIPID A, A PHOSPHORYLATED GLYCOLIPID THAT ANCHORS
THE LIPOPOLYSACCHARIDE TO THE OUTER MEMBRANE OF THE CELL.
CATALYTIC ACTIVITY: UDP-2,3-BIS(3-HYDROXYTETRADECANOYL)GLUCOSAMINE
+ 2,3-BIS(3-HYDROXYTETRADECANOYL)-BETA-D-GLUCOSAMINYL 1-PHOSPHATE
= UDP + 2,3-BIS(3-HYDROXYTETRADECANOYL)-D-GLUCOSAMINYL-1,6-BETA-
D-2,3-BIS(3-HYDROXYTETRADECANOYL)-BETA-D-GLUCOSAMINYL 1-PHOSPHATE.
PATHWAY: LIPID A BIOSYNTHESIS.
SIMILARITY: BELONGS TO THE LPXB FAMILY.
|
| | rnhB | b0183 | RNAse HII, degrades RNA of DNA-RNA hybrids |
EG10861 |
FUNCTION: DEGRADES THE RIBONUCLEOTIDE MOIETY ON RNA-DNA HYBRID
MOLECULES.
CATALYTIC ACTIVITY: ENDONUCLEOLYTIC CLEAVAGE TO 5'-PHOSPHO-
MONOESTER.
COFACTOR: REQUIRES MANGANESE FOR ACTIVITY.
SUBCELLULAR LOCATION: CYTOPLASMIC (POTENTIAL).
SIMILARITY: BELONGS TO THE RNASE HII FAMILY.
|
| | dnaE | b0184 | DNA polymerase III, alpha subunit |
EG10238 |
FUNCTION: DNA POLYMERASE III IS A COMPLEX, MULTICHAIN ENZYME
RESPONSIBLE FOR MOST OF THE REPLICATIVE SYNTHESIS IN BACTERIA.
THIS DNA POLYMERASE ALSO EXHIBITS 3' TO 5' EXONUCLEASE ACTIVITY.
THE ALPHA CHAIN IS THE DNA POLYMERASE.
CATALYTIC ACTIVITY: N DEOXYNUCLEOSIDE TRIPHOSPHATE =
N PYROPHOSPHATE + DNA(N).
SUBUNIT: CONTAINS A CORE (COMPOSED OF ALPHA, EPSILON, AND THETA
CHAINS) THAT ASSOCIATES WITH A TAU SUBUNIT WHICH ALLOW THE CORE
DIMERIZATION TO FORM THE POLIII' COMPLEX. POLIII' ASSOCIATES WITH
THE GAMMA COMPLEX (COMPOSED OF CHAINS GAMMA, DELTA, DELTA', PSI,
AND CHI) AND WITH THE BETA CHAIN. THE FINAL COMPOSITION OF THE
COMPLEX IS: (ALPHA,EPSILON,THETA)[2]-TAU[2]-(GAMMA,DELTA,DELTA',
PSI,CHI)[2]-BETA[4].
SUBCELLULAR LOCATION: CYTOPLASMIC.
SIMILARITY: BELONGS TO DNA POLYMERASE TYPE-C FAMILY. DNAE
SUBFAMILY.
|
| | accA | b0185 | acetylCoA carboxylase, carboxytransferase component, alpha subunit |
EG11647 |
FUNCTION: THIS PROTEIN IS A COMPONENT OF THE ACETYL COENZYME A
CARBOXYLASE COMPLEX; FIRST, BIOTIN CARBOXYLASE CATALYZES THE
CARBOXYLATION OF THE CARRIER PROTEIN AND THEN THE TRANSCARBOXYLASE
TRANSFERS THE CARBOXYL GROUP TO FORM MALONYL-COA.
CATALYTIC ACTIVITY: CARBOXYBIOTIN CARBOXYL CARRIER PROTEIN +
ACETYL-COA = BIOTIN CARBOXYL CARRIER PROTEIN + MALONYL-COA.
PATHWAY: FIRST STEP IN LONG-CHAIN FATTY ACID SYNTHESIS.
SUBUNIT: ACETYL-COA CARBOXYLASE IS AN HETEROHEXAMER OF BIOTIN
CARBOXYL CARRIER PROTEIN, BIOTIN CARBOXYLASE AND THE TWO SUBUNITS
OF CARBOXYL TRANSFERASE IN A 2:2 COMPLEX.
SIMILARITY: TO THE C-TERMINUS OF MAMMALIAN PROPIONYL-COA
CARBOXYLASE BETA CHAIN.
|
| | ldcC | b0186 | lysine decarboxylase 2, constitutive |
EG13219 |
FUNCTION: LDC IS CONSTITUTIVELY BUT WEAKLY EXPRESSED UNDER VARIOUS
CONDITIONS. OPTIMUM ACTIVITY IS ACHIEVED BETWEEN PH 6.2 TO 8.0.
CATALYTIC ACTIVITY: L-LYSINE = CADAVERINE + CO(2).
COFACTOR: PYRIDOXAL PHOSPHATE.
SUBUNIT: HOMODECAMER.
SIMILARITY: BELONGS TO FAMILY 1 OF ORNITHINE, LYSINE, AND ARGININE
DECARBOXYLASES.
|
| | yaeR | b0187 | orf, hypothetical protein |
EG13224 |
SIMILARITY: STRONG, TO B.SUBTILIS YWKD.
|
| | mesJ | b0188 | cell cycle protein |
EG13220 |
SIMILARITY: BELONGS TO THE UPF0072 (MESJ/YCF62) FAMILY.
|
| 0.128941 | + | b1170 | b1170 | putative part of putative ATP-binding component of a transport system |
|
|
| 0.124770 | + | yidY | b3710 | putative transport protein |
EG11720 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE
(PROBABLE).
SIMILARITY: BELONGS TO THE MAJOR FACILITATOR FAMILY (ALSO KNOWN
AS THE DRUG RESISTANCE TRANSLOCASE FAMILY).
|
| | yidZ | b3711 | putative transcriptional regulator LYSR-type |
EG11721 |
SIMILARITY: BELONGS TO THE LYSR FAMILY OF TRANSCRIPTIONAL
REGULATORS.
|
| | yieE | b3712 | orf, hypothetical protein |
EG11722 |
|
| | yieF | b3713 | orf, hypothetical protein |
EG11723 |
SIMILARITY: BELONGS TO THE SSUE FAMILY.
|
| 0.122982 | + | yhdJ | b3262 | putative methyltransferase |
EG11498 |
CATALYTIC ACTIVITY: S-ADENOSYL-L-METHIONINE + DNA ADENINE =
S-ADENOSYL-L-HOMOCYSTEINE + DNA 6-METHYLAMINOPURINE.
SIMILARITY: BELONGS TO THE N-6 ADENINE-SPECIFIC DNA METHYLASE
FAMILY.
|
| | yhdU | b3263 | orf, hypothetical protein |
EG12832 |
|
| 0.110620 | - | glnH | b0811 | periplasmic glutamine-binding protein; permease |
EG10386 |
FUNCTION: INVOLVED IN A GLUTAMINE-TRANSPORT SYSTEM GLNHPQ.
SUBCELLULAR LOCATION: PERIPLASMIC.
INDUCTION: LACK OF GLUTAMINE.
SIMILARITY: BELONGS TO THE BACTERIAL EXTRACELLULAR SOLUTE-BINDING
PROTEIN FAMILY 3.
|
| | glnP | b0810 | glutamine high-affinity transport system; membrane component |
EG10388 |
FUNCTION: PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM
FOR GLUTAMINE; PROBABLY RESPONSIBLE FOR THE TRANSLOCATION OF THE
SUBSTRATE ACROSS THE MEMBRANE.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE.
INDUCTION: LACK OF GLUTAMINE.
SIMILARITY: WITH INTEGRAL MEMBRANE COMPONENTS OF OTHER BINDING-
PROTEIN-DEPENDENT TRANSPORT SYSTEMS. BELONGS TO THE HISMQ
SUBFAMILY.
|
| | glnQ | b0809 | ATP-binding component of glutamine high-affinity transport system |
EG10389 |
FUNCTION: PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM
FOR GLUTAMINE. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE
TRANSPORT SYSTEM.
SUBCELLULAR LOCATION: INNER MEMBRANE-ASSOCIATED.
INDUCTION: LACK OF GLUTAMINE.
SIMILARITY: BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY
(ABC TRANSPORTERS).
|
| | ybiO | b0808 | putative transport protein |
EG13320 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN (POTENTIAL).
SIMILARITY: BELONGS TO THE UPF0003 FAMILY.
|
| 0.095835 | - | yagB | b0266 | orf, hypothetical protein |
EG12339 |
SIMILARITY: TO E.COLI YAFW, YEEU AND YFJZ.
CAUTION: REF.1 SEQUENCE DIFFERS FROM THAT SHOWN DUE TO A
FRAMESHIFT.
|
| 0.093324 | + | recQ | b3822 | ATP-dependent DNA helicase |
EG10833 |
FUNCTION: INVOLVED IN THE RECF RECOMBINATION PATHWAY; ITS GENE
EXPRESSION IS UNDER THE REGULATION OF THE SOS SYSTEM. IT IS A DNA
HELICASE.
SIMILARITY: BELONGS TO THE RECQ SUBFAMILY OF HELICASES.
|
| 0.087588 | + | mutS | b2733 | methyl-directed mismatch repair |
EG10625 |
FUNCTION: THIS PROTEIN IS INVOLVED IN THE REPAIR OF MISMATCHES
IN DNA. IT IS POSSIBLE THAT IT CARRY OUT THE MISMATCH RECOGNITION
STEP. THIS PROTEIN HAS A WEAK ATPASE ACTIVITY.
SIMILARITY: BELONGS TO THE DNA MISMATCH REPAIR MUTS FAMILY.
|
| | pphB | b2734 | protein phosphatase 2 |
EG13102 |
FUNCTION: HAS BEEN SHOWN, IN VITRO, TO ACT ON SER, THR AND
TYR-PHOSPHORYLATED SUBSTRATES.
CATALYTIC ACTIVITY: A PHOSPHOPROTEIN + H(2)O = A PROTEIN +
ORTHOPHOSPHATE.
SIMILARITY: BELONGS TO THE PPP FAMILY OF PHOSPHATASES.
|
| 0.085413 | + | cof | b0446 | orf, hypothetical protein |
EG13216 |
SIMILARITY: BELONGS TO THE COF/YBHA/YIDA/YIGL (E.COLI) / YCSE/YXEH
(B.SUBTILIS) FAMILY.
|
| | ybaO | b0447 | putative LRP-like transcriptional regulator |
EG13218 |
SIMILARITY: BELONGS TO THE ASNC FAMILY OF TRANSCRIPTIONAL
REGULATORS.
|
| | mdlA | b0448 | ATP-binding component of a transport system |
EG11622 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE
(POTENTIAL).
SIMILARITY: BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY
(ABC TRANSPORTERS). MDR SUBFAMILY.
CAUTION: REF.1 SEQUENCE DIFFERS FROM THAT SHOWN DUE TO A
FRAMESHIFT THAT FUSES MDLA AND MDLB.
|
| | mdlB | b0449 | putative ATP-binding component of a transport system |
EG14374 |
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE
(POTENTIAL).
SIMILARITY: BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY
(ABC TRANSPORTERS). MDR SUBFAMILY.
CAUTION: REF.1 SEQUENCE DIFFERS FROM THAT SHOWN DUE TO A
FRAMESHIFT THAT FUSES MDLA AND MDLB.
|
| 0.082328 | + | yggJ | b2946 | orf, hypothetical protein |
EG12366 |
SIMILARITY: BELONGS TO THE UPF0088 FAMILY. STRONG, TO H.INFLUENZAE
HI0303.
|
| | gshB | b2947 | glutathione synthetase |
EG10419 |
CATALYTIC ACTIVITY: ATP + GAMMA-L-GLUTAMYL-L-CYSTEINE + GLYCINE =
ADP + ORTHOPHOSPHATE + GLUTATHIONE.
ENZYME REGULATION: INHIBITED BY 7,8-DIHYDROFOLATE, METHOTREXATE,
AND TRIMETHOPRIM.
PATHWAY: SECOND STEP IN GLUTATHIONE BIOSYNTHESIS.
SUBUNIT: HOMOTETRAMER.
SIMILARITY: BELONGS TO THE PROKARYOTIC GSH SYNTHASE FAMILY.
|
| | yqgE | b2948 | orf, hypothetical protein |
EG13289 |
SIMILARITY: STRONG, TO H.INFLUENZAE HI0304.
|
| | yqgF | b2949 | orf, hypothetical protein |
EG13290 |
SIMILARITY: BELONGS TO THE UPF0081 FAMILY. STRONG, TO H.INFLUENZAE
HI0305 AND B. APHIDICOLA (SUBSP. ACYRTHOSIPHON PISUM) BU548.
|
| 0.081177 | - | yfeA | b2395 | orf, hypothetical protein |
EG11145 |
SIMILARITY: CONTAINS 1 DUF2 DOMAIN.
CAUTION: REF.3 SEQUENCE DIFFERS FROM THAT SHOWN DUE TO A
FRAMESHIFT IN POSITION 112.
|
| 0.080096 | - | phnQ | b4091 | orf, hypothetical protein |
|
MISCELLANEOUS: THE SEQUENCE SHOWN IS THAT OF STRAIN K12.
CAUTION: THIS SEQUENCE, ACCORDING TO THE ECOSEQ DATABASE (K. RUDD)
AS WELL AS WANNER B.L. IS MOST PROBABLY NOT A REAL PROTEIN;
THEREFORE THIS ENTRY WILL PROBABLY BE DELETED IN FUTURE RELEASES.
|
| 0.079414 | + | rbsD | b3748 | D-ribose high-affinity transport system; membrane-associated protein |
EG10817 |
FUNCTION: INVOLVED IN THE HIGH-AFFINITY RIBOSE MEMBRANE TRANSPORT
SYSTEM.
SUBCELLULAR LOCATION: INNER MEMBRANE-ASSOCIATED (POTENTIAL).
|
| | rbsA | b3749 | ATP-binding component of D-ribose high-affinity transport system |
EG10814 |
FUNCTION: PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM
FOR RIBOSE. PROBABLY RESPONSIBLE FOR ENERGY COUPLING TO THE
TRANSPORT SYSTEM.
SUBCELLULAR LOCATION: INNER MEMBRANE-ASSOCIATED.
DOMAIN: COMPOSED OF TWO HOMOLOGOUS DOMAINS.
SIMILARITY: BELONGS TO THE ATP-BINDING TRANSPORT PROTEIN FAMILY
(ABC TRANSPORTERS). MGLA/RBSA SUBFAMILY.
|
| | rbsC | b3750 | D-ribose high-affinity transport system |
EG10816 |
FUNCTION: PART OF THE BINDING-PROTEIN-DEPENDENT TRANSPORT SYSTEM
FOR RIBOSE. PROBABLY RESPONSIBLE FOR THE TRANSLOCATION OF THE
SUBSTRATE ACROSS THE MEMBRANE.
SUBCELLULAR LOCATION: INTEGRAL MEMBRANE PROTEIN. INNER MEMBRANE.
SIMILARITY: WITH INTEGRAL MEMBRANE COMPONENTS OF OTHER BINDING-
PROTEIN-DEPENDENT TRANSPORT SYSTEMS. BELONGS TO THE ARAH/RBSC
SUBFAMILY.
|
| | rbsB | b3751 | D-ribose periplasmic binding protein |
EG10815 |
FUNCTION: INVOLVED IN THE HIGH-AFFINITY D-RIBOSE MEMBRANE
TRANSPORT SYSTEM AND ALSO SERVES AS THE PRIMARY CHEMORECEPTOR FOR
CHEMOTAXIS.
SUBCELLULAR LOCATION: PERIPLASMIC.
SIMILARITY: BELONGS TO THE BACTERIAL EXTRACELLULAR SOLUTE-BINDING
RECEPTOR FAMILY 2.
|
| | rbsK | b3752 | ribokinase |
EG10818 |
CATALYTIC ACTIVITY: ATP + D-RIBOSE = ADP + D-RIBOSE 5-PHOSPHATE.
PATHWAY: FIRST STEP IN RIBOSE METABOLISM.
SUBUNIT: HOMODIMER.
SUBCELLULAR LOCATION: CYTOPLASMIC.
SIMILARITY: BELONGS TO THE PFKB FAMILY OF CARBOHYDRATE KINASES.
|
| | rbsR | b3753 | regulator for rbs operon |
EG10819 |
FUNCTION: TRANSCRIPTIONAL REPRESSOR FOR THE RIBOSE RBSDACBK
OPERON. RBSR BINDS TO A REGION OF PERFECT DYAD SYMMETRY SPANNING
THE RBS OPERON TRANSCRIPTIONAL START SITE. THE AFFINITY FOR THE
RBS OPERATOR IS REDUCED BY ADDITION OF RIBOSE, CONSISTENT WITH
RIBOSE BEING THE INDUCER OF THE OPERON.
SIMILARITY: BELONGS TO THE LACI FAMILY OF TRANSCRIPTIONAL
REGULATORS.
|
| 0.076254 | + | yfeC | b2398 | orf, hypothetical protein |
EG11431 |
SIMILARITY: TO E.COLI YFII AND TO P.AERUGINOSA ORFW (AC P33640).
|
| | yfeD | b2399 | orf, hypothetical protein |
EG11432 |
|
| 0.075338 | - | ygfF | b2902 | putative oxidoreductase |
EG12971 |
SIMILARITY: BELONGS TO THE SHORT-CHAIN DEHYDROGENASES/REDUCTASES
(SDR) FAMILY.
|
| 0.073262 | + | apt | b0469 | adenine phosphoribosyltransferase |
EG10051 |
FUNCTION: CATALYSES A SALVAGE REACTION RESULTING IN THE FORMATION
OF AMP, THAT IS ENERGICALLY LESS COSTLY THAN DE NOVO SYNTHESIS.
CATALYTIC ACTIVITY: AMP + PYROPHOSPHATE = ADENINE + 5-PHOSPHO-
ALPHA-D-RIBOSE 1-DIPHOSPHATE.
PATHWAY: PURINE SALVAGE.
SUBUNIT: HOMODIMER.
SUBCELLULAR LOCATION: CYTOPLASMIC.
SIMILARITY: BELONGS TO THE PURINE/PYRIMIDINE
PHOSPHORIBOSYLTRANSFERASE FAMILY.
|
| | dnaX | b0470 | DNA polymerase III, tau and gamma subunits; DNA elongation factor III |
EG10245 |
FUNCTION: DNA POLYMERASE III IS A COMPLEX, MULTICHAIN ENZYME
RESPONSIBLE FOR MOST OF THE REPLICATIVE SYNTHESIS IN BACTERIA.
THIS DNA POLYMERASE ALSO EXHIBITS 3' TO 5' EXONUCLEASE ACTIVITY.
FUNCTION: THE TAU CHAIN SERVES AS A SCAFFOLD TO HELP IN THE
DIMERIZATON OF THE CORE COMPLEX.
FUNCTION: THE GAMMA CHAIN SEEMS TO INTERACT WITH THE DELTA
SUBUNIT TO TRANSFER THE BETA SUBUNIT ON THE DNA.
CATALYTIC ACTIVITY: N DEOXYNUCLEOSIDE TRIPHOSPHATE =
N PYROPHOSPHATE + DNA(N).
SUBUNIT: CONTAINS A CORE (COMPOSED OF ALPHA, EPSILON, AND THETA
CHAINS) THAT ASSOCIATES WITH A TAU SUBUNIT WHICH ALLOW THE CORE
DIMERIZATION TO FORM THE POLIII' COMPLEX. POLIII' ASSOCIATES WITH
THE GAMMA COMPLEX (COMPOSED OF CHAINS GAMMA, DELTA, DELTA', PSI,
AND CHI) AND WITH THE BETA CHAIN. THE FINAL COMPOSITION OF THE
COMPLEX IS: (ALPHA,EPSILON,THETA)[2]-TAU[2]-(GAMMA,DELTA,DELTA',
PSI,CHI)[2]-BETA[4].
ALTERNATIVE PRODUCTS: THE PRODUCTION OF THE TWO PROTEIN PRODUCTS
FROM THIS REGION IS DUE TO PROGRAMMED RIBOSOMAL FRAMESHIFTING.
SIMILARITY: PARTIAL TO PHAGE T4 DNA POLYMERASE ACCESSORY PROTEIN
44 AND TO HUMAN ACTIVATOR 1, 37 AND 40 KDA SUBUNITS.
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| | ybaB | b0471 | orf, hypothetical protein |
EG11100 |
SIMILARITY: BELONGS TO THE UPF0133 FAMILY.
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| | recR | b0472 | recombination and repair |
EG10834 |
FUNCTION: MAY PLAY A ROLE IN DNA REPAIR. IT SEEMS TO BE INVOLVED
IN AN RECBC-INDEPENDENT RECOMBINATIONAL PROCESS OF DNA REPAIR. IT
MAY ACT WITH RECF AND RECO.
SIMILARITY: BELONGS TO THE RECR FAMILY.
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| | htpG | b0473 | chaperone Hsp90, heat shock protein C 62.5 |
EG10461 |
FUNCTION: MOLECULAR CHAPERONE. HAS ATPASE ACTIVITY.
SIMILARITY: BELONGS TO THE HEAT SHOCK PROTEIN 90 FAMILY.
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| 0.072727 | + | yajQ | b0426 | orf, hypothetical protein |
EG13613 |
SIMILARITY: STRONG, TO H.INFLUENZAE HI1034.
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| 0.072340 | + | b3122 | b3122 | orf, hypothetical protein |
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| 0.071395 | + | yjeR | b4162 | orf, hypothetical protein |
EG12480 |
FUNCTION: 3'-TO-5' EXORIBONUCLEASE SPECIFIC FOR SMALL
OLIGORIBONUCLEOTIDES.
SUBUNIT: HOMODIMER.
SUBCELLULAR LOCATION: CYTOPLASMIC (POTENTIAL).
SIMILARITY: BELONGS TO THE OLIGORIBONUCLEASE FAMILY.
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| 0.070226 | + | yaeG | b0162 | orf, hypothetical protein |
EG12335 |
FUNCTION: SEEMS TO REGULATE THE EXPRESSION OF THE OPERONS FOR THE
ENZYMES INVOLVED IN D-GALACTARATE, D-GLUCARATE AND D-GLYCERATE
UTILIZATION.
SIMILARITY: BELONGS TO THE CDAR FAMILY.
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| 0.067799 | - | malI | b1620 | repressor of malX and Y genes |
EG10557 |
FUNCTION: MALI IS A REPRESSOR FOR THE MALX AND MALY GENES.
ALSO REGULATES ITS OWN EXPRESSION. BINDS MALTOSE AS AN INDUCER.
SIMILARITY: BELONGS TO THE LACI FAMILY OF TRANSCRIPTIONAL
REGULATORS.
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| | hdhA | b1619 | NAD-dependent 7alpha-hydroxysteroid dehydrogenase, dehydroxylation of bile acids |
EG10425 |
FUNCTION: 7-ALPHA-DEHYDROXYLATION OF CHOLIC ACID, YIELDING
DEOXYCHOLIC ACID AND LITHOCHOLIC ACID, RESPECTIVELY. HIGHEST
AFFINITY WITH TAUROCHENODEOXYCHOLIC ACID.
CATALYTIC ACTIVITY: 3-ALPHA,7-ALPHA,12-ALPHA-TRIHYDROXY-5-BETA-
CHOLANATE + NAD(+) = 3-ALPHA,12-ALPHA-DIHYDROXY-7-OXO-5-BETA-
CHOLANATE + NADH.
SUBUNIT: HOMOTETRAMER.
SIMILARITY: BELONGS TO THE SHORT-CHAIN DEHYDROGENASES/REDUCTASES
(SDR) FAMILY.
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| 0.067628 | + | yibK | b3606 | orf, hypothetical protein |
EG11888 |
SIMILARITY: BELONGS TO THE RNA METHYLTRANSFERASE TRMH FAMILY.
STRONG, TO H.INFLUENZAE HI0766.
CAUTION: POSSIBLY IDENTICAL TO GLTE.
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| 0.065698 | + | talA | b2464 | transaldolase A |
EG11797 |
FUNCTION: TRANSALDOLASE IS IMPORTANT FOR THE BALANCE OF
METABOLITES IN THE PENTOSE-PHOSPHATE PATHWAY.
CATALYTIC ACTIVITY: SEDOHEPTULOSE 7-PHOSPHATE + D-GLYCERALDEHYDE
3-PHOSPHATE = D-ERYTHROSE 4-PHOSPHATE + D-FRUCTOSE 6-PHOSPHATE.
PATHWAY: NONOXYDATIVE PART OF THE PENTOSE-PHOSPHATE PATHWAY.
SUBCELLULAR LOCATION: CYTOPLASMIC (PROBABLE).
SIMILARITY: BELONGS TO THE TRANSALDOLASE FAMILY.
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| | tktB | b2465 | transketolase 2 isozyme |
EG12100 |
CATALYTIC ACTIVITY: SEDOHEPTULOSE 7-PHOSPHATE + D-GLYCERALDEHYDE
3-PHOSPHATE = D-RIBOSE 5-PHOSPHATE + D-XYLULOSE 5-PHOSPHATE.
COFACTOR: THIAMINE PYROPHOSPHATE.
SIMILARITY: BELONGS TO THE TRANSKETOLASE FAMILY.
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